Publications

Grahammer F, Dumoulin B, Gulieva RE, Wu H, Xu Y, Sulaimanov N, Arnold F, Sandner L, Cordts T, Todkar A, Moulin P, Reichardt W, Puelles VG, Kramann R, Freedman BS, Busch H, Boerries M, Walz G, Huber TB (2024) Cyclin-dependent kinase 4 drives cystic kidney disease in the absence of mTORC1 signaling activity Kidney Int, doi: 10.1016/j.kint.2024.08.021. Epub ahead of print.
Leroy C, Lang K, Spitz D, Milosavljevic J, Heinkele H, Kayser S, Helmstädter M, Walz G, Ulbrich MH, Hermle T (2024) Linking Basement Membrane and Slit Diaphragm in Drosophila Nephrocytes J Am Soc Nephrol, doi: 10.1681/ASN.0000000000000400. Epub ahead of print.
Matuschik L, Seifert G, Lammich K, Holzner P, Tanriver Y, Fichtner-Feigl S, Walz G, Schneider J, Jänigen B (2024) Non-antigen-specific Immunoadsorption Is a Risk Factor for Severe Postoperative Infections in ABO-Incompatible Kidney Transplant Recipients Transpl Int, doi: 10.3389/ti.2024.12263.
Yasunaga T, Wiegel J, Bergen MD, Helmstädter M, Epting D, Paolini A, Çiçek Ö, Radziwill G, Engel C, Brox T, Ronneberger O, Walentek P, Ulbrich MH, Walz G (2024) Author Correction: Microridge-like structures anchor motile cilia Nat Commun, doi: 10.1038/s41467-024-52323-4. Erratum for: Nat Commun. 2022 Apr 19;13(1):2056. doi: 10.1038/s41467-022-29741-3.
Ganner A, Philipp A, Lagies S, Wingendorf L, Wang L, Pilz F, Welte T, Grand K, Lienkamp SS, Klein M, Kammerer B, Frew IJ, Walz G, Neumann-Haefelin E (2023) SCD5 Regulation by VHL Affects Cell Proliferation and Lipid Homeostasis in ccRCC. Cells, doi: 10.3390/cells12060835.
Wang H, Zaiser F, Eckert P, Ruf J, Kayser N, Veenstra AC, Müller M, Haas R, Walz G, Yakulov TA. (2023) Inversin (NPHP2) and Vangl2 are required for normal zebrafish cloaca formation. Biochem Biophys Res Commun, doi: 10.1016/j.bbrc.2023.06.058.
Wäsch R, Strüssmann T, Wehr C, Marks R, Meyer PT, Walz G, Engelhardt M. (2023) Safe and successful CAR T-cell therapy targeting BCMA in a multiple myeloma patient requiring hemodialysis. Ann Hematol, doi: 10.1007/s00277-023-05163-z.
Tsang TH, Wiese M, Helmstädter M, Stehle T, Seyfferth J, Shvedunova M, Holz H, Walz G, Akhtar A. (2023) Transcriptional regulation by the NSL complex enables diversification of IFT functions in ciliated versus nonciliated cells. Sci Adv, doi: 10.1126/sciadv.adh5598.
Schneider J, Wobser R, Kühn W, Wagner D, Tanriver Y, Walz G. (2023) Nirmatrelvir/ritonavir treatment in SARS-CoV-2 positive kidney transplant recipients - a case series with four patients. BMC Nephrol, doi: 10.1186/s12882-023-03154-w.
Yasunaga T, Wiegel J, Bergen MD, Helmstädter M, Epting D, Paolini A, Çiçek Ö, Radziwill G, Engel C, Brox T, Ronneberger O, Walentek P, Ulbrich MH, Walz G. (2022) Microridge-like structures anchor motile cilia. Nat Commun, doi: 10.1038/s41467-022-29741-3.
Klingbeil K, Nguyen TQ, Fahrner A, Guthmann C, Wang H, Schoels M, Lilienkamp M, Franz H, Eckert P, Walz G, Yakulov TA. (2022) Corpuscles of Stannius development requires FGF signaling. Dev Biol, doi: 10.1016/j.ydbio.2021.10.005.
Rogg M, Maier JI, Van Wymersch C, Helmstädter M, Sammarco A, Lindenmeyer M, Zareba P, Montanez E, Walz G, Werner M, Endlich N, Benzing T, Huber TB, Schell C. (2022) alpha-Parvin Defines a Specific Integrin Adhesome to Maintain the Glomerular Filtration Barrier. J Am Soc Nephrol, doi: 10.1681/ASN.2021101319.
Gerstner L, Chen M, Kampf LL, Milosavljevic J, Lang K, Schneider R, Hildebrandt F, Helmstädter M, Walz G, Hermle T. (2022) Inhibition of endoplasmic reticulum stress signaling rescues cytotoxicity of human apolipoprotein-L1 risk variants in Drosophila. Kidney Int, doi: 10.1016/j.kint.2021.12.031.
Zhang Z, Zhang F, Davis AK, Xin M, Walz G, Tian W, Zheng Y. (2022) CDC42 controlled apical-basal polarity regulates intestinal stem cell to transit amplifying cell fate transition via YAP-EGF-mTOR signaling. Cell Rep, doi: 10.1016/j.celrep.2021.110009.
Koehler S, Odenthal J, Ludwig V, Unnersjö Jess D, Höhne M, Jüngst C, Grawe F, Helmstädter M, Janku JL, Bergmann C, Hoyer PF, Hagmann HH, Walz G, Bloch W, Niessen C, Schermer B, Wodarz A, Denholm B, Benzing T, Iden S, Brinkkoetter PT. (2022) Scaffold polarity proteins Par3A and Par3B share redundant functions while Par3B acts independent of atypical protein kinase C/Par6 in podocytes to maintain the kidney filtration barrier. Kidney Int, doi: 10.1016/j.kint.2021.11.030.
Bona A, Seifert M, Thünauer R, Zodel K, Frew IJ, Römer W, Walz G, Yakulov TA. (2022) MARVEL domain containing CMTM4 affects CXCR4 trafficking. Mol Biol Cell, doi: 10.1091/mbc.E22-05-0152.
Kayser N, Zaiser F, Veenstra AC, Wang H, Göcmen B, Eckert P, Franz H, Köttgen A, Walz G, Yakulov TA. (2022) Clock genes rescue nphp mutations in zebrafish. Hum Mol Genet, doi: 10.1093/hmg/ddac160.
Spitz D, Comas M, Gerstner L, Kayser S, Helmstädter M, Walz G, Hermle T. (2022) mTOR-Dependent Autophagy Regulates Slit Diaphragm Density in Podocyte-like Drosophila Nephrocytes. Cells, doi: 10.3390/cells11132103.
Lang K, Milosavljevic J, Heinkele H, Chen M, Gerstner L, Spitz D, Kayser S, Helmstädter M, Walz G, Köttgen M, Spracklen A, Poulton J, Hermle T. (2022) Selective endocytosis controls slit diaphragm maintenance and dynamics in Drosophila nephrocytes. Elife, doi: 10.7554/eLife.79037.
Gessler S, Guthmann C, Schuler V, Lilienkamp M, Walz G, Yakulov TA. (2022) Control of Directed Cell Migration after Tubular Cell Injury by Nucleotide Signaling. Int J Mol Sci, doi: 10.3390/ijms23147870.
Milosavljevic J, Lempicki C, Lang K, Heinkele H, Kampf LL, Leroy C, Chen M, Gerstner L, Spitz D, Wang M, Knob AU, Kayser S, Helmstädter M, Walz G, Pollak MR, Hermle T. (2022) Nephrotic Syndrome Gene TBC1D8B Is Required for Endosomal Maturation and Nephrin Endocytosis in Drosophila. J Am Soc Nephrol, doi: 10.1681/ASN.2022030275.
Zhuang M, Scholz A, Walz G, Yakulov TA. (2022) Histone Deacetylases Cooperate with NF-KappaB to Support the Immediate Migratory Response after Zebrafish Pronephros Injury. Int J Mol Sci, doi: 10.3390/ijms23179582.
Eklou ND, Jänigen BM, Pisarski P, Walz G, Schneider J. (2022) Evaluation of Deceased Donor Kidney Transplantation in the Eurotransplant Senior Program in Comparison to Standard Allocation. Ann Transplant, doi: 10.12659/AOT.936514.
Rogg M, Maier JI, Dotzauer R, Artelt N, Kretz O, Helmstädter M, Abed A, Sammarco A, Sigle A, Sellung D, Dinse P, Reiche K, Yasuda-Yamahara M, Biniossek ML, Walz G, Werner M, Endlich N, Schilling O, Huber TB, Schell C. (2021) SRGAP1 Controls Small Rho GTPases To Regulate Podocyte Foot Process Maintenance. J Am Soc Nephrol, doi: 10.1681/ASN.2020081126.
Schneider J, Walz G, Neumann-Haefelin E. (2021) Hypertensive Erkrankungen in der Schwangerschaft [Hypertensive Disorders in Pregnancy] Dtsch Med Wochenschr, doi: 10.1055/a-1233-7685. [Article in German]
Schoels M, Zhuang M, Fahrner A, Küchlin S, Sagar, Franz H, Schmitt A, Walz G, Yakulov TA. (2021) Single-cell mRNA profiling reveals changes in solute carrier expression and suggests a metabolic switch during zebrafish pronephros development Am J Physiol Renal Physiol, doi: 10.1152/ajprenal.00610.2020.
Schneider J, Jaenigen B, Wagner D, Rieg S, Hornuss D, Biever PM, Kern WV, Walz G. (2021) Therapy with lopinavir/ritonavir and hydroxychloroquine is associated with acute kidney injury in COVID-19 patients PLoS One, doi: 10.1371/journal.pone.0249760.
Maier JI, Rogg M, Helmstädter M, Sammarco A, Walz G, Werner M, Schell C. (2021) A Novel Model for Nephrotic Syndrome Reveals Associated Dysbiosis of the Gut Microbiome and Extramedullary Hematopoiesis. Cells, doi: 10.3390/cells10061509.
Schneider J, Venhoff N, Walz G. (2021) Ruptured Intrarenal Arterial Aneurysm in a Patient With Granulomatosis With Polyangiitis J Rheumatol, doi: 10.3899/jrheum.190986.
Henningsen M, Jaenigen B, Zschiedrich S, Pisarski P, Walz G, Schneider J. (2021) Risk Factors and Management of Leukopenia After Kidney Transplantation: A Single-Center Experience Transplant Proc, doi: 10.1016/j.transproceed.2021.04.011.
Kotsis F, Janusch H, Li Y, Viau A, Epting D, Kramer-Zucker A, Walz G, Nitschke R, Lorentzen E, Ganner A, Neumann-Haefelin E, Kuehn EW, Boehlke C. (2021) Ift88, but not Kif3a, is required for establishment of the periciliary membrane compartment. Biochem Biophys Res Commun, doi: 10.1016/j.bbrc.2021.10.075.
Gebauer E, Bechtel-Walz W, Schell C, Erbel M, Walz G, Hermle T. (2021) Development of Nivolumab/Ipilimumab-Associated Autoimmune Nephritis during Steroid Therapy. Case Rep Nephrol Dial, doi: 10.1159/000517502.
Estrada Mallarino L, Engel C, Ilik IA, Maticzka D, Heyl F, Müller B, Yakulov TA, Dengjel J, Backofen R, Akhtar A, Walz G. (2020) Nephronophthisis gene products display RNA-binding properties and are recruited to stress granules Sci Rep, doi: 10.1038/s41598-020-72905-8.
Szczurkowska J, Lee S-I, Guo A, Cwetsch AW, Khan T, Rao S, Walz G, Huber TB, Cancedda L, Pautot S and Shelly M (2020) A Localized Scaffold for cGMP Increase Is Required for Apical Dendrite Development Cell Rep, DOI: 10.1016/j.celrep.2020.03.083
Schlosser P, Li Y, Sekula P, Raffler J, Grundner-Culemann F, Pietzner M, Cheng Y, Wuttke M, Steinbrenner I, Schultheiss UT, Kotsis F, Kacprowski T, Forer L, Hausknecht B, Ekici AB, Nauck M, Völker U; GCKD Investigators, Walz G, Oefner PJ, Kronenberg F, Mohney RP, Köttgen M, Suhre K, Eckardt KU, Kastenmüller G and Köttgen A. (2020) Genetic studies of urinary metabolites illuminate mechanisms of detoxification and excretion in humans Nat Genet, doi: 10.1038/s41588-019-0567-8
Ganner A, Pfeiffer ZC, Wingendorf L, Kreis S, Klein M, Walz G and Neumann-Haefelin E. (2020) The acetyltransferase p300 regulates NRF2 stability and localization Biochem Biophys Res Commun, doi: 10.1016/j.bbrc.2020.02.006.
Butt L, Unnersjö-Jess D, Höhne M, Edwards A, Binz-Lotter J, Reilly D, Hahnfeldt R, Ziegler V, Fremter K, Rinschen MM, Helmstädter M, Ebert LK, Castrop H, Hackl MJ, Walz G, Brinkkoetter PT, Liebau MC, Tory K, Hoyer PF, Beck BB, Brismar H, Blom H, Schermer B, Benzing T. (2020) A molecular mechanism explaining albuminuria in kidney disease Nat Metab, doi: 10.1038/s42255-020-0204-y.
Därr R, Kater J, Sekula P, Bausch B, Krauss T, Bode C, Walz G, Neumann HP, Zschiedrich S. (2020) Clinical decision making in small non-functioning VHL-related incidentalomas Endocr Connect, doi: 10.1530/EC-20-0208.
Neumann-Haefelin E, Widmeier E, Bansbach J, Kaufmann K, Heinrich S, Walz G, Bürkle H, Kalbhenn J. (2020) Subcutaneous Enoxaparin Safely Facilitates Bedside Sustained Low-Efficiency Hemodialysis in Hypercoagulopathic Coronavirus Disease 2019 Patients-A Proof-of-Principle Trial Crit Care Explor, doi: 10.1097/CCE.0000000000000155.
Langhorst C, Ganner A, Schneider J, Prager EP, Walz G, Pisarski P, Jänigen B, Zschiedrich S. (2020) Long-term Follow-up of ABO-Incompatible Kidney Transplantation in Freiburg, Germany: A Single-Center Outcome Report Transplant Proc, doi: 10.1016/j.transproceed.2020.09.001.
Arnold F, Westermann L, Rieg S, Neumann-Haefelin E, Biever PM, Walz G, Kalbhenn J, Tanriver Y. (2020) Comparison of different anticoagulation strategies for renal replacement therapy in critically ill patients with COVID-19: a cohort study. BMC Nephrol, doi: 10.1186/s12882-020-02150-8.
Viau A, Kotsis F, Boehlke C, Braeg S, Klein M, Nitschke R, Walz G, Kuehn EW. (2020) Divergent function of polycystin 1 and polycystin 2 in cell size regulation. Biochem Biophys Res Commun, doi: 10.1016/j.bbrc.2019.10.074.
Yuan J, Aikawa S, Deng W, Bartos A, Walz G, Grahammer F, Huber TB, Sun X and Dey SK. (2019) Primary decidual zone formation requires Scribble for pregnancy success in mice Nat Commun, doi: 10.1038/s41467-019-13489-4.
Kampf LL, Schneider R, Gerstner L, Thünauer R, Chen M, Helmstädter M, Amar A, Onuchic-Whitford AC, Loza Munarriz R, Berdeli A, Müller D, Schrezenmeier E, Budde K, Mane S, Laricchia KM, Rehm HL, MacArthur DG, Lifton RP, Walz G, Römer W, Bergmann C, Hildebrandt F and Hermle T. (2019) TBC1D8B Mutations Implicate RAB11-Dependent Vesicular Trafficking in the Pathogenesis of Nephrotic Syndrome J Am Soc Nephrol, doi: 10.1681/ASN.2019040414.
Schuhmacher P, Kim E, Hahn F, Sekula P, Jilg CA, Leiber C, Neumann HP, Schultze-Seemann W, Walz G and Zschiedrich S. (2019) Growth characteristics and therapeutic decision markers in von Hippel-Lindau disease patients with renal cell carcinoma Orphanet J Rare Dis, doi: 10.1186/s13023-019-1206-2.
Lagies S, Pichler R, Bork T, Kaminski MM, Troendle K, Zimmermann S, Huber TB, Walz G, Lienkamp SS and Kammerer B. (2019) Impact of Diabetic Stress Conditions on Renal Cell Metabolome Cells, doi: 10.3390/cells8101141.
Ganner A, Gerber J, Ziegler AK, Li Y, Kandzia J, Matulenski T, Kreis S, Breves G, Klein M, Walz G and Neumann-Haefelin E. (2019) CBP-1/p300 acetyltransferase regulates SKN-1/Nrf cellular levels, nuclear localization, and activity in C. elegans Exp Gerontol, doi: 10.1016/j.exger.2019.110690.
Schlimpert M, Lagies S, Müller B, Budnyk V, Blanz KD, Walz G and Kammerer B. (2019) Metabolic perturbations caused by depletion of nephronophthisis factor Anks6 in mIMCD3 cells Metabolomics, doi: 10.1007/s11306-019-1535-0.
Küchlin S, Duffner J, Scheubeck S, Schoeller K, Maruschke L, Seidl M, Engelhardt M, Walz G, Prager EP and Waldschmidt JM. (2019) Kidney embolization induces prompt organ response in a 86-year-old patient with MGRS-related AL-amyloidosis Hemodial Int, doi: 10.1111/hdi.12707.
Schmidts A, Grünewald J, Kleber M, Terpos E, Ihorst G, Reinhardt H, Walz G, Wäsch R, Engelhardt M and Zschiedrich S. (2019) GFR estimation in lenalidomide treatment of multiple myeloma patients: a prospective cohort study. Clin Exp Nephrol, doi: 10.1007/s10157-018-1626-7.
Küchlin S, Duffner J, Scheubeck S, Schoeller K, Maruschke L, Seidl M, Engelhardt M, Walz G, Prager EP, Waldschmidt JM. (2018) Kidney embolization induces prompt organ response in a 86-year-old patient with MGRS-related AL-amyloidosis Hemodial Int, E59-E64
Yakulov TA, Todkar AP, Slanchev K, Wiegel J, Bona A, Groß M, Scholz A, Hess I, Wurditsch A, Grahammer F, Huber TB, Lecaudey V, Bork T, Hochrein J, Boerries M, Leenders J, de Tullio P, Jouret F, Kramer-Zucker A and Walz G. (2018) CXCL12 and MYC control energy metabolism to support adaptive responses after kidney injury Nat Commun, 3660
Schmidts A, Grünewald J, Kleber M, Terpos E, Ihorst G, Reinhardt H, Walz G, Wäsch R, Engelhardt M and Zschiedrich S. (2018) GFR estimation in lenalidomide treatment of multiple myeloma patients: a prospective cohort study Clin Exp Nephrol, 199-206
Bechtel-Walz W, Walz G and Neumann-Haefelin E. (2018) Long-Term Therapeutic Plasma Exchange Therapy as Effective Approach to Refractory Primary Acquired Pregnancy-Related Thrombocytopenic Purpura Ther Apher Dial, 99-100
Hoff S, Epting D, Falk N, Schroda S, Braun DA, Halbritter J, Hildebrandt F, Kramer-Zucker A, Bergmann C, Walz G and Lienkamp SS. (2018) The nucleoside-diphosphate kinase NME3 associates with nephronophthisis proteins and is required for ciliary function during renal development J Biol Chem, 15243-15255
Dash BP, Schnöder TM, Kathner C, Mohr J, Weinert S, Herzog C, Godavarthy PS, Zanetti C, Perner F, Braun-Dullaeus R, Hartleben B, Huber TB, Walz G, Naumann M, Ellis S, Vasioukhin V, Kähne T, Krause DS and Heidel FH. (2018) Diverging impact of cell fate determinants Scrib and Llgl1 on adhesion and migration of hematopoietic stem cells J Cancer Res Clin Oncol, 1933-1944
Hofherr A, Seger C, Fitzpatrick F, Busch T, Michel E, Luan J, Osterried L, Linden F, Kramer-Zucker A, Wakimoto B, Schütze C, Wiedemann N, Artati A, Adamski J, Walz G, Kunji ERS, Montell C, Watnick T and Köttgen M. (2018) The mitochondrial transporter SLC25A25 links ciliary TRPP2 signaling and cellular metabolism PLoS Biol, e2005651
Viau A, Bienaimé F, Lukas K, Todkar AP, Knoll M, Yakulov TA, Hofherr A, Kretz O, Helmstädter M, Reichardt W, Braeg S, Aschman T, Merkle A, Pfeifer D, Dumit VI, Gubler MC, Nitschke R, Huber TB, Terzi F, Dengjel J, Grahammer F, Köttgen M, Busch H, Boerries M, Walz G, Triantafyllopoulou A and Kuehn EW. (2018) Cilia-localized LKB1 regulates chemokine signaling, macrophage recruitment, and tissue homeostasis in the kidney EMBO J, doi: 10.15252/embj.201798615
Schlimpert M, Lagies S, Budnyk V, Müller B, Walz G and Kammerer B. (2018) Metabolic Phenotyping of Anks3 Depletion in mIMCD-3 cells - a Putative Nephronophthisis Candidate Sci Rep, doi: 10.1038/s41598-018-27389-y.
Li Y, Finkbeiner S, Ganner A, Gerber J, Klein M, Grafe M, Kandzia J, Thien A, Thedieck K, Breves G, Jank T, Baumeister R, Walz G and Neumann-Haefelin E. (2018) CGEF-1 regulates mTORC1 signaling during adult longevity and stress response in C. elegans Oncotarget, doi: 10.18632/oncotarget.24039.
Lagies S, Pichler R, Kaminski MM, Schlimpert M, Walz G, Lienkamp SS and Kammerer B. (2018) Metabolic characterization of directly reprogrammed renal tubular epithelial cells (iRECs) Sci Rep, doi: 10.1038/s41598-018-22073-7.
McEwan P, Bennett Wilton H, Ong ACM, Ørskov B, Sandford R, Scolari F, Cabrera MV, Walz G, O'Reilly K and Robinson P. (2018) A model to predict disease progression in patients with autosomal dominant polycystic kidney disease (ADPKD): the ADPKD Outcomes Model BMC Nephrol, doi: 10.1186/s12882-017-0804-2.
Welte T, Arnold F, Kappes J, Seidl M, Häffner K, Bergmann C, Walz G and Neumann-Haefelin E. (2018) Treating C3 glomerulopathy with eculizumab BMC Nephrol, doi: 10.1186/s12882-017-0802-4.
Wunnenburger S, Schultheiss UT, Walz G, Hausknecht B, Ekici AB, Kronenberg F, Eckardt KU, Köttgen A and Wuttke M. (2017) Associations between genetic risk variants for kidney diseases and kidney disease etiology Sci Rep, 13944
Kuechlin S, Schoels M, Slanchev K, Lassmann S, Walz G and Yakulov TA. (2017) EpCAM controls morphogenetic programs during zebrafish pronephros development Biochem Biophys Res Commun, 209-215
Walz G. (2017) Role of primary cilia in non-dividing and post-mitotic cells Cell Tissue Res, 11-25
Zschiedrich S, Bork T, Liang W, Wanner N, Eulenbruch K, Munder S, Hartleben B, Kretz O, Gerber S, Simons M, Viau A, Burtin M, Wei C, Reiser J, Herbach N, Rastaldi MP, Cohen CD, Tharaux PL, Terzi F, Walz G, Gödel M and Huber TB. (2017) Targeting mTOR Signaling Can Prevent the Progression of FSGS J Am Soc Nephrol, 2144-2157
Sekula P, Li Y, Stanescu HC, Wuttke M, Ekici AB, Bockenhauer D, Walz G, Powis SH, Kielstein JT, Brenchley P; GCKD Investigators, Eckardt KU, Kronenberg F, Kleta R and Köttgen A. (2017) Genetic risk variants for membranous nephropathy: extension of and association with other chronic kidney disease aetiologies. Nephrol Dial Transplant, 325-332
Kaminski MM, Tosic J, Kresbach C, Engel H, Klockenbusch J, Müller AL, Pichler R, Grahammer F, Kretz O, Huber TB, Walz G, Arnold SJ and Lienkamp SS. (2016) Direct reprogramming of fibroblasts into renal tubular epithelial cells by defined transcription factors Nat Cell Biol, 1269-1280
Dottermusch M, Lakner T, Peyman T, Klein M, Walz G and Neumann-Haefelin E (2016) Cell cycle controls stress response and longevity in C. elegans Aging (Albany NY), 2100-2126
Welte T, Arnold F, Technau-Hafsi K, Neumann-Haefelin E, Wobser R, Zschiedrich S, Walz G and Kramer-Zucker A. (2016) Successful Management of Calciphylaxis in a Kidney Transplant Patient: Case Report Transplant Direct, e70
Binder H, Kurz T, Teschner S, Kreutz C, Geyer M, Donauer J, Kraemer-Guth A, Timmer J, Schumacher M and Walz G. (2016) Dealing with prognostic signature instability: a strategy illustrated for cardiovascular events in patients with end-stage renal disease BMC Med Genomics, 43
Grahammer F, Wigge C, Schell C, Kretz O, Patrakka J, Schneider S, Klose M, Kind J, Arnold SJ, Habermann A, Bräuniger R, Rinschen MM, Völker L, Bregenzer A, Rubbenstroth D, Boerries M, Kerjaschki D, Miner JH, Walz G, Benzing T, Fornoni A, Frangakis AS and Huber TB. (2016) A flexible, multilayered protein scaffold maintains the slit in between glomerular podocytes JCI Insight, doi: 10.1172/jci.insight.86177
Shamseldin HE, Yakulov TA, Hashem A, Walz G and Alkuraya FS. (2016) ANKS3 is mutated in a family with autosomal recessive laterality defect Hum Genet, 1233-1239
Sekula P, Li Y, Stanescu HC, Wuttke M, Ekici AB, Bockenhauer D, Walz G, Powis SH, Kielstein JT, Brenchley P; GCKD Investigators, Eckardt KU, Kronenberg F, Kleta R and Köttgen A. (2016) Genetic risk variants for membranous nephropathy: extension of and association with other chronic kidney disease aetiologies Nephrol Dial Transplant, 325-332
Busch M, Nadal J, Schmid M, Paul K, Titze S, Hübner S, Köttgen A, Schultheiss UT, Baid-Agrawal S, Lorenzen J, Schlieper G, Sommerer C, Krane V, Hilge R, Kielstein JT, Kronenberg F, Wanner C, Eckardt KU, Wolf G; GCKD Study Investigators. (2016) Glycaemic control and antidiabetic therapy in patients with diabetes mellitus and chronic kidney disease - cross-sectional data from the German Chronic Kidney Disease (GCKD) cohort BMC Nephrol, 59
Grahammer F, Nesterov V, Ahmed A, Steinhardt F, Sandner L, Arnold F, Cordts T, Negrea S, Bertog M, Ruegg MA, Hall MN, Walz G, Korbmacher C, Artunc F and Huber TB. (2016) mTORC2 critically regulates renal potassium handling J Clin Invest, 1773-82
Gee HY, Sadowski CE, Aggarwal PK, Porath JD, Yakulov TA, Schueler M, Lovric S, Ashraf S, Braun DA, Halbritter J, Fang H, Airik R, Vega-Warner V, Cho KJ, Chan TA, Morris LG, ffrench-Constant C, Allen N, McNeill H, Büscher R, Kyrieleis H, Wallot M, Gaspert A, Kistler T, Milford DV, Saleem MA, Keng WT, Alexander SI, Valentini RP, Licht C, Teh JC, Bogdanovic R, Koziell A, Bierzynska A, Soliman NA, Otto EA, Lifton RP, Holzman LB, Sibinga NE, Walz G, Tufro A and Hildebrandt F. (2016) FAT1 mutations cause a glomerulotubular nephropathy Nat Commun, 10822
Zschiedrich S, Jänigen B, Dimova D, Neumann A, Seidl M, Hils S, Geyer M, Emmerich F, Kirste G, Drognitz O, Hopt UT, Walz G, Huber TB, Pisarski P and Kramer-Zucker A. (2016) One hundred ABO-incompatible kidney transplantations between 2004 and 2014: a single-centre experience Nephrol Dial Transplant, 663-71
Ramachandran H, Yakulov TA, Engel C, Müller B and Walz G. (2016) The C175R mutation alters nuclear localization and transcriptional activity of the nephronophthisis NPHP7 gene product Eur J Hum Genet, 774-8
Zschiedrich S, Budde K, Nürnberger J, Wanner C, Sommerer C, Kunzendorf U, Banas B, Hoerl WH, Obermüller N, Arns W, Pavenstädt H, Gaedeke J, Lindner TH, Faerber L, Wimmer P, Stork R, Eckardt KU and Walz G. (2016) Secreted frizzled-related protein 4 predicts progression of autosomal dominant polycystic kidney disease Nephrol Dial Transplant, 284-9
A. Thien, M. T. Prentzell, B. Holzwarth, K. Klasener, I. Kuper, C. Boehlke, A. G. Sonntag, S. Ruf, L. Maerz, R. Nitschke, S. N. Grellscheid, M. Reth, G. Walz, R. Baumeister, E. Neumann-Haefelin and K. Thedieck (2015) TSC1 Activates TGF-beta-Smad2/3 Signaling in Growth Arrest and Epithelial-to-Mesenchymal Transition Dev Cell 32, 617-30
T. A. Yakulov, T. Yasunaga, H. Ramachandran, C. Engel, B. Muller, S. Hoff, J. Dengjel, S. S. Lienkamp and G. Walz (2015) Anks3 interacts with nephronophthisis proteins and is required for normal renal development Kidney Int, doi: 10.1038/ki.2015.17
A. Dresen, S. Finkbeiner, M. Dottermusch, J. S. Beume, Y. Li, G. Walz and E. Neumann-Haefelin (2015) Caenorhabditis elegans OSM-11 signaling regulates SKN-1/Nrf during embryonic development and adult longevity and stress response Dev Biol 400, 118-31
D. Epting, K. Slanchev, C. Boehlke, S. Hoff, N. T. Loges, T. Yasunaga, L. Indorf, S. Nestel, S. S. Lienkamp, H. Omran, E. W. Kuehn, O. Ronneberger, G. Walz and A. Kramer-Zucker (2015) The Rac1 regulator ELMO controls basal body migration and docking in multiciliated cells through interaction with Ezrin Development 142, 174-84
Antignac C, Calvet JP, Germino GG, Grantham JJ, Guay-Woodford LM, Harris PC, Hildebrandt F, Peters DJ, Somlo S, Torres VE, Walz G, Zhou J, Yu AS (2015) The Future of Polycystic Kidney Disease Research-As Seen By the 12 Kaplan Awardees J Am Soc Nephrol, Ahead of print
Ong AC, Devuyst O, Knebelmann B, Walz G, ERA-EDTA Working Group for Inherited Kidney Diseases. (2015) Autosomal dominant polycystic kidney disease: the changing face of clinical management Lancet 385, 1993-2002
Ramachandran H, Herfurth K, Grosschedl R, Schäfer T, Walz G (2015) SUMOylation Blocks the Ubiquitin-Mediated Degradation of the Nephronophthisis Gene Product Glis2/NPHP7 PloS One, doi: 10.1371/journal.pone.0130275
Beck H, Titze SI, Hübner S, Busch M, Schlieper G, Schultheiss UT, Wanner C, Kronenberg F, Krane V, Eckardt KU, Köttgen A; GCKD Investigators (2015) Heart failure in a cohort of patients with chronic kidney disease: the GCKD study PLoS One, doi: 10.1371/journal.pone.0122552
Zschiedrich S, Budde K, Nürnberger J, Wanner C, Sommerer C, Kunzendorf U, Banas B, Hoerl WH, Obermüller N, Arns W, Pavenstädt H, Gaedeke J, Lindner TH, Faerber L, Wimmer P, Stork R, Eckardt KU, Walz G (2015) Secreted frizzled-related protein 4 predicts progression of autosomal dominant polycystic kidney disease Nephrol Dial Transplant, ahead of print
Yasunaga T, Hoff S, Schell C, Helmstädter M, Kretz O, Kuechlin S, Yakulov TA, Engel C, Müller B, Bensch R, Ronneberger O, Huber TB, Lienkamp SS and Walz G. (2015) The polarity protein Inturned links NPHP4 to Daam1 to control the subapical actin network in multiciliated cells J Cell Biol, doi: 10.1083/jcb.201502043.
S. Zschiedrich, K. Budde and G. Walz (2014) Effect of everolimus on polycystic liver volume in autosomal dominant polycystic kidney disease Clin Exp Nephrol, ahead of print
F. Grahammer, N. Haenisch, F. Steinhardt, L. Sander, M. Roerden, F. Arnold, T. Cordts, N. Wanner, W. Reichardt, D. Kerjaschki, M. A. Ruegg, M. N. Hall, P. Moulin, H. Busch, M. Boerries, G. Walz, F. Artunc and T. B. Huber (2014) mTORC1 maintains renal tubular homeostasis and is essential in response to ischemic stress Proc Natl Acad Sci U S A, 111, E2817-26
C. Boehlke, B. Hartleben, T. B. Huber, H. Hopfer, G. Walz and E. Neumann-Haefelin (2014) Hantavirus infection with severe proteinuria and podocyte foot-process effacement Am J Kidney Dis 64, 452-456
Q. Zhou, J. Neubauer, J. S. Kern, W. Grotz, G. Walz and T. B. Huber (2014) Calciphylaxis Lancet 383, 1067.
H. Ramachandran, T. Schafer, Y. Kim, K. Herfurth, S. Hoff, S. S. Lienkamp, A. Kramer-Zucker and G. Walz (2014) Interaction with the Bardet-Biedl Gene Product TRIM32/BBS11 Modifies the Half-life and Localization of Glis2/NPHP7 J Biol Chem 289, 8390-401.
N. Wanner, B. Hartleben, N. Herbach, M. Goedel, N. Stickel, R. Zeiser, G. Walz, M. J. Moeller, F. Grahammer and T. B. Huber (2014) Unraveling the Role of Podocyte Turnover in Glomerular Aging and Injury J Am Soc Nephrol., 4, 707-716
Y. H. Kim, D. Epting, K. Slanchev, C. Engel, G. Walz and A. Kramer-Zucker (2013) A complex of BBS1 and NPHP7 is required for cilia motility in zebrafish PLoS One 8, e72549.
C. Boehlke, F. Kotsis, B. Buchholz, C. Powelske, K. U. Eckardt, G. Walz, R. Nitschke and E. W. Kuehn (2013) Correction: Kif3a Guides Microtubular Dynamics, Migration and Lumen Formation of MDCK Cells PLoS One 8.
M. Mergen, C. Engel, B. Muller, M. Follo, T. Schafer, M. Jung and G. Walz (2013) The nephronophthisis gene product NPHP2/Inversin interacts with Aurora A and interferes with HDAC6-mediated cilia disassembly Nephrol Dial Transplant 28, 2744-53.
V. Ruf, C. Holzem, T. Peyman, G. Walz, T. K. Blackwell and E. Neumann-Haefelin (2013) TORC2 signaling antagonizes SKN-1 to induce C. elegans mesendodermal embryonic development Dev Biol 384, 214-27.
S. Hoff, J. Halbritter, D. Epting, V. Frank, T. M. Nguyen, J. van Reeuwijk, C. Boehlke, C. Schell, T. Yasunaga, M. Helmstadter, M. Mergen, E. Filhol, K. Boldt, N. Horn, M. Ueffing, E. A. Otto, T. Eisenberger, M. W. Elting, J. A. van Wijk, D. Bockenhauer, N. J. Sebire, S. Rittig, M. Vyberg, T. Ring, M. Pohl, L. Pape, T. J. Neuhaus, N. A. Elshakhs, S. J. Koon, P. C. Harris, F. Grahammer, T. B. Huber, E. W. Kuehn, A. Kramer-Zucker, H. J. Bolz, R. Roepman, S. Saunier, G. Walz, F. Hildebrandt, C. Bergmann and S. S. Lienkamp (2013) ANKS6 is a central component of a nephronophthisis module linking NEK8 to INVS and NPHP3 Nat Genet 45, 951-6.
C. Boehlke, F. Kotsis, B. Buchholz, C. Powelske, K. U. Eckardt, G. Walz, R. Nitschke and E. W. Kuehn (2013) Kif3a guides microtubular dynamics, migration and lumen formation of MDCK cells PLoS One 8, e62165.
W. Bechtel, M. Helmstadter, J. Balica, B. Hartleben, B. Kiefer, F. Hrnjic, C. Schell, O. Kretz, S. Liu, F. Geist, D. Kerjaschki, G. Walz and T. B. Huber (2013) Vps34 deficiency reveals the importance of endocytosis for podocyte homeostasis J Am Soc Nephrol 24, 727-43.
C. Schell, L. Baumhakl, S. Salou, A. C. Conzelmann, C. Meyer, M. Helmstadter, C. Wrede, F. Grahammer, S. Eimer, D. Kerjaschki, G. Walz, S. Snapper and T. B. Huber (2013) N-wasp is required for stabilization of podocyte foot processes J Am Soc Nephrol 24, 713-21.
B. Hartleben, E. Widmeier, M. Suhm, K. Worthmann, C. Schell, M. Helmstadter, T. Wiech, G. Walz, M. Leitges, M. Schiffer and T. B. Huber (2013) aPKClambda/iota and aPKCzeta contribute to podocyte differentiation and glomerular maturation J Am Soc Nephrol 24, 253-67.
S. S. Lienkamp, K. Liu, C. M. Karner, T. J. Carroll, O. Ronneberger, J. B. Wallingford and G. Walz (2012) Vertebrate kidney tubules elongate using a planar cell polarity-dependent, rosette-based mechanism of convergent extension Nat Genet 44, 1382-7.
M. Chaki, R. Airik, A. K. Ghosh, R. H. Giles, R. Chen, G. G. Slaats, H. Wang, T. W. Hurd, W. Zhou, A. Cluckey, H. Y. Gee, G. Ramaswami, C. J. Hong, B. A. Hamilton, I. Cervenka, R. S. Ganji, V. Bryja, H. H. Arts, J. van Reeuwijk, M. M. Oud, S. J. Letteboer, R. Roepman, H. Husson, O. Ibraghimov-Beskrovnaya, T. Yasunaga, G. Walz, L. Eley, J. A. Sayer, B. Schermer, M. C. Liebau, T. Benzing, S. Le Corre, I. Drummond, S. Janssen, S. J. Allen, S. Natarajan, J. F. O'Toole, M. Attanasio, S. Saunier, C. Antignac, R. K. Koenekoop, H. Ren, I. Lopez, A. Nayir, C. Stoetzel, H. Dollfus, R. Massoudi, J. G. Gleeson, S. P. Andreoli, D. G. Doherty, A. Lindstrad, C. Golzio, N. Katsanis, L. Pape, E. B. Abboud, A. A. Al-Rajhi, R. A. Lewis, H. Omran, E. Y. Lee, S. Wang, J. M. Sekiguchi, R. Saunders, C. A. Johnson, E. Garner, K. Vanselow, J. S. Andersen, J. Shlomai, G. Nurnberg, P. Nurnberg, S. Levy, A. Smogorzewska, E. A. Otto and F. Hildebrandt (2012) Exome capture reveals ZNF423 and CEP164 mutations, linking renal ciliopathies to DNA damage response signaling Cell 150, 533-48.
S. Liu, B. Hartleben, O. Kretz, T. Wiech, P. Igarashi, N. Mizushima, G. Walz and T. B. Huber (2012) Autophagy plays a critical role in kidney tubule maintenance, aging and ischemia-reperfusion injury Autophagy 8, 826-37.
B. Hartleben, E. Widmeier, N. Wanner, M. Schmidts, S. T. Kim, L. Schneider, B. Mayer, D. Kerjaschki, J. H. Miner, G. Walz and T. B. Huber (2012) Role of the polarity protein Scribble for podocyte differentiation and maintenance PLoS One 7, e36705.
K. Skouloudaki and G. Walz (2012) YAP1 recruits c-Abl to protect angiomotin-like 1 from Nedd4-mediated degradation PLoS One 7, e35735.
S. Lienkamp, A. Ganner and G. Walz (2012) Inversin, Wnt signaling and primary cilia Differentiation 83, S49-55.
R. N. Rashmi, B. Eckes, G. Glockner, M. Groth, S. Neumann, J. Gloy, L. Sellin, G. Walz, M. Schneider, I. Karakesisoglou, L. Eichinger and A. A. Noegel (2012) The nuclear envelope protein Nesprin-2 has roles in cell proliferation and differentiation during wound healing Nucleus 3, 172-86.
K. U. Eckardt, B. Barthlein, S. Baid-Agrawal, A. Beck, M. Busch, F. Eitner, A. B. Ekici, J. Floege, O. Gefeller, H. Haller, R. Hilge, K. F. Hilgers, J. T. Kielstein, V. Krane, A. Kottgen, F. Kronenberg, P. Oefner, H. U. Prokosch, A. Reis, M. Schmid, E. Schaeffner, U. T. Schultheiss, S. A. Seuchter, T. Sitter, C. Sommerer, G. Walz, C. Wanner, G. Wolf, M. Zeier and S. Titze (2012) The German Chronic Kidney Disease (GCKD) study: design and methods Nephrol Dial Transplant 27, 1454-60.
N. Wanner, F. Noutsou, R. Baumeister, G. Walz, T. B. Huber and E. Neumann-Haefelin (2011) Functional and spatial analysis of C. elegans SYG-1 and SYG-2, orthologs of the Neph/nephrin cell adhesion module directing selective synaptogenesis PLoS One 6, e23598.
M. Godel, B. Hartleben, N. Herbach, S. Liu, S. Zschiedrich, S. Lu, A. Debreczeni-Mor, M. T. Lindenmeyer, M. P. Rastaldi, G. Hartleben, T. Wiech, A. Fornoni, R. G. Nelson, M. Kretzler, R. Wanke, H. Pavenstadt, D. Kerjaschki, C. D. Cohen, M. N. Hall, M. A. Ruegg, K. Inoki, G. Walz and T. B. Huber (2011) Role of mTOR in podocyte function and diabetic nephropathy in humans and mice J Clin Invest 121, 2197-209.
K. Slanchev, M. Putz, A. Schmitt, A. Kramer-Zucker and G. Walz (2011) Nephrocystin-4 is required for pronephric duct-dependent cloaca formation in zebrafish Hum Mol Genet 20, 3119-28.
G. Walz (2011) [Organizational forms of emergency medicine from the viewpoint of hospital management. Discipline-specific or interdisciplinary?] Chirurg 82, 342-7.
M. C. Liebau, K. Hopker, R. U. Muller, I. Schmedding, S. Zank, B. Schairer, F. Fabretti, M. Hohne, M. P. Bartram, C. Dafinger, M. Hackl, V. Burst, S. Habbig, H. Zentgraf, A. Blaukat, G. Walz, T. Benzing and B. Schermer (2011) Nephrocystin-4 regulates Pyk2-induced tyrosine phosphorylation of nephrocystin-1 to control targeting to monocilia J Biol Chem 286, 14237-45.
T. B. Huber, G. Walz and E. W. Kuehn (2011) mTOR and rapamycin in the kidney: signaling and therapeutic implications beyond immunosuppression Kidney Int 79, 502-11.
M. Geyer, J. Wilpert, T. Wiech, C. Theilacker, M. Stubanus, A. Kramer-Zucker, K. G. Fischer, O. Drognitz, A. Frydrychowicz, W. Kern, G. Walz and P. Pisarski (2011) Rapidly progressive hepatic alveolar echinococcosis in an ABO-incompatible renal transplant recipient Transpl Infect Dis 13, 278-84.
G. Walz; K. Budde; K. U. Eckardt (2011) mTOR inhibitors and autosomal dominant polycystic kidney disease (authors reply) N Engl J Med 364, 287-288.
S. Lienkamp, A. Ganner, C. Boehlke, T. Schmidt, S. J. Arnold, T. Schafer, D. Romaker, J. Schuler, S. Hoff, C. Powelske, A. Eifler, C. Kronig, A. Bullerkotte, R. Nitschke, E. W. Kuehn, E. Kim, H. Burkhardt, T. Brox, O. Ronneberger, J. Gloy and G. Walz (2010) Inversin relays Frizzled-8 signals to promote proximal pronephros development Proc Natl Acad Sci U S A 107, 20388-93.
C. Boehlke, F. Kotsis, V. Patel, S. Braeg, H. Voelker, S. Bredt, T. Beyer, H. Janusch, C. Hamann, M. Godel, K. Muller, M. Herbst, M. Hornung, M. Doerken, M. Kottgen, R. Nitschke, P. Igarashi, G. Walz and E. W. Kuehn (2010) Primary cilia regulate mTORC1 activity and cell size through Lkb1 Nat Cell Biol 12, 1115-22.
G. Walz, K. Budde, M. Mannaa, J. Nurnberger, C. Wanner, C. Sommerer, U. Kunzendorf, B. Banas, W. H. Horl, N. Obermuller, W. Arns, H. Pavenstadt, J. Gaedeke, M. Buchert, C. May, H. Gschaidmeier, S. Kramer and K. U. Eckardt (2010) Everolimus in patients with autosomal dominant polycystic kidney disease N Engl J Med 363, 830-40.
T. Hermle, D. Saltukoglu, J. Grunewald, G. Walz and M. Simons (2010) Regulation of Frizzled-dependent planar polarity signaling by a V-ATPase subunit Curr Biol 20, 1269-76.
J. Wilpert, K. G. Fischer, P. Pisarski, T. Wiech, M. Daskalakis, A. Ziegler, E. Neumann-Haefelin, O. Drognitz, F. Emmerich, G. Walz and M. Geyer (2010) Long-term outcome of ABO-incompatible living donor kidney transplantation based on antigen-specific desensitization. An observational comparative analysis Nephrol Dial Transplant 25, 3778-86.
C. Boehlke, M. Bashkurov, A. Buescher, T. Krick, A. K. John, R. Nitschke, G. Walz and E. W. Kuehn (2010) Differential role of Rab proteins in ciliary trafficking: Rab23 regulates smoothened levels J Cell Sci 123, 1460-7.
E. Neumann-Haefelin, A. Kramer-Zucker, K. Slanchev, B. Hartleben, F. Noutsou, K. Martin, N. Wanner, A. Ritter, M. Godel, P. Pagel, X. Fu, A. Muller, R. Baumeister, G. Walz and T. B. Huber (2010) A model organism approach: defining the role of Neph proteins as regulators of neuron and kidney morphogenesis Hum Mol Genet 19, 2347-59.
M. Gerner, R. Haribaskar, M. Putz, J. Czerwitzki, G. Walz and T. Schafer (2010) The retinitis pigmentosa GTPase regulator interacting protein 1 (RPGRIP1) links RPGR to the nephronophthisis protein network Kidney Int 77, 891-6.
B. Hartleben, M. Godel, C. Meyer-Schwesinger, S. Liu, T. Ulrich, S. Kobler, T. Wiech, F. Grahammer, S. J. Arnold, M. T. Lindenmeyer, C. D. Cohen, H. Pavenstadt, D. Kerjaschki, N. Mizushima, A. S. Shaw, G. Walz and T. B. Huber (2010) Autophagy influences glomerular disease susceptibility and maintains podocyte homeostasis in aging mice J Clin Invest 120, 1084-96.
H. Peng, U. Lewandrowski, B. Muller, A. Sickmann, G. Walz and T. Wegierski (2010) Identification of a Protein Kinase C-dependent phosphorylation site involved in sensitization of TRPV4 channel Biochem Biophys Res Commun 391, 1721-5.
G. Walz and E. Kim (2010) Wnt signaling and rejuvenation of the adult kidney Nephrol Dial Transplant 25, 34-6.
H. Gao, Y. Wang, T. Wegierski, K. Skouloudaki, M. Putz, X. Fu, C. Engel, C. Boehlke, H. Peng, E. W. Kuehn, E. Kim, A. Kramer-Zucker and G. Walz (2010) PRKCSH/80K-H, the protein mutated in polycystic liver disease, protects polycystin-2/TRPP2 against HERP-mediated degradation Hum Mol Genet 19, 16-24.
A. Ganner, S. Lienkamp, T. Schafer, D. Romaker, T. Wegierski, T. J. Park, S. Spreitzer, M. Simons, J. Gloy, E. Kim, J. B. Wallingford and G. Walz (2009) Regulation of ciliary polarity by the APC/C Proc Natl Acad Sci U S A 106, 17799-804.
S. Teschner, P. Gerke, M. Geyer, J. Wilpert, B. Krumme, T. Benzing and G. Walz (2009) Leflunomide therapy for polyomavirus-induced allograft nephropathy: efficient BK virus elimination without increased risk of rejection Transplant Proc 41, 2533-8.
R. Haribaskar, M. Putz, B. Schupp, K. Skouloudaki, A. Bietenbeck, G. Walz and T. Schafer (2009) The planar cell polarity (PCP) protein Diversin translocates to the nucleus to interact with the transcription factor AF9 Biochem Biophys Res Commun 387, 212-7.
K. Skouloudaki, M. Puetz, M. Simons, J. R. Courbard, C. Boehlke, B. Hartleben, C. Engel, M. J. Moeller, C. Englert, F. Bollig, T. Schafer, H. Ramachandran, M. Mlodzik, T. B. Huber, E. W. Kuehn, E. Kim, A. Kramer-Zucker and G. Walz (2009) Scribble participates in Hippo signaling and is required for normal zebrafish pronephros development Proc Natl Acad Sci U S A 106, 8579-84.
H. Gao, L. K. Sellin, M. Putz, C. Nickel, M. Imgrund, P. Gerke, R. Nitschke, G. Walz and A. G. Kramer-Zucker (2009) A short carboxy-terminal domain of polycystin-1 reorganizes the microtubular network and the endoplasmic reticulum Exp Cell Res 315, 1157-70.
T. B. Huber, B. Hartleben, K. Winkelmann, L. Schneider, J. U. Becker, M. Leitges, G. Walz, H. Haller and M. Schiffer (2009) Loss of podocyte aPKClambda/iota causes polarity defects and nephrotic syndrome J Am Soc Nephrol 20, 798-806.
R. Wobser, J. Wilpert, G. Kayser, G. Walz and M. Stubanus (2009) [Disseminated histoplasmosis with involvement of mediastinum and skin in an immunocompetent patient] Dtsch Med Wochenschr 134, 589-93.
B. Rumberger, C. Kreutz, C. Nickel, M. Klein, S. Lagoutte, S. Teschner, J. Timmer, P. Gerke, G. Walz and J. Donauer (2009) Combination of immunosuppressive drugs leaves specific "fingerprint" on gene expression in vitro Immunopharmacol Immunotoxicol 31, 283-92.
T. Wegierski, D. Steffl, C. Kopp, R. Tauber, B. Buchholz, R. Nitschke, E. W. Kuehn, G. Walz and M. Kottgen (2009) TRPP2 channels regulate apoptosis through the Ca2+ concentration in the endoplasmic reticulum EMBO J 28, 490-9.
W. Reichardt, D. Romaker, A. Becker, M. Buechert, G. Walz and D. von Elverfeldt (2009) Monitoring kidney and renal cyst volumes applying MR approaches on a rapamycin treated mouse model of ADPKD MAGMA 22, 143-9.
T. Wegierski, U. Lewandrowski, B. Muller, A. Sickmann and G. Walz (2009) Tyrosine phosphorylation modulates the activity of TRPV4 in response to defined stimuli J Biol Chem 284, 2923-33.
M. Geyer, K. G. Fischer, O. Drognitz, G. Walz, P. Pisarski and J. Wilpert (2009) ABO-incompatible kidney transplantation with antigen-specific immunoadsorption and rituximab - insights and uncertainties Contrib Nephrol 162, 47-60.
D. Romaker, M. Puetz, S. Teschner, J. Donauer, M. Geyer, P. Gerke, B. Rumberger, B. Dworniczak, P. Pennekamp, B. Buchholz, H. P. Neumann, R. Kumar, J. Gloy, K. U. Eckardt and G. Walz (2009) Increased expression of secreted frizzled-related protein 4 in polycystic kidneys J Am Soc Nephrol 20, 48-56.
E. Neumann-Haefelin, W. Qi, E. Finkbeiner, G. Walz, R. Baumeister and M. Hertweck (2008) SHC-1/p52Shc targets the insulin/IGF-1 and JNK signaling pathways to modulate life span and stress response in C. elegans Genes Dev 22, 2721-35.
T. Schafer, M. Putz, S. Lienkamp, A. Ganner, A. Bergbreiter, H. Ramachandran, V. Gieloff, M. Gerner, C. Mattonet, P. G. Czarnecki, J. A. Sayer, E. A. Otto, F. Hildebrandt, A. Kramer-Zucker and G. Walz (2008) Genetic and physical interaction between the NPHP5 and NPHP6 gene products Hum Mol Genet 17, 3655-62.
M. Kottgen, B. Buchholz, M. A. Garcia-Gonzalez, F. Kotsis, X. Fu, M. Doerken, C. Boehlke, D. Steffl, R. Tauber, T. Wegierski, R. Nitschke, M. Suzuki, A. Kramer-Zucker, G. G. Germino, T. Watnick, J. Prenen, B. Nilius, E. W. Kuehn and G. Walz (2008) TRPP2 and TRPV4 form a polymodal sensory channel complex J Cell Biol 182, 437-47.
B. Hartleben, H. Schweizer, P. Lubben, M. P. Bartram, C. C. Moller, R. Herr, C. Wei, E. Neumann-Haefelin, B. Schermer, H. Zentgraf, D. Kerjaschki, J. Reiser, G. Walz, T. Benzing and T. B. Huber (2008) Neph-Nephrin proteins bind the Par3-Par6-atypical protein kinase C (aPKC) complex to regulate podocyte cell polarity J Biol Chem 283, 23033-8.
Y. Luke, H. Zaim, I. Karakesisoglou, V. M. Jaeger, L. Sellin, W. Lu, M. Schneider, S. Neumann, A. Beijer, M. Munck, V. C. Padmakumar, J. Gloy, G. Walz and A. A. Noegel (2008) Nesprin-2 Giant (NUANCE) maintains nuclear envelope architecture and composition in skin J Cell Sci 121, 1887-98.
F. Kotsis, R. Nitschke, M. Doerken, G. Walz and E. W. Kuehn (2008) Flow modulates centriole movements in tubular epithelial cells Pflugers Arch 456, 1025-35.
X. Fu, Y. Wang, N. Schetle, H. Gao, M. Putz, G. von Gersdorff, G. Walz and A. G. Kramer-Zucker (2008) The subcellular localization of TRPP2 modulates its function J Am Soc Nephrol 19, 1342-51.
C. Bergmann, M. Fliegauf, N. O. Bruchle, V. Frank, H. Olbrich, J. Kirschner, B. Schermer, I. Schmedding, A. Kispert, B. Kranzlin, G. Nurnberg, C. Becker, T. Grimm, G. Girschick, S. A. Lynch, P. Kelehan, J. Senderek, T. J. Neuhaus, T. Stallmach, H. Zentgraf, P. Nurnberg, N. Gretz, C. Lo, S. Lienkamp, T. Schafer, G. Walz, T. Benzing, K. Zerres and H. Omran (2008) Loss of nephrocystin-3 function can cause embryonic lethality, Meckel-Gruber-like syndrome, situs inversus, and renal-hepatic-pancreatic dysplasia Am J Hum Genet 82, 959-70.
T. Benzing; G. Walz (2008) Pathogenesis of nephronophthisis and medullary cystic kidney disease. Molecular and genetic basis of renal disease (edited by D. B. Mount and M. R. Pollak) Philadelphia: Saunders Elsevier.
E. W. Kuehn, M. N. Hirt, A. K. John, P. Muehlenhardt, C. Boehlke, M. Putz, A. G. Kramer-Zucker, M. Bashkurov, P. S. van de Weyer, F. Kotsis and G. Walz (2007) Kidney injury molecule 1 (Kim1) is a novel ciliary molecule and interactor of polycystin 2 Biochem Biophys Res Commun 364, 861-6.
M. Geyer, J. Donauer, P. Pisarski, O. Drognitz, C. Schulz-Huotari, U. Wisniewski, A. Gropp, H. Gobel, P. Gerke, S. Teschner, G. Walz and J. Wilpert (2007) Preemptive postoperative antigen-specific immunoadsorption in ABO-incompatible kidney transplantation: necessary or not? Transplantation 84, S40-3.
J. Wilpert, M. Geyer, S. Teschner, T. Schaefer, P. Pisarski, C. Schulz-Huotari, A. Gropp, U. Wisniewski, H. Goebel, P. Gerke, G. Walz and J. Donauer (2007) ABO-incompatible kidney transplantation-proposal of an intensified apheresis strategy for patients with high initial isoagglutinine titers J Clin Apher 22, 314-22.
E. Kim and G. Walz (2007) Sensitive cilia set up the kidney Nat Med 13, 1409-11.
U. T. Schultheiss, H. Gobel, G. von Gersdorff, M. Stubanus, G. Walz and P. Gerke (2007) Quiz page December 2007: diarrhea and anuria in a recipient of an en bloc infant kidney transplant Am J Kidney Dis 50, A41-3.
S. Clorius, K. Technau, T. Watter, E. Schwertfeger, K. G. Fischer, G. Walz and P. Gerke (2007) Nephrogenic systemic fibrosis following exposure to gadolinium-containing contrast agent Clin Nephrol 68, 249-52.
Y. Wang, X. Fu, S. Gaiser, M. Kottgen, A. Kramer-Zucker, G. Walz and T. Wegierski (2007) OS-9 regulates the transit and polyubiquitination of TRPV4 in the endoplasmic reticulum J Biol Chem 282, 36561-70.
B. Rumberger, O. Vonend, C. Kreutz, J. Wilpert, J. Donauer, K. Amann, R. Rohrbach, J. Timmer, G. Walz and P. Gerke (2007) cDNA microarray analysis of adaptive changes after renal ablation in a sclerosis-resistant mouse strain Kidney Blood Press Res 30, 377-87.
A. Ganner, Y. M. Lee, C. Busche, A. Schmitt-Graeff, J. Encke, G. Walz and P. Gerke (2007) Successful liver transplantation in a kidney and pancreas allograft recipient with fulminant herpes simplex virus type 2 hepatitis Nephrol Dial Transplant 22, 3334-7.
D. Steffl, H. Gobel, C. Groth, K. G. Fischer, W. Kuhn, G. Walz and P. Gerke (2007) Quiz page. Renal AA amyloidosis with vascular predominance, secondary to rheumatoid arthritis Am J Kidney Dis 49, A49-50.
M. Stubanus, H. Gobel, S. Rieg, G. Walz and P. Gerke (2007) Quiz page. Minimal change glomerulonephritis associated with secondary syphilis Am J Kidney Dis 49, A49-50.
J. Wilpert, M. Geyer, P. Pisarski, O. Drognitz, C. Schulz-Huotari, A. Gropp, H. Goebel, P. Gerke, S. Teschner, G. Walz and J. Donauer (2007) On-demand strategy as an alternative to conventionally scheduled post-transplant immunoadsorptions after ABO-incompatible kidney transplantation Nephrol Dial Transplant 22, 3048-51.
E. W. Kuehn, G. Walz and T. Benzing (2007) Von hippel-lindau: a tumor suppressor links microtubules to ciliogenesis and cancer development Cancer Res 67, 4537-40.
T. Benzing, M. Simons and G. Walz (2007) Wnt signaling in polycystic kidney disease J Am Soc Nephrol 18, 1389-98.
E. W. Kuehn and G. Walz (2007) Prime time for polycystic kidney disease: does one shot of roscovitine bring the cure? Nephrol Dial Transplant 22, 2133-5.
F. Kotsis, R. Nitschke, C. Boehlke, M. Bashkurov, G. Walz and E. W. Kuehn (2007) Ciliary calcium signaling is modulated by kidney injury molecule-1 (Kim1) Pflugers Arch 453, 819-29.
U. Klingmuller, A. Bauer, S. Bohl, P. J. Nickel, K. Breitkopf, S. Dooley, S. Zellmer, C. Kern, I. Merfort, T. Sparna, J. Donauer, G. Walz, M. Geyer, C. Kreutz, M. Hermes, F. Gotschel, A. Hecht, D. Walter, L. Egger, K. Neubert, C. Borner, M. Brulport, W. Schormann, C. Sauer, F. Baumann, R. Preiss, S. MacNelly, P. Godoy, E. Wiercinska, L. Ciuclan, J. Edelmann, K. Zeilinger, M. Heinrich, U. M. Zanger, R. Gebhardt, T. Maiwald, R. Heinrich, J. Timmer, F. von Weizsacker and J. G. Hengstler (2006) Primary mouse hepatocytes for systems biology approaches: a standardized in vitro system for modelling of signal transduction pathways Syst Biol (Stevenage) 153, 433-47.
T. Wegierski, K. Hill, M. Schaefer and G. Walz (2006) The HECT ubiquitin ligase AIP4 regulates the cell surface expression of select TRP channels EMBO J 25, 5659-69.
B. Schermer, C. Ghenoiu, M. Bartram, R. U. Muller, F. Kotsis, M. Hohne, W. Kuhn, M. Rapka, R. Nitschke, H. Zentgraf, M. Fliegauf, H. Omran, G. Walz and T. Benzing (2006) The von Hippel-Lindau tumor suppressor protein controls ciliogenesis by orienting microtubule growth J Cell Biol 175, 547-54.
T. B. Huber, B. Schermer, R. U. Muller, M. Hohne, M. Bartram, A. Calixto, H. Hagmann, C. Reinhardt, F. Koos, K. Kunzelmann, E. Shirokova, D. Krautwurst, C. Harteneck, M. Simons, H. Pavenstadt, D. Kerjaschki, C. Thiele, G. Walz, M. Chalfie and T. Benzing (2006) Podocin and MEC-2 bind cholesterol to regulate the activity of associated ion channels Proc Natl Acad Sci U S A 103, 17079-86.
P. S. van de Weyer, M. Muehlfeit, C. Klose, J. V. Bonventre, G. Walz and E. W. Kuehn (2006) A highly conserved tyrosine of Tim-3 is phosphorylated upon stimulation by its ligand galectin-9 Biochem Biophys Res Commun 351, 571-6.
P. Gerke, T. Benzing, M. Hohne, A. Kispert, M. Frotscher, G. Walz and O. Kretz (2006) Neuronal expression and interaction with the synaptic protein CASK suggest a role for Neph1 and Neph2 in synaptogenesis J Comp Neurol 498, 466-75.
M. Simons and G. Walz (2006) Polycystic kidney disease: cell division without a c(l)ue? Kidney Int 70, 854-64.
X. Fang, M. B. Zeisel, J. Wilpert, B. Gissler, R. Thimme, C. Kreutz, T. Maiwald, J. Timmer, W. V. Kern, J. Donauer, M. Geyer, G. Walz, E. Depla, F. von Weizsacker, H. E. Blum and T. F. Baumert (2006) Host cell responses induced by hepatitis C virus binding Hepatology 43, 1326-36.
G. Walz (2006) Therapeutic approaches in autosomal dominant polycystic kidney disease (ADPKD): is there light at the end of the tunnel? Nephrol Dial Transplant 21, 1752-7.
J. A. Sayer, E. A. Otto, J. F. O'Toole, G. Nurnberg, M. A. Kennedy, C. Becker, H. C. Hennies, J. Helou, M. Attanasio, B. V. Fausett, B. Utsch, H. Khanna, Y. Liu, I. Drummond, I. Kawakami, T. Kusakabe, M. Tsuda, L. Ma, H. Lee, R. G. Larson, S. J. Allen, C. J. Wilkinson, E. A. Nigg, C. Shou, C. Lillo, D. S. Williams, B. Hoppe, M. J. Kemper, T. Neuhaus, M. A. Parisi, I. A. Glass, M. Petry, A. Kispert, J. Gloy, A. Ganner, G. Walz, X. Zhu, D. Goldman, P. Nurnberg, A. Swaroop, M. R. Leroux and F. Hildebrandt (2006) The centrosomal protein nephrocystin-6 is mutated in Joubert syndrome and activates transcription factor ATF4 Nat Genet 38, 674-81.
S. Teschner, M. Geyer, J. Wilpert, E. Schwertfeger, T. Schenk, G. Walz and J. Donauer (2006) Remission of polyomavirus-induced graft nephropathy treated with low-dose leflunomide Nephrol Dial Transplant 21, 2039-40.
J. Donauer, J. Wilpert, M. Geyer, E. Schwertfeger, G. Kirste, O. Drognitz, G. Walz and P. Pisarski (2006) ABO-incompatible kidney transplantation using antigen-specific immunoadsorption and rituximab: a single center experience Xenotransplantation 13, 108-10.
T. Benzing and G. Walz (2006) Cilium-generated signaling: a cellular GPS? Curr Opin Nephrol Hypertens 15, 245-9.
J. M. Shillingford, N. S. Murcia, C. H. Larson, S. H. Low, R. Hedgepeth, N. Brown, C. A. Flask, A. C. Novick, D. A. Goldfarb, A. Kramer-Zucker, G. Walz, K. B. Piontek, G. G. Germino and T. Weimbs (2006) The mTOR pathway is regulated by polycystin-1, and its inhibition reverses renal cystogenesis in polycystic kidney disease Proc Natl Acad Sci U S A 103, 5466-71.
G. Schieren, B. Rumberger, M. Klein, C. Kreutz, J. Wilpert, M. Geyer, D. Faller, J. Timmer, I. Quack, L. C. Rump, G. Walz and J. Donauer (2006) Gene profiling of polycystic kidneys Nephrol Dial Transplant 21, 1816-24.
M. Horndasch, S. Lienkamp, E. Springer, A. Schmitt, H. Pavenstadt, G. Walz and J. Gloy (2006) The C/EBP homologous protein CHOP (GADD153) is an inhibitor of Wnt/TCF signals Oncogene 25, 3397-407.
G. Walz (2006) Cell and molecular biology in medicine: Basic science and clinical relevance in the example of autosomal polycystic kidney diseases. Fortschritte in der Inneren Medizin.
B. Schermer, K. Hopker, H. Omran, C. Ghenoiu, M. Fliegauf, A. Fekete, J. Horvath, M. Kottgen, M. Hackl, S. Zschiedrich, T. B. Huber, A. Kramer-Zucker, H. Zentgraf, A. Blaukat, G. Walz and T. Benzing (2005) Phosphorylation by casein kinase 2 induces PACS-1 binding of nephrocystin and targeting to cilia EMBO J 24, 4415-24.
G. Walz (2005) Slit or pore? A mutation of the ion channel TRPC6 causes FSGS Nephrol Dial Transplant 20, 1777-9.
M. Kottgen and G. Walz (2005) Subcellular localization and trafficking of polycystins Pflugers Arch 451, 286-93.
M. Simons, J. Gloy, A. Ganner, A. Bullerkotte, M. Bashkurov, C. Kronig, B. Schermer, T. Benzing, O. A. Cabello, A. Jenny, M. Mlodzik, B. Polok, W. Driever, T. Obara and G. Walz (2005) Inversin, the gene product mutated in nephronophthisis type II, functions as a molecular switch between Wnt signaling pathways Nat Genet 37, 537-43.
P. Gerke, L. Sellin, O. Kretz, D. Petraschka, H. Zentgraf, T. Benzing and G. Walz (2005) NEPH2 is located at the glomerular slit diaphragm, interacts with nephrin and is cleaved from podocytes by metalloproteinases J Am Soc Nephrol 16, 1693-702.
P. S. Goerttler, C. Kreutz, J. Donauer, D. Faller, T. Maiwald, E. Marz, B. Rumberger, T. Sparna, A. Schmitt-Graff, J. Wilpert, J. Timmer, G. Walz and H. L. Pahl (2005) Gene expression profiling in polycythaemia vera: overexpression of transcription factor NF-E2 Br J Haematol 129, 138-50.
M. Kottgen, T. Benzing, T. Simmen, R. Tauber, B. Buchholz, S. Feliciangeli, T. B. Huber, B. Schermer, A. Kramer-Zucker, K. Hopker, K. C. Simmen, C. C. Tschucke, R. Sandford, E. Kim, G. Thomas and G. Walz (2005) Trafficking of TRPP2 by PACS proteins represents a novel mechanism of ion channel regulation EMBO J 24, 705-16.
B. Buchholz, R. Tauber, D. Steffl, G. Walz and M. Kottgen (2004) An inwardly rectifying whole cell current induced by Gq-coupled receptors Biochem Biophys Res Commun 322, 177-85.
F. Jochimsen, W. Gruening, T. Arnould, M. S. Segal, M. S. Kruskall, R. Colgrove, Jr. and G. Walz (2004) Thrombotic microangiopathy associated with unusual viral sequences in HIV-1-positive patients Nephrol Dial Transplant 19, 1129-35.
T. B. Huber, M. Simons, B. Hartleben, L. Sernetz, M. Schmidts, E. Gundlach, M. A. Saleem, G. Walz and T. Benzing (2003) Molecular basis of the functional podocin-nephrin complex: mutations in the NPHS2 gene disrupt nephrin targeting to lipid raft microdomains Hum Mol Genet 12, 3397-405.
G. Walz (2003) [Pathogenetic aspectics of nephrotic syndrome] Internist (Berl) 44, 1075-82.
J. Donauer, B. Rumberger, M. Klein, D. Faller, J. Wilpert, T. Sparna, G. Schieren, R. Rohrbach, P. Dern, J. Timmer, P. Pisarski, G. Kirste and G. Walz (2003) Expression profiling on chronically rejected transplant kidneys Transplantation 76, 539-47.
E. A. Otto, B. Schermer, T. Obara, J. F. O'Toole, K. S. Hiller, A. M. Mueller, R. G. Ruf, J. Hoefele, F. Beekmann, D. Landau, J. W. Foreman, J. A. Goodship, T. Strachan, A. Kispert, M. T. Wolf, M. F. Gagnadoux, H. Nivet, C. Antignac, G. Walz, I. A. Drummond, T. Benzing and F. Hildebrandt (2003) Mutations in INVS encoding inversin cause nephronophthisis type 2, linking renal cystic disease to the function of primary cilia and left-right axis determination Nat Genet 34, 413-20.
H. Olbrich, M. Fliegauf, J. Hoefele, A. Kispert, E. Otto, A. Volz, M. T. Wolf, G. Sasmaz, U. Trauer, R. Reinhardt, R. Sudbrak, C. Antignac, N. Gretz, G. Walz, B. Schermer, T. Benzing, F. Hildebrandt and H. Omran (2003) Mutations in a novel gene, NPHP3, cause adolescent nephronophthisis, tapeto-retinal degeneration and hepatic fibrosis Nat Genet 34, 455-9.
T. B. Huber, B. Hartleben, J. Kim, M. Schmidts, B. Schermer, A. Keil, L. Egger, R. L. Lecha, C. Borner, H. Pavenstadt, A. S. Shaw, G. Walz and T. Benzing (2003) Nephrin and CD2AP associate with phosphoinositide 3-OH kinase and stimulate AKT-dependent signaling Mol Cell Biol 23, 4917-28.
P. Gerke, T. B. Huber, L. Sellin, T. Benzing and G. Walz (2003) Homodimerization and heterodimerization of the glomerular podocyte proteins nephrin and NEPH1 J Am Soc Nephrol 14, 918-26.
T. B. Huber, M. Schmidts, P. Gerke, B. Schermer, A. Zahn, B. Hartleben, L. Sellin, G. Walz and T. Benzing (2003) The carboxyl terminus of Neph family members binds to the PDZ domain protein zonula occludens-1 J Biol Chem 278, 13417-21.
L. Sellin, T. B. Huber, P. Gerke, I. Quack, H. Pavenstadt and G. Walz (2003) NEPH1 defines a novel family of podocin interacting proteins FASEB J 17, 115-7.
G. Walz (2002) [Pathogenesis of cystic kidney diseases] Verh Dtsch Ges Pathol 86, 138-44.
T. Benzing, M. Kottgen, M. Johnson, B. Schermer, H. Zentgraf, G. Walz and E. Kim (2002) Interaction of 14-3-3 protein with regulator of G protein signaling 7 is dynamically regulated by tumor necrosis factor-alpha J Biol Chem 277, 32954-62.
C. Nickel, T. Benzing, L. Sellin, P. Gerke, A. Karihaloo, Z. X. Liu, L. G. Cantley and G. Walz (2002) The polycystin-1 C-terminal fragment triggers branching morphogenesis and migration of tubular kidney epithelial cells J Clin Invest 109, 481-9.
T. B. Huber, M. Kottgen, B. Schilling, G. Walz and T. Benzing (2001) Interaction with podocin facilitates nephrin signaling J Biol Chem 276, 41543-6.
T. Benzing, P. Gerke, K. Hopker, F. Hildebrandt, E. Kim and G. Walz (2001) Nephrocystin interacts with Pyk2, p130(Cas), and tensin and triggers phosphorylation of Pyk2 Proc Natl Acad Sci U S A 98, 9784-9.
R. Schreiber, P. Kindle, T. Benzing, G. Walz and K. Kunzelmann (2001) Control of the cystic fibrosis transmembrane conductance regulator by alphaG(i) and RGS proteins Biochem Biophys Res Commun 281, 917-23.
D. H. Vandorpe, M. N. Chernova, L. Jiang, L. K. Sellin, S. Wilhelm, A. K. Stuart-Tilley, G. Walz and S. L. Alper (2001) The cytoplasmic C-terminal fragment of polycystin-1 regulates a Ca2+-permeable cation channel J Biol Chem 276, 4093-101.
L. M. Guay-Woodford, C. J. Wright, G. Walz and G. A. Churchill (2000) Quantitative trait loci modulate renal cystic disease severity in the mouse bpk model J Am Soc Nephrol 11, 1253-60.
T. Benzing, M. B. Yaffe, T. Arnould, L. Sellin, B. Schermer, B. Schilling, R. Schreiber, K. Kunzelmann, G. G. Leparc, E. Kim and G. Walz (2000) 14-3-3 interacts with regulator of G protein signaling proteins and modulates their activity J Biol Chem 275, 28167-72.
T. Benzing, R. Brandes, L. Sellin, B. Schermer, S. Lecker, G. Walz and E. Kim (1999) Upregulation of RGS7 may contribute to tumor necrosis factor-induced changes in central nervous function Nat Med 5, 913-8.
E. Kim, T. Arnould, L. Sellin, T. Benzing, N. Comella, O. Kocher, L. Tsiokas, V. P. Sukhatme and G. Walz (1999) Interaction between RGS7 and polycystin Proc Natl Acad Sci U S A 96, 6371-6.
S. Ananth, B. Knebelmann, W. Gruning, M. Dhanabal, G. Walz, I. E. Stillman and V. P. Sukhatme (1999) Transforming growth factor beta1 is a target for the von Hippel-Lindau tumor suppressor and a critical growth factor for clear cell renal carcinoma Cancer Res 59, 2210-6.
T. Arnould, L. Sellin, T. Benzing, L. Tsiokas, H. T. Cohen, E. Kim and G. Walz (1999) Cellular activation triggered by the autosomal dominant polycystic kidney disease gene product PKD2 Mol Cell Biol 19, 3423-34.
W. Gruning, T. Arnould, F. Jochimsen, L. Sellin, S. Ananth, E. Kim and G. Walz (1999) Modulation of renal tubular cell function by RGS3 Am J Physiol 276, F535-43.
L. Tsiokas, T. Arnould, C. Zhu, E. Kim, G. Walz and V. P. Sukhatme (1999) Specific association of the gene product of PKD2 with the TRPC1 channel Proc Natl Acad Sci U S A 96, 3934-9.
E. Kim, T. Arnould, L. K. Sellin, T. Benzing, M. J. Fan, W. Gruning, S. Y. Sokol, I. Drummond and G. Walz (1999) The polycystic kidney disease 1 gene product modulates Wnt signaling J Biol Chem 274, 4947-53.
M. J. Fan, W. Gruning, G. Walz and S. Y. Sokol (1998) Wnt signaling and transcriptional control of Siamois in Xenopus embryos Proc Natl Acad Sci U S A 95, 5626-31.
T. Arnould, E. Kim, L. Tsiokas, F. Jochimsen, W. Gruning, J. D. Chang and G. Walz (1998) The polycystic kidney disease 1 gene product mediates protein kinase C alpha-dependent and c-Jun N-terminal kinase-dependent activation of the transcription factor AP-1 J Biol Chem 273, 6013-8.
L. Tsiokas, E. Kim, T. Arnould, V. P. Sukhatme and G. Walz (1997) Homo- and heterodimeric interactions between the gene products of PKD1 and PKD2 Proc Natl Acad Sci U S A 94, 6965-70.
H. Haller, U. Kunzendorf, K. Sacherer, C. Lindschau, G. Walz, A. Distler and F. C. Luft (1997) T cell adhesion to P-selectin induces tyrosine phosphorylation of pp125 focal adhesion kinase and other substrates J Immunol 158, 1061-7.
U. Kunzendorf, T. Pohl, S. Bulfone-Paus, H. Krause, M. Notter, A. Onu, G. Walz and T. Diamantstein (1996) Suppression of cell-mediated and humoral immune responses by an interleukin-2-immunoglobulin fusion protein in mice J Clin Invest 97, 1204-10.
C. Wanner, W. Bartens, G. Walz, M. Nauck and P. Schollmeyer (1995) Protein loss and genetic polymorphism of apolipoprotein(a) modulate serum lipoprotein(a) in CAPD patients Nephrol Dial Transplant 10, 75-81.
U. Kunzendorf, S. Kruger-Krasagakes, M. Notter, H. Hock, G. Walz and T. Diamantstein (1994) A sialyl-Le(x)-negative melanoma cell line binds to E-selectin but not to P-selectin Cancer Res 54, 1109-12.
U. Kunzendorf, M. Notter, H. Hock, A. Distler, T. Diamantstein and G. Walz (1993) T cells bind to the endothelial adhesion molecule GMP-140 (P-selectin) Transplantation 56, 1213-7.
C. Stevens, G. Walz, C. Singaram, M. L. Lipman, B. Zanker, A. Muggia, D. Antonioli, M. A. Peppercorn and T. B. Strom (1992) Tumor necrosis factor-alpha, interleukin-1 beta, and interleukin-6 expression in inflammatory bowel disease Dig Dis Sci 37, 818-26.
U. Kunzendorf, J. Brockmoller, U. Bickel, F. Jochimsen, G. Walz, I. Roots and G. Offermann (1991) Promotion of B cell stimulation in graft recipients through a mechanism distinct from interleukin-6 gene superinduction Transplantation 51, 1312-5.
U. Kunzendorf, G. Walz, J. Brockmoeller, H. H. Neumayer, F. Jochimsen, I. Roots, G. Offermann and T. B. Strom (1991) Effects of diltiazem upon metabolism and immunosuppressive action of cyclosporine in kidney graft recipients Transplantation 52, 280-4.
G. Walz, C. Stevens, B. Zanker, L. B. Melton, S. C. Clark, M. Suthanthiran and T. B. Strom (1991) The role of interleukin-6 in mitogenic T-cell activation: detection of interleukin-2 heteronuclear RNA by polymerase chain reaction Cell Immunol 134, 511-9.
A. Aruffo, W. Kolanus, G. Walz, P. Fredman and B. Seed (1991) CD62/P-selectin recognition of myeloid and tumor cell sulfatides Cell 67, 35-44.
P. K. Sehajpal, B. Li, B. Zanker, V. K. Murthi, A. Subramaniam, V. K. Sharma, D. Estin, E. Y. Skolnik, K. J. Wieder, G. Walz and et al. (1991) The molecular basis for the synergism between the CD3/alpha beta T cell receptor and the CD2 antigen-derived signals in promoting T-cell proliferation Transplantation 51, 468-74.
D. Camerini, G. Walz, W. A. Loenen, J. Borst and B. Seed (1991) The T cell activation antigen CD27 is a member of the nerve growth factor/tumor necrosis factor receptor gene family J Immunol 147, 3165-9.
G. Walz, B. Zanker, C. Barth, K. J. Wieder, S. C. Clark and T. B. Strom (1990) Transcriptional modulation of human IL-6 gene expression by verapamil J Immunol 144, 4242-8.
F. Keller, U. Kunzendorf, G. Walz, A. Schwarz and G. Offermann (1990) Slow accumulation of cyclosporin metabolites as measured by specific and nonspecific cyclosporin RIA Int J Clin Pharmacol Ther Toxicol 28, 167-75.
G. Walz, B. Zanker, J. R. Murphy and T. B. Strom (1990) A kinetic analysis of the effects of interleukin-2 diphtheria toxin fusion protein upon activated T cells Transplantation 49, 198-201.
B. Zanker, G. Walz, K. J. Wieder and T. B. Strom (1990) Evidence that glucocorticosteroids block expression of the human interleukin-6 gene by accessory cells Transplantation 49, 183-5.
G. Walz, U. Kunzendorf, O. Josimovic-Alasevic, L. Preuschoff, A. Schwarz, F. Keller, G. Asmus, G. Offermann, T. Diamantstein and A. Distler (1990) Soluble interleukin 2 receptor and tissue polypeptide antigen serum concentrations in end-stage renal failure Nephron 56, 157-61.
G. Walz, B. Zanker, L. B. Melton, M. Suthanthiran and T. B. Strom (1990) Possible association of the immunosuppressive and B cell lymphoma-promoting properties of cyclosporine Transplantation 49, 191-4.
K. J. Wieder, G. Walz, B. Zanker, P. Sehajpal, V. K. Sharma, E. Skolnik, T. B. Strom and M. Suthanthiran (1990) Physiologic signaling in normal human T-cells: mRNA phenotyping by northern blot analysis and reverse transcription-polymerase chain reaction Cell Immunol 128, 41-51.
G. Walz, A. Aruffo, W. Kolanus, M. Bevilacqua and B. Seed (1990) Recognition by ELAM-1 of the sialyl-Lex determinant on myeloid and tumor cells Science 250, 1132-5.
B. Zanker, G. Walz, K. J. Wieder, M. Moscovitch-Lopatin, B. R. Smith and T. B. Strom (1989) Verapamil selectively inhibits expression of interleukin-2 messenger RNA in mitogen activated mononuclear blood cells Transplant Proc 21, 85-7.
F. Keller, U. Kunzendorf, G. Walz, H. Haller and G. Offermann (1989) Saturable first-pass kinetics of propranolol J Clin Pharmacol 29, 240-5.
U. Kunzendorf, F. Keller, G. Walz, H. Haller, G. Offermann, K. Borner and H. Lode (1989) Multivariate analysis of aminoglycoside levels in hemodialysis patients Chemotherapy 35, 1-6.
U. Kunzendorf, J. Brockmoller, F. Jochimsen, F. Keller, I. Roots, G. Walz and G. Offermann (1989) Cyclosporin drug monitoring: comparison of four immunoassays and HPLC Klin Wochenschr 67, 438-41.
G. Walz, B. Zanker, K. Wieder, E. Hadro, M. Moscovitch-Lopatin, B. R. Smith and T. B. Strom (1989) Similar effects of cyclosporine and verapamil on lymphokine, interleukin 2 receptor, and proto-oncogene expression Transplantation 47, 331-4.
G. Walz, B. Zanker, K. Brand, C. Waters, F. Genbauffe, J. B. Zeldis, J. R. Murphy and T. B. Strom (1989) Sequential effects of interleukin 2-diphtheria toxin fusion protein on T-cell activation Proc Natl Acad Sci U S A 86, 9485-8.
G. Walz, U. Kunzendorf, H. Haller, F. Keller, G. Offermann, O. Josimovic-Alasevic and T. Diamantstein (1989) Factors influencing the response to hepatitis B vaccination of hemodialysis patients Nephron 51, 474-7.
G. Walz, U. Kunzendorf, A. Schwarz, R. Bauer, F. Keller and G. Offermann (1988) Elevated tissue polypeptide antigen as a risk factor for carpal tunnel syndrome in haemodialyzed patients Nephron 50, 83-4.
A. Schwarz and G. Walz (1988) [Beta 2 microglobulin. 2: Dialysis-associated amyloidosis] Fortschr Med 106, 334-7.
G. Walz and A. Schwarz (1988) [Beta 2 microglobulin. 1: Physiologic significance, behavior in kidney diseases and chronic hemodialysis] Fortschr Med 106, 331-3.
U. Kunzendorf, J. Brockmoller, F. Jochimsen, F. Keller, G. Walz and G. Offermann (1988) Cyclosporin metabolites and central-nervous-system toxicity Lancet 1, 1223.
G. Walz, U. Kunzendorf, F. Keller, R. Fitzner and G. Offermann (1988) Elevated tumor markers in hemodialysis patients Am J Nephrol 8, 187-9.
G. Walz; U. Kunzendorf; R. Bauer; F. Keller; G. Offermann (1988) The relevance of tissue polypeptide antigen (TPA) in patients with end-stage renal failure. Nieren- und Hochdruckkrankheiten 17, 211-214.
G. Walz; U. Kunzendorf; F. Keller; H. H. Neumayer; G. Offermann (1988) Cyclosporine blood levels in diltiazem-treated kidney graft recipients. Clin Transplantation 2, 21-25.
U. Kunzendorf, G. Walz, H. H. Neumayer, K. Wagner, F. Keller and G. Offermann (1987) [Effect of diltiazem on blood cyclosporin levels] Klin Wochenschr 65, 1101-3.
F. Keller; G. Walz; U. Kunzendorf; G. Offermann (1987) Initial pharmacokinetics and long-term dosage of cyclosporine. Nieren- und Hochdruckkrankheiten 16, 294-296.
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