Publications

Mekahli D, Müller RU, Marlais M, Wlodkowski T, Haeberle S, de Argumedo ML, Bergmann C, Breysem L, Fladrowski C, Henske EP, Janssens P, Jouret F, Kingswood JC, Lattouf JB, Lilien M, Maleux G, Rozenberg M, Siemer S, Devuyst O, Schaefer F, Kwiatkowski DJ, Rouvière O, Bissler J. (2024) Clinical practice recommendations for kidney involvement in tuberous sclerosis complex: a consensus statement by the ERKNet Working Group for Autosomal Dominant Structural Kidney Disorders and the ERA Genes & Kidney Working Group. Nat Rev Nephrol, doi: 10.1038/s41581-024-00818-0.

Patil S, Borisov O, Scherer N, Wirth C, Schlosser P, Wuttke M, Ehret S, Hannibal L, Eckardt KU, Hunte C, Neubauer B, Köttgen A, Köttgen M. (2024) The membrane transporter SLC25A48 enables transport of choline into human mitochondria. Kidney Int, doi: 10.1016/j.kint.2024.06.022. Epub ahead of print.

Chubanov V, Köttgen M, Touyz RM, Gudermann T. (2024) TRPM channels in health and disease. Nat Rev Nephrol, doi: 10.1038/s41581-023-00777-y.

Pilz JF, Klein M, Neumann-Haefelin E, Ganner A. (2024) VHL-dependence of EHHADH Expression in a Human Renal Cell Carcinoma Cell Line. J Kidney Cancer VHL, doi: 10.15586/jkcvhl.v11i1.322.

Herr LA, Fiala GJ, Sagar, Schaffer AM, Hummel JF, Zintchenko M, Raute K, Velasco Cárdenas RM, Heizmann B, Ebert K, Fehrenbach K, Janowska I, Chan S, Tanriver Y, Minguet S, Schamel WW. (2024) Kidins220 and Aiolos promote thymic iNKT cell development by reducing TCR signals. Sci Adv, doi: 10.1126/sciadv.adj2802.

Guo H, Rogg M, Keller J, Scherzinger AK, Jäckel J, Meyer C, Sammarco A, Helmstädter M, Gorka O, Groß O, Schell C, Bechtel-Walz W. (2024) ADP-Ribosylation Factor-Interacting Protein 2 Acts as a Novel Regulator of Mitophagy and Autophagy in Podocytes in Diabetic Nephropathy. Antioxidants (Basel), doi: 10.3390/antiox13010081.

Arnold F, Kappes J, Rottmann FA, Westermann L, Welte T. (2024) HbA1c-dependent projection of long-term renal outcomes. J Intern Med, doi: 10.1111/joim.13736.

Rottmann FA, Abraham H, Welte T, Westermann L, Bemtgen X, Gauchel N, Supady A, Wengenmayer T, Staudacher DL. (2024) Atrial fibrillation and survival on a medical intensive care unit. Int J Cardiol, doi: 10.1016/j.ijcard.2023.131673.

Grahammer F, Dumoulin B, Gulieva RE, Wu H, Xu Y, Sulaimanov N, Arnold F, Sandner L, Cordts T, Todkar A, Moulin P, Reichardt W, Puelles VG, Kramann R, Freedman BS, Busch H, Boerries M, Walz G, Huber TB (2024) Cyclin-dependent kinase 4 drives cystic kidney disease in the absence of mTORC1 signaling activity Kidney Int, doi: 10.1016/j.kint.2024.08.021. Epub ahead of print.

Leroy C, Lang K, Spitz D, Milosavljevic J, Heinkele H, Kayser S, Helmstädter M, Walz G, Ulbrich MH, Hermle T (2024) Linking Basement Membrane and Slit Diaphragm in Drosophila Nephrocytes J Am Soc Nephrol, doi: 10.1681/ASN.0000000000000400. Epub ahead of print.

Matuschik L, Seifert G, Lammich K, Holzner P, Tanriver Y, Fichtner-Feigl S, Walz G, Schneider J, Jänigen B (2024) Non-antigen-specific Immunoadsorption Is a Risk Factor for Severe Postoperative Infections in ABO-Incompatible Kidney Transplant Recipients Transpl Int, doi: 10.3389/ti.2024.12263.

Yasunaga T, Wiegel J, Bergen MD, Helmstädter M, Epting D, Paolini A, Çiçek Ö, Radziwill G, Engel C, Brox T, Ronneberger O, Walentek P, Ulbrich MH, Walz G (2024) Author Correction: Microridge-like structures anchor motile cilia Nat Commun, doi: 10.1038/s41467-024-52323-4. Erratum for: Nat Commun. 2022 Apr 19;13(1):2056. doi: 10.1038/s41467-022-29741-3.

Tran U, Streets AJ, Smith D, Decker E, Kirschfink A, Izem L, Hassey JM, Rutland B, Valluru MK, Bräsen JH, Ott E, Epting D, Eisenberger T, Ong AC, Bergmann C, Wessely O (2024) BICC1 Interacts with PKD1 and PKD2 to Drive Cystogenesis in ADPKD bioRxiv [Preprint], doi: 10.1101/2024.08.27.608867.

Buffin-Meyer B, Richard J, Guigonis V, Weber S, König J, ..., Bergmann C, Schaefer F, van Eerde AM, Schanstra JP, Decramer S; HNF1B variant study group. (2024) Renal and Extrarenal Phenotypes in Patients With HNF1B Variants and Chromosome 17q12 Microdeletions Kidney Int Rep, doi: 10.1016/j.ekir.2024.05.007.

Dollfus H, Lilien MR, Maffei P, Verloes A, Muller J, Bacci GM, Cetiner M, van den Akker ELT, Grudzinska Pechhacker M, Testa F, Lacombe D, Stokman MF, Simonelli F, Gouronc A, Gavard A, van Haelst MM, Koenig J, Rossignol S, Bergmann C, Zacchia M, Leroy BP, Mosbah H, Van Eerde AM, Mekahli D, Servais A, Poitou C, Valverde D. (2024) Bardet-Biedl syndrome improved diagnosis criteria and management: Inter European Reference Networks consensus statement and recommendations Eur J Hum Genet, doi: 10.1038/s41431-024-01634-7. Epub ahead of print.

Buckley M, Terwagne C, Ganner A, Cubitt L, Brewer R, Kim DK, Kajba CM, Forrester N, Dace P, De Jonghe J, Shepherd STC, Sawyer C, McEwen M, Diederichs S, Neumann-Haefelin E, Turajlic S, Ivakine EA, Findlay GM. (2024) Saturation genome editing maps the functional spectrum of pathogenic VHL alleles. Nat Genet, doi: 10.1038/s41588-024-01800-z.

Arnold F, Kupferschmid L, Weissenborn P, Heldmann L, Hummel JF, Zareba P, Sagar, Rogg M, Schell C, Tanriver Y. (2024) Tissue-resident memory T cells break tolerance to renal autoantigens and orchestrate immune-mediated nephritis. Cell Mol Immunol, doi: 10.1038/s41423-024-01197-z.

Hoefele J, Eble J, Hermle T, Wuttke M, Schultheiss UT. (2024) Extrarenal manifestations in inherited kidney diseases. Nephrol Dial Transplant, doi: 10.1093/ndt/gfae176. Epub ahead of print.

Stamellou E, Nadal J, Hendry B, Mercer A, Bechtel-Walz W, Schiffer M, Eckardt KU, Kramann R, Moeller MJ, Floege J; GCKD study investigators. (2024) Long-term outcomes of adults with FSGS in the German Chronic Kidney Disease cohort. Clin Kidney J, doi: 10.1093/ckj/sfae131.

Stamellou E, Nadal J, Hendry B, Mercer A, Seikrit C, Bechtel-Walz W, Schmid M, Moeller MJ, Schiffer M, Eckardt KU, Kramann R, Floege J; GCKD study investigators. (2024) Long-term outcomes of patients with IgA nephropathy in the German CKD cohort. Clin Kidney J, doi: 10.1093/ckj/sfae230.

Brislinger-Engelhardt MM, Walentek P. (2024) Multiciliogenesis: Tricking the cell-cycle machinery to build hundreds of cilia. Curr Biol, doi: 10.1016/j.cub.2024.07.024.

Ganner A, Philipp A, Lagies S, Wingendorf L, Wang L, Pilz F, Welte T, Grand K, Lienkamp SS, Klein M, Kammerer B, Frew IJ, Walz G, Neumann-Haefelin E. (2023) SCD5 Regulation by VHL Affects Cell Proliferation and Lipid Homeostasis in ccRCC. Cells, doi: 10.3390/cells12060835.

Wang H, Zaiser F, Eckert P, Ruf J, Kayser N, Veenstra AC, Müller M, Haas R, Walz G, Yakulov TA. (2023) Inversin (NPHP2) and Vangl2 are required for normal zebrafish cloaca formation. doi: 10.1016/j.bbrc.2023.06.058.

Wäsch R, Strüssmann T, Wehr C, Marks R, Meyer PT, Walz G, Engelhardt M. (2023) Safe and successful CAR T-cell therapy targeting BCMA in a multiple myeloma patient requiring hemodialysis. Ann Hematol, doi: 10.1007/s00277-023-05163-z.

Tsang TH, Wiese M, Helmstädter M, Stehle T, Seyfferth J, Shvedunova M, Holz H, Walz G, Akhtar A. (2023) Transcriptional regulation by the NSL complex enables diversification of IFT functions in ciliated versus nonciliated cells. Sci Adv, doi: 10.1126/sciadv.adh5598.

Schneider J, Wobser R, Kühn W, Wagner D, Tanriver Y, Walz G. (2023) Nirmatrelvir/ritonavir treatment in SARS-CoV-2 positive kidney transplant recipients - a case series with four patients. BMC Nephrol, doi: 10.1186/s12882-023-03154-w.

Schlevogt B, Schlieper V, Krader J, Schröter R, Wagner T, Weiand M, Zibert A, Schmidt HH, Bergmann C, Nedvetsky PI, Krahn MP. (2023) A SEC61A1 variant is associated with autosomal dominant polycystic liver disease. Liver Int, doi: 10.1111/liv.15493.

Schlosser P, Scherer N, Grundner-Culemann F, Monteiro-Martins S, Haug S, Steinbrenner I, Uluvar B, Wuttke M, Cheng Y, Ekici AB, Gyimesi G, Karoly ED, Kotsis F, Mielke J, Gomez MF, Yu B, Grams ME, Coresh J, Boerwinkle E, Köttgen M, Kronenberg F, Meiselbach H, Mohney RP, Akilesh S; GCKD Investigators; Schmidts M, Hediger MA, Schultheiss UT, Eckardt KU, Oefner PJ, Sekula P, Li Y, Köttgen A. (2023) Genetic studies of paired metabolomes reveal enzymatic and transport processes at the interface of plasma and urine. Nat Genet, doi: 10.1038/s41588-023-01409-8.

Jaki L, Weigang S, Kern L, Kramme S, Wrobel AG, Grawitz AB, Nawrath P, Martin SR, Dähne T, Beer J, Disch M, Kolb P, Gutbrod L, Reuter S, Warnatz K, Schwemmle M, Gamblin SJ, Neumann-Haefelin E, Schnepf D, Welte T, Kochs G, Huzly D, Panning M, Fuchs J. (2023) Total escape of SARS-CoV-2 from dual monoclonal antibody therapy in an immunocompromised patient. Nat Commun, doi: 10.1038/s41467-023-37591-w.

Welte T, Arnold F, Westermann L, Rottmann FA, Hug MJ, Neumann-Haefelin E, Ganner A. (2023) Eculizumab as a treatment for C3 glomerulopathy: a single-center retrospective study. BMC Nephrol, doi: 10.1186/s12882-023-03058-9.

Mohl DA, Lagies S, Zodel K, Zumkeller M, Peighambari A, Ganner A, Plattner DA, Neumann-Haefelin E, Adlesic M, Frew IJ, Kammerer B. (2023) Integrated Metabolomic and Transcriptomic Analysis of Modified Nucleosides for Biomarker Discovery in Clear Cell Renal Cell Carcinoma. Cells, doi: 10.3390/cells12081102.

Thelen B, Schipperges V, Knörlein P, Hummel JF, Arnold F, Kupferschmid L, Klose CSN, Arnold SJ, Boerries M, Tanriver Y. (2023) Eomes is sufficient to regulate IL-10 expression and cytotoxic effector molecules in murine CD4+ T cells. Front Immunol, doi: 10.3389/fimmu.2023.1058267.

Vetrova AA, Kupaeva DM, Kizenko A, Lebedeva TS, Walentek P, Tsikolia N, Kremnyov SV. (2023) The evolutionary history of Brachyury genes in Hydrozoa involves duplications, divergence, and neofunctionalization. Sci Rep, doi: 10.1038/s41598-023-35979-8.

Ventrella R, Kim SK, Sheridan J, Grata A, Bresteau E, Hassan OA, Suva EE, Walentek P, Mitchell BJ. (2023) Bidirectional multiciliated cell extrusion is controlled by Notch-driven basal extrusion and Piezo1-driven apical extrusion. Development., doi: 10.1242/dev.201612.

Gopalakrishnan J, Feistel K, Friedrich BM, Grapin-Botton A, Jurisch-Yaksi N, Mass E, Mick DU, Müller RU, May-Simera H, Schermer B, Schmidts M, Walentek P, Wachten D. (2023) Emerging principles of primary cilia dynamics in controlling tissue organization and function. EMBO J, doi: 10.15252/embj.2023113891. Epub ahead of print.

Hermle T, Simons M. (2023) ER stress and slit diaphragms: is there a connection? Kidney Int, doi: 10.1016/j.kint.2023.01.028.

Guo H, Bechtel-Walz W. (2023) The Interplay of Autophagy and Oxidative Stress in the Kidney: What Do We Know? Nephron, doi: 10.1159/000531290. Epub ahead of print.

Welte T, Westermann L, Kappes J, Schramm MA, Bemtgen X, Staudacher DL, Hug MJ, Venhoff N, Arnold F. (2023) Identification of Covariates Modulating B-Cell Repopulation Kinetics in Subjects Receiving Rituximab Treatment. Arthritis Rheumatol, doi: 10.1002/art.42625. Epub ahead of print.

Grand K, Stoltz M, Rizzo L, Röck R, Kaminski MM, Salinas G, Getwan M, Naert T, Pichler R, Lienkamp SS. (2023) HNF1B Alters an Evolutionarily Conserved Nephrogenic Program of Target Genes. J Am Soc Nephrol, doi: 10.1681/ASN.2022010076.

Fiedler J, Moennig T, Hinrichs JH, Weber A, Wagner T, Hemmer T, Schröter R, Weide T, Epting D, Bergmann C, Nedvetsky P, Krahn MP. (2023) PATJ inhibits histone deacetylase 7 to control tight junction formation and cell polarity. Cell Mol Life Sci, doi: 10.1007/s00018-023-04994-3.

Riedmann H, Kayser S, Helmstädter M, Epting D, Bergmann C. (2023) Kif21a deficiency leads to impaired glomerular filtration barrier function. Sci Rep, doi: 10.1038/s41598-023-46270-1.

Riedhammer KM, Nguyen TT, Kosukcu C, Calzada-Wack J, Li Y, Batzir NA, Saygili S, Wimmers V, Kim GJ, Chrysanthou M, Bakey Z, Sofrin-Drucker E, Kraiger M, Sanz-Moreno A, Amarie OV, Rathkolb B, Klein-Rodewald T, Garrett L, Hölter SM, Seisenberger C, Haug S, Schlosser P, Marschall S, Wurst W, Fuchs H, Gailus-Durner V, Wuttke M, de Angelis MH, ?omi? J, Do?an ÖA, Özlük Y, Ta?demir M, A?ba? A, Canpolat N, Orenstein N, Çal??kan S, Weber RG, Bergmann C, Jeanpierre C, Saunier S, Lim TY, Hildebrandt F, Alhaddad B, Basel-Salmon L, Borovitz Y, Wu K, Antony D, Matschkal J, Schaaf CW, Renders L, Schmaderer C, Rogg M, Schell C, Meitinger T, Heemann U, Köttgen A, Arnold SJ, Ozaltin F, Schmidts M, Hoefele J. (2023) Implication of transcription factor FOXD2 dysfunction in syndromic congenital anomalies of the kidney and urinary tract (CAKUT). Kidney Int, doi: 10.1016/j.kint.2023.11.032.

Ott E, Hoff S, Indorf L, Ditengou FA, Müller J, Renschler G, Lienkamp SS, Kramer-Zucker A, Bergmann C, Epting D. (2023) A novel role for the chloride intracellular channel protein Clic5 in ciliary function. Sci Rep, doi: 10.1038/s41598-023-44235-y.

Mathes N, Comas M, Bleul R, Everaert K, Hermle T, Wiekhorst F, Knittel P, Sperling RA, Vidal X. (2023) Nitrogen-vacancy center magnetic imaging of Fe3O4 nanoparticles inside the gastrointestinal tract of Drosophila melanogaster. Nanoscale Adv, doi: 10.1039/d3na00684k.

Welte T, Goulois A, Stadler MB, Hess D, Soneson C, Neagu A, Azzi C, Wisser MJ, Seebacher J, Schmidt I, Estoppey D, Nigsch F, Reece-Hoyes J, Hoepfner D, Großhans H. (2023) Convergence of multiple RNA-silencing pathways on GW182/TNRC6. Mol Cell, doi: 10.1016/j.molcel.2023.06.001.

Westermann L, Rottmann FA, Hug MJ, Staudacher DL, Wobser R, Arnold F, Welte T. (2023) Clinical covariates influencing clinical outcomes in primary membranous nephropathy. BMC Nephrol, doi: 10.1186/s12882-023-03288-x. Erratum in: BMC Nephrol. 2023 Sep 3;24(1):260.

Devane J, Ott E, Olinger EG, Epting D, Decker E, Friedrich A, Bachmann N, Renschler G, Eisenberger T, Briem-Richter A, Grabhorn EF, Powell L, Wilson IJ, Rice SJ, Miles CG, Wood K; Genomics England Research Consortium, Trivedi P, Hirschfield G, Pietrobattista A, Wohler E, Mezina A, Sobreira N, Agolini E, Maggiore G, Dahmer-Heath M, Yilmaz A, Boerries M, Metzger P, Schell C, Grünewald I, Konrad M, König J, Schlevogt B, Sayer JA, Bergmann C. (2022) Progressive liver, kidney, and heart degeneration in children and adults affected by TULP3 mutations. Am J Hum Genet, doi: 10.1016/j.ajhg.2022.03.015.

Mohamed M, Tellez J, Bergmann C, Gale DP, Sayer JA, Olinger E. (2022) Pseudodominant Alport syndrome caused by pathogenic homozygous and compound heterozygous COL4A3 splicing variants. Ann Hum Genet, doi: 10.1111/ahg.12454.

Quatredeniers M, Bienaimé F, Ferri G, Isnard P, Porée E, Billot K, Birgy E, Mazloum M, Ceccarelli S, Silbermann F, Braeg S, Nguyen-Khoa T, Salomon R, Gubler MC, Kuehn EW, Saunier S, Viau A. (2022) The renal inflammatory network of nephronophthisis. Hum Mol Genet, doi: 10.1093/hmg/ddac014.

Thuenauer R, Kühn K, Guo Y, Kotsis F, Xu M, Trefzer A, Altmann S, Wehrum S, Heshmatpour N, Faust B, Landi A, Diedrich B, Dengjel J, Kuehn EW, Imberty A, Römer W. (2022) The Lectin LecB Induces Patches with Basolateral Characteristics at the Apical Membrane to Promote Pseudomonas aeruginosa Host Cell Invasion. mBio, doi: 10.1128/mbio.00819-22.

Yasunaga T, Wiegel J, Bergen MD, Helmstädter M, Epting D, Paolini A, Çiçek Ö, Radziwill G, Engel C, Brox T, Ronneberger O, Walentek P, Ulbrich MH, Walz G. (2022) Microridge-like structures anchor motile cilia. Nat Commun, doi: 10.1038/s41467-022-29741-3.

Klingbeil K, Nguyen TQ, Fahrner A, Guthmann C, Wang H, Schoels M, Lilienkamp M, Franz H, Eckert P, Walz G, Yakulov TA. (2022) Corpuscles of Stannius development requires FGF signaling. Dev Biol, doi: 10.1016/j.ydbio.2021.10.005.

Rogg M, Maier JI, Van Wymersch C, Helmstädter M, Sammarco A, Lindenmeyer M, Zareba P, Montanez E, Walz G, Werner M, Endlich N, Benzing T, Huber TB, Schell C. (2022) alpha-Parvin Defines a Specific Integrin Adhesome to Maintain the Glomerular Filtration Barrier. J Am Soc Nephrol, doi: 10.1681/ASN.2021101319.

Gerstner L, Chen M, Kampf LL, Milosavljevic J, Lang K, Schneider R, Hildebrandt F, Helmstädter M, Walz G, Hermle T. (2022) Inhibition of endoplasmic reticulum stress signaling rescues cytotoxicity of human apolipoprotein-L1 risk variants in Drosophila. Kidney Int, doi: 10.1016/j.kint.2021.12.031.

Zhang Z, Zhang F, Davis AK, Xin M, Walz G, Tian W, Zheng Y. (2022) CDC42 controlled apical-basal polarity regulates intestinal stem cell to transit amplifying cell fate transition via YAP-EGF-mTOR signaling. Cell Rep, doi: 10.1016/j.celrep.2021.110009.

Koehler S, Odenthal J, Ludwig V, Unnersjö Jess D, Höhne M, Jüngst C, Grawe F, Helmstädter M, Janku JL, Bergmann C, Hoyer PF, Hagmann HH, Walz G, Bloch W, Niessen C, Schermer B, Wodarz A, Denholm B, Benzing T, Iden S, Brinkkoetter PT. (2022) Scaffold polarity proteins Par3A and Par3B share redundant functions while Par3B acts independent of atypical protein kinase C/Par6 in podocytes to maintain the kidney filtration barrier. Kidney Int, doi: 10.1016/j.kint.2021.11.030.

Knoers N, Antignac C, Bergmann C, Dahan K, Giglio S, Heidet L, Lipska-Zietkiewicz BS, Noris M, Remuzzi G, Vargas-Poussou R, Schaefer F. (2022) Genetic testing in the diagnosis of chronic kidney disease: recommendations for clinical practice. Nephrol Dial Transplant, doi: 10.1093/ndt/gfab218.

Gimpel C, Bergmann C, Mekahli D. (2022) The wind of change in the management of autosomal dominant polycystic kidney disease in childhood. Pediatr Nephrol, doi: 10.1007/s00467-021-04974-4.

Viering D, Schlingmann KP, Hureaux M, Nijenhuis T, Mallett A, Chan MMY, van Beek A, van Eerde AM, Coulibaly JM, Vallet M, Decramer S, Pelletier S, Klaus G, Kömhoff M, Beetz R, Patel C, Shenoy M, Steenbergen EJ, Anderson G, Bongers EMHF, Bergmann C, Panneman D, Rodenburg RJ, Kleta R, Houillier P, Konrad M, Vargas-Poussou R, Knoers NVAM, Bockenhauer D, de Baaij JHF; Genomics England Research Consortium. (2022) Gitelman-Like Syndrome Caused by Pathogenic Variants in mtDNA. J Am Soc Nephrol, doi: 10.1681/ASN.2021050596.

Aypek H, Krisp C, Lu S, Liu S, Kylies D, Kretz O, Wu G, Moritz M, Amann K, Benz K, Tong P, Hu ZM, Alsulaiman SM, Khan AO, Grohmann M, Wagner T, Müller-Deile J, Schlüter H, Puelles VG, Bergmann C, Huber TB, Grahammer F. (2022) Loss of the collagen IV modifier prolyl 3-hydroxylase 2 causes thin basement membrane nephropathy. J Clin Invest, doi: 10.1172/JCI147253.

Hertz JM, Svenningsen P, Dimke H, Engelund MB, Nørgaard H, Hansen A, Marcussen N, Thiesson HC, Bergmann C, Larsen MJ. (2022) Detection of DZIP1L mutations by whole-exome sequencing in consanguineous families with polycystic kidney disease. Pediatr Nephrol, doi: 10.1007/s00467-022-05441-4.

Gimpel C, Bergmann C, Mekahli D. (2022) Correction to: The wind of change in the management of autosomal dominant polycystic kidney disease in childhood. Pediatr Nephrol, doi: 10.1007/s00467-021-05207-4. Erratum for: Pediatr Nephrol. 2022 Mar;37(3):473-487. PMID: 34426882.

Ziegler WH, Lüdiger S, Hassan F, Georgiadis ME, Swolana K, Khera A, Mertens A, Franke D, Wohlgemuth K, Dahmer-Heath M, König J, Dafinger C, Liebau MC, Cetiner M, Bergmann C, Soetje B, Haffner D. (2022) Primary URECs: a source to better understand the pathology of renal tubular epithelia in pediatric hereditary cystic kidney diseases. Orphanet J Rare Dis, doi: 10.1186/s13023-022-02265-1.

Boeckhaus J, Hoefele J, Riedhammer KM, Nagel M, Beck B, Choi M, Gollasch M, Bergmann C, Sonntag JE, Troesch V, Stock J, Gross O. (2022) Lifelong Effect of Therapy in Young Patients with the COL4A5 Alport Missense Variant p.(Gly624Asp): a Prospective Cohort Study. Nephrol Dial Transplant, doi: 10.1093/ndt/gfac006.

Münch J, Engesser M, Schönauer R, Hamm JA, Hartig C, Hantmann E, Akay G, Pehlivan D, Mitani T, Coban Akdemir Z, Tüysüz B, Shirakawa T, Dateki S, Claus LR, van Eerde AM; Genomics England Research Consortium, Smol T, Devisme L, Franquet H, Attié-Bitach T, Wagner T, Bergmann C, Höhn AK, Shril S, Pollack A, Wenger T, Scott AA, Paolucci S, Buchan J, Gabriel GC, Posey JE, Lupski JR, Petit F, McCarthy AA, Pazour GJ, Lo CW, Popp B, Halbritter J. (2022) Biallelic pathogenic variants in roundabout guidance receptor 1 associate with syndromic congenital anomalies of the kidney and urinary tract. Kidney Int, doi: 10.1016/j.kint.2022.01.028.

Epting D, Decker E, Ott E, Eisenberger T, Bader I, Bachmann N, Bergmann C. (2022) The ciliary transition zone protein TMEM218 synergistically interacts with the NPHP module and its reduced dosage leads to a wide range of syndromic ciliopathies. Hum Mol Genet, doi: 10.1093/hmg/ddac027.

Zeiser R, Warnatz K, Rosshart S, Sagar, Tanriver Y. (2022) GVHD, IBD, and primary immunodeficiencies: The gut as a target of immunopathology resulting from impaired immunity. Eur J Immunol, doi: 10.1002/eji.202149530.

Rickassel C, Gnirck AC, Shaikh N, Adamiak V, Waterhölter A, Tanriver Y, Neumann K, Huber TB, Gasteiger G, Panzer U, Turner JE. (2022) Conventional NK Cells and Type 1 Innate Lymphoid Cells Do Not Influence Pathogenesis of Experimental Glomerulonephritis. J Immunol, doi: 10.4049/jimmunol.2101012.

Tanriver U, Emmerich F, Hummel JF, Jänigen B, Panning M, Arnold F, Tanriver Y. (2022) IFNL4 rs368234815 polymorphism does not predict risk of BK virus associated nephropathy after living-donor kidney transplant: A case-control study. Clin Transplant, doi: 10.1111/ctr.14663.

Bona A, Seifert M, Thünauer R, Zodel K, Frew IJ, Römer W, Walz G, Yakulov TA. (2022) MARVEL domain containing CMTM4 affects CXCR4 trafficking. Mol Biol Cell, doi: 10.1091/mbc.E22-05-0152.

Kayser N, Zaiser F, Veenstra AC, Wang H, Göcmen B, Eckert P, Franz H, Köttgen A, Walz G, Yakulov TA. (2022) Clock genes rescue nphp mutations in zebrafish. Hum Mol Genet, doi: 10.1093/hmg/ddac160.

Spitz D, Comas M, Gerstner L, Kayser S, Helmstädter M, Walz G, Hermle T. (2022) mTOR-Dependent Autophagy Regulates Slit Diaphragm Density in Podocyte-like Drosophila Nephrocytes. Cells, doi: 10.3390/cells11132103.

Lang K, Milosavljevic J, Heinkele H, Chen M, Gerstner L, Spitz D, Kayser S, Helmstädter M, Walz G, Köttgen M, Spracklen A, Poulton J, Hermle T. (2022) Selective endocytosis controls slit diaphragm maintenance and dynamics in Drosophila nephrocytes. Elife, doi: 10.7554/eLife.79037.

Gessler S, Guthmann C, Schuler V, Lilienkamp M, Walz G, Yakulov TA. (2022) Control of Directed Cell Migration after Tubular Cell Injury by Nucleotide Signaling. Int J Mol Sci, doi: 10.3390/ijms23147870.

Milosavljevic J, Lempicki C, Lang K, Heinkele H, Kampf LL, Leroy C, Chen M, Gerstner L, Spitz D, Wang M, Knob AU, Kayser S, Helmstädter M, Walz G, Pollak MR, Hermle T. (2022) Nephrotic Syndrome Gene TBC1D8B Is Required for Endosomal Maturation and Nephrin Endocytosis in Drosophila. J Am Soc Nephrol, doi: 10.1681/ASN.2022030275.

Zhuang M, Scholz A, Walz G, Yakulov TA. (2022) Histone Deacetylases Cooperate with NF-KappaB to Support the Immediate Migratory Response after Zebrafish Pronephros Injury. Int J Mol Sci, doi: 10.3390/ijms23179582.

Eklou ND, Jänigen BM, Pisarski P, Walz G, Schneider J. (2022) Evaluation of Deceased Donor Kidney Transplantation in the Eurotransplant Senior Program in Comparison to Standard Allocation. Ann Transplant, doi: 10.12659/AOT.936514.

Bedin M, Boyer O, Servais A, Li Y, Villoing-Gaudé L, ..., Köttgen A, Andersen CBF, Bergmann C, Antignac C, Simons M. (2022) Human C-terminal CUBN variants associate with chronic proteinuria and normal renal function. J Clin Invest, doi: 10.1172/JCI161852. Erratum for: J Clin Invest. 2020 Jan 2;130(1):335-344. PMID: 35642643; PMCID: PMC9151686.

Choi M, Rübsam A, Schulz M, Decker E, Friedrich A, Schrezenmeier E, Halleck F, Eckardt KU, Bergmann C. (2022) Interstitial Nephritis: A Change in Diagnosis With Next-Generation Sequencing. Kidney Int Rep, doi: 10.1016/j.ekir.2022.01.1061.

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Westermann L, Li Y, Göcmen B, Niedermoser M, Rhein K, Jahn J, Cascante I, Schöler F, Moser N, Neubauer B, Hofherr A, Behrens YL, Göhring G, Köttgen A, Köttgen M, Busch T. (2022) Wildtype heterogeneity contributes to clonal variability in genome edited cells. Sci Rep, doi: 10.1038/s41598-022-22885-8.

Kumar P, Zadjali F, Yao Y, Köttgen M, Hofherr A, Gross KW, Mehta D, Bissler JJ. (2022) Single Gene Mutations in Pkd1 or Tsc2 Alter Extracellular Vesicle Production and Trafficking. Biology (Basel), doi: 10.3390/biology11050709.

Kirste S, Rühle A, Zschiedrich S, Schultze-Seemann W, Jilg CA, Neumann-Haefelin E, Lo SS, Grosu AL, Kim E. (2022) Stereotactic Body Radiotherapy for Renal Cell Carcinoma in Patients with Von Hippel-Lindau Disease-Results of a Prospective Trial. Cancers (Basel), doi: 10.3390/cancers14205069.

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Raina R, Chakraborty R, Sethi SK, Kumar D, Gibson K, Bergmann C. (2021) Diagnosis and Management of Renal Cystic Disease of the Newborn: Core Curriculum 2021 Am J Kidney Dis, doi: 10.1053/j.ajkd.2020.10.021.

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Gebauer E, Bechtel-Walz W, Schell C, Erbel M, Walz G, Hermle T. (2021) Development of Nivolumab/Ipilimumab-Associated Autoimmune Nephritis during Steroid Therapy. Case Rep Nephrol Dial, doi: 10.1159/000517502.

Ganner A, Pfeiffer ZC, Wingendorf L, Kreis S, Klein M, Walz G and Neumann-Haefelin E. (2020) The acetyltransferase p300 regulates NRF2 stability and localization Biochem Biophys Res Commun, doi: 10.1016/j.bbrc.2020.02.006.

Schlosser P, Li Y, Sekula P, Raffler J, Grundner-Culemann F, Pietzner M, Cheng Y, Wuttke M, Steinbrenner I, Schultheiss UT, Kotsis F, Kacprowski T, Forer L, Hausknecht B, Ekici AB, Nauck M, Völker U; GCKD Investigators, Walz G, Oefner PJ, Kronenberg F, Mohney RP, Köttgen M, Suhre K, Eckardt KU, Kastenmüller G and Köttgen A. (2020) Genetic studies of urinary metabolites illuminate mechanisms of detoxification and excretion in humans Nat Genet, doi: 10.1038/s41588-019-0567-8.

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Därr R, Kater J, Sekula P, Bausch B, Krauss T, Bode C, Walz G, Neumann HP, Zschiedrich S. (2020) Clinical decision making in small non-functioning VHL-related incidentalomas Endocr Connect, doi: 10.1530/EC-20-0208.

Estrada Mallarino L, Engel C, Ilik IA, Maticzka D, Heyl F, Müller B, Yakulov TA, Dengjel J, Backofen R, Akhtar A, Walz G. (2020) Nephronophthisis gene products display RNA-binding properties and are recruited to stress granules Sci Rep, doi: 10.1038/s41598-020-72905-8.

Neumann-Haefelin E, Widmeier E, Bansbach J, Kaufmann K, Heinrich S, Walz G, Bürkle H, Kalbhenn J. (2020) Subcutaneous Enoxaparin Safely Facilitates Bedside Sustained Low-Efficiency Hemodialysis in Hypercoagulopathic Coronavirus Disease 2019 Patients-A Proof-of-Principle Trial Crit Care Explor, doi: 10.1097/CCE.0000000000000155.

Langhorst C, Ganner A, Schneider J, Prager EP, Walz G, Pisarski P, Jänigen B, Zschiedrich S. (2020) Long-term Follow-up of ABO-Incompatible Kidney Transplantation in Freiburg, Germany: A Single-Center Outcome Report Transplant Proc, doi: 10.1016/j.transproceed.2020.09.001.

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Schönauer R, Baatz S, Nemitz-Kliemchen M, Frank V, Petzold F, Sewerin S, Popp B, Münch J, Neuber S, Bergmann C, Halbritter J. (2020) Matching clinical and genetic diagnoses in autosomal dominant polycystic kidney disease reveals novel phenocopies and potential candidate genes Genet Med, doi: 10.1038/s41436-020-0816-3.

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Arnold F, Westermann L, Rieg S, Neumann-Haefelin E, Biever PM, Walz G, Kalbhenn J, Tanriver Y. (2020) Comparison of different anticoagulation strategies for renal replacement therapy in critically ill patients with COVID-19: a cohort study. BMC Nephrol, doi: 10.1186/s12882-020-02150-8.

Epting D, Senaratne LDS, Ott E, Holmgren A, Sumathipala D, Larsen SM, Wallmeier J, Bracht D, Frikstad KM, Crowley S, Sikiric A, Barøy T, Käsmann-Kellner B, Decker E, Decker C, Bachmann N, Patzke S, Phelps IG, Katsanis N, Giles R, Schmidts M, Zucknick M, Lienkamp SS, Omran H, Davis EE, Doherty D, Strømme P, Frengen E, Bergmann C, Misceo D. (2020) Loss of CBY1 results in a ciliopathy characterized by features of Joubert syndrome. Hum Mutat, doi: 10.1002/humu.24127.

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Tasca A, Helmstädter M, Brislinger MM, Haas M, Mitchell B, Walentek P. (2020) Notch signaling induces either apoptosis or cell fate change in multiciliated cells during mucociliary tissue remodeling. Dev Cell, doi: 10.1016/j.devcel.2020.12.005.

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Jansen K, Castilho M, Aarts S, Kaminski MM, Lienkamp SS, Pichler R, Malda J, Vermonden T, Jansen J, and Masereeuw R. (2019) Fabrication of Kidney Proximal Tubule Grafts Using Biofunctionalized Electrospun Polymer Scaffolds. Macromol Biosci 19, e1800412

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Dash BP, Schnöder TM, Kathner C, Mohr J, Weinert S, Herzog C, Godavarthy PS, Zanetti C, Perner F, Braun-Dullaeus R, Hartleben B, Huber TB, Walz G, Naumann M, Ellis S, Vasioukhin V, Kähne T, Krause DS, and Heidel FH. (2018) Diverging impact of cell fate determinants Scrib and Llgl1 on adhesion and migration of hematopoietic stem cells. J Cancer Res Clin Oncol 144, 1933-1944

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Molinari E, Decker E, Mabillard H, Tellez J, Srivastava S, Raman S, Wood K, Kempf C, Alkanderi S, Ramsbottom SA, Miles CG, Johnson CA, Hildebrandt F, Bergmann C, and Sayer JA. (2018) Human urine-derived renal epithelial cells provide insights into kidney-specific alternate splicing variants. Eur J Hum Genet 26, 1791-1796

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Schlimpert M, Lagies S, Budnyk V, Müller B, Walz G, and Kammerer B. (2018) Metabolic Phenotyping of Anks3 Depletion in mIMCD-3 cells - a Putative Nephronophthisis Candidate. Sci Rep 8, 9022

Rinschen MM, Gödel M, Grahammer F, Zschiedrich S, Helmstädter M, Kretz O, Zarei M, Braun DA, Dittrich S, Pahmeyer C, Schroder P, Teetzen C, Gee H, Daouk G, Pohl M, Kuhn E, Schermer B, Küttner V, Boerries M, Busch H, Schiffer M, Bergmann C, Krüger M, Hildebrandt F, Dengjel J, Benzing T, and Huber TB. (2018) A Multi-layered Quantitative In Vivo Expression Atlas of the Podocyte Unravels Kidney Disease Candidate Genes. Cell Rep 23, 2495-2508

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Mathew NR, Baumgartner F, Braun L, ..., Tanriver Y, ..., Pearce E, Blazar BR, and Zeiser R. (2018) Erratum: Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells. Nat Med 24, 526

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Lagies S, Pichler R, Kaminski MM, Schlimpert M, Walz G, Lienkamp SS, and Kammerer B. (2018) Metabolic characterization of directly reprogrammed renal tubular epithelial cells (iRECs). Sci Rep 8, 3878

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McEwan P, Bennett Wilton H, Ong ACM, Ørskov B, Sandford R, Scolari F, Cabrera MV, Walz G, O'Reilly K, and Robinson P. (2018) A model to predict disease progression in patients with autosomal dominant polycystic kidney disease (ADPKD): the ADPKD Outcomes Model. BMC Nephrol 19, 37

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Welte T, Arnold F, Kappes J, Seidl M, Häffner K, Bergmann C, Walz G, and Neumann-Haefelin E. (2018) Treating C3 glomerulopathy with eculizumab. BMC Nephrol 19, 7

Kakar N, Horn D, Decker E, Sowada N, Kubisch C, Ahmad J, Borck G, and Bergmann C. (2018) Expanding the phenotype associated with biallelic WDR60 mutations: Siblings with retinal degeneration and polydactyly lacking other features of short rib thoracic dystrophies. Am J Med Genet A 176, 438-442

Gimpel C, Avni FE, Bergmann C, Cetiner M, Habbig S, Haffner D, König J, Konrad M, Liebau MC, Pape L, Rellensmann G, Titieni A, von Kaisenberg C, Weber S, Winyard PJD, and Schaefer F. (2018) Perinatal Diagnosis, Management, and Follow-up of Cystic Renal Diseases: A Clinical Practice Recommendation With Systematic Literature Reviews. JAMA Pediatr 172, 74-86

Rassner MP, Seidl M, Salzer U, Rajkumar SV, Epting T, Wäsch R, Neumann-Haefelin E, and Engelhardt M. (2018) Cast Nephropathy and Deceptively Low Absolute Serum Free Light Chain Levels: Resolution of a Challenging Case and Systematic Review of the Literature. Clin Lymphoma Myeloma Leuk 18, e1-e7

Klose CSN, Hummel JF, Faller L, d'Hargues Y, Ebert K, and Tanriver Y. (2018) A committed postselection precursor to natural TCRalphabeta+ intraepithelial lymphocytes. Mucosal Immunol 11, 333-344

Helmstädter M, Huber TB, and Hermle T. (2017) Using the Drosophila Nephrocyte to Model Podocyte Function and Disease. Front Pediatr 5, 262

Henique C, Bollée G, Loyer X, Grahammer F, Dhaun N, Camus M, Vernerey J, Guyonnet L, Gaillard F, Lazareth H, Meyer C, Bensaada I, Legrès L, Satoh T, Akira S, Bruneval P, Dimmeler S, Tedgui A, Karras A, Thervet E, Nochy D, Huber TB, Mesnard L, Lenoir O, Tharaux PL. (2017) Genetic and pharmacological inhibition of microRNA-92a maintains podocyte cell cycle quiescence and limits crescentic glomerulonephritis. Nat Commun 8, 1829

Rogg M, Yasuda-Yamahara M, Abed A, Dinse P, Helmstädter M, Conzelmann AC, Frimmel J, Sellung D, Biniossek ML, Kretz O, Grahammer F, Schilling O, Huber TB, and Schell C. (2017) The WD40-domain containing protein CORO2B is specifically enriched in glomerular podocytes and regulates the ventral actin cytoskeleton. Sci Rep 7, 15910

Wunnenburger S, Schultheiss UT, Walz G, Hausknecht B, Ekici AB, Kronenberg F, Eckardt KU, Köttgen A, and Wuttke M. (2017) Associations between genetic risk variants for kidney diseases and kidney disease etiology. Sci Rep 7, 13944

Friedmann D, Keller B, Harder I, Schupp J, Tanriver Y, Unger S, and Warnatz K. (2017) Preferential Reduction of Circulating Innate Lymphoid Cells Type 2 in Patients with Common Variable Immunodeficiency with Secondary Complications Is Part of a Broader Immune Dysregulation. J Clin Immunol 37, 759-769

Klein Geltink RI, O'Sullivan D, Corrado M, Bremser A, Buck MD, Buescher JM, Firat E, Zhu X, Niedermann G, Caputa G, Kelly B, Warthorst U, Rensing-Ehl A, Kyle RL, Vandersarren L, Curtis JD, Patterson AE, Lawless S, Grzes K, Qiu J, Sanin DE, Kretz O, Huber TB, Janssens S, Lambrecht BN, Rambold AS, Pearce EJ, and Pearce EL. (2017) Mitochondrial Priming by CD28. Cell 171, 385-397

Schell C, and Huber TB. (2017) The Evolving Complexity of the Podocyte Cytoskeleton. J Am Soc Nephrol 28, 3166-3174

Busch T, Köttgen M, and Hofherr A. (2017) TRPP2 ion channels: Critical regulators of organ morphogenesis in health and disease. Cell Calcium 66, 25-32

Rinschen MM, Hoppe AK, Grahammer F, Kann M, Völker LA, Schurek EM, Binz J, Höhne M, Demir F, Malisic M, Huber TB, Kurschat C, Kizhakkedathu JN, Schermer B, Huesgen PF, and Benzing T. (2017) N-Degradomic Analysis Reveals a Proteolytic Network Processing the Podocyte Cytoskeleton. J Am Soc Nephrol 28, 2867-2878

Mellows B, Mitchell R, Antonioli M, Kretz O, Chambers D, Zeuner MT, Denecke B, Musante L, Ramachandra DL, Debacq-Chainiaux F, Holthofer H, Joch B, Ray S, Widera D, David AL, Huber TB, Dengjel J, De Coppi P, and Patel K. (2017) Protein and Molecular Characterization of a Clinically Compliant Amniotic Fluid Stem Cell-Derived Extracellular Vesicle Fraction Capable of Accelerating Muscle Regeneration Through Enhancement of Angiogenesis. Stem Cells Dev 26, 1316-1333

Probst S, Daza RA, Bader N, Hummel JF, Weiß M, Tanriver Y, Hevner RF, and Arnold SJ. (2017) A dual-fluorescence reporter in the Eomes locus for live imaging and medium-term lineage tracing. Genesis 55, doi: 10.1002/dvg.23043

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Y. Matsumoto, J. La Rose, M. Lim, H. A. Adissu, N. Law, X. Mao, F. Cong, P. Mera, G. Karsenty, D. Goltzman, A. Changoor, L. Zhang, M. Stajkowski, M. D. Grynpas, C. Bergmann and R. Rottapel (2017) Ubiquitin ligase RNF146 coordinates bone dynamics and energy metabolism J Clin Invest 127, 2612-2625.

Huber TB, and Holthofer H. (2017) From genetics to personalized nephrology: kidney research at a tipping point. Cell Tissue Res 369, 1-4

Kaminski MM, Tosic J, Pichler R, Arnold SJ, and Lienkamp SS. (2017) Engineering kidney cells: reprogramming and directed differentiation to renal tissues. Cell Tissue Res 369, 185-197

Schell C, Rogg M, Suhm M, Helmstädter M, Sellung D, Yasuda-Yamahara M, Kretz O, Küttner V, Suleiman H, Kollipara L, Zahedi RP, Sickmann A, Eimer S, Shaw AS, Kramer-Zucker A, Hirano-Kobayashi M, Abe T, Aizawa S, Grahammer F, Hartleben B, Dengjel J, and Huber TB. (2017) The FERM protein EPB41L5 regulates actomyosin contractility and focal adhesion formation to maintain the kidney filtration barrier. Proc Natl Acad Sci U S A 114, E4621-E4630

H. Lu, M. C. R. Galeano, E. Ott, G. Kaeslin, P. J. Kausalya, C. Kramer, N. Ortiz-Bruchle, N. Hilger, V. Metzis, M. Hiersche, S. Y. Tay, R. Tunningley, S. Vij, A. D. Courtney, B. Whittle, E. Wuhl, U. Vester, B. Hartleben, S. Neuber, V. Frank, M. H. Little, D. Epting, P. Papathanasiou, A. C. Perkins, G. D. Wright, W. Hunziker, H. Y. Gee, E. A. Otto, K. Zerres, F. Hildebrandt, S. Roy, C. Wicking and C. Bergmann (2017) Mutations in DZIP1L, which encodes a ciliary-transition-zone protein, cause autosomal recessive polycystic kidney disease Nat Genet 49, 1025-1034.

K. Azukaitis, E. Simkova, M. A. Majid, M. Galiano, K. Benz, K. Amann, C. Bockmeyer, R. Gajjar, K. E. Meyers, H. I. Cheong, B. Lange-Sperandio, T. Jungraithmayr, V. Fremeaux-Bacchi, C. Bergmann, C. Bereczki, M. Miklaszewska, D. Csuka, Z. Prohaszka, P. Gipson, M. G. Sampson, M. Lemaire and F. Schaefer (2017) The Phenotypic Spectrum of Nephropathies Associated with Mutations in Diacylglycerol Kinase epsilon J Am Soc Nephrol.

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Kuechlin S, Schoels M, Slanchev K, Lassmann S, Walz G, and Yakulov TA. (2017) EpCAM controls morphogenetic programs during zebrafish pronephros development. Biochem Biophys Res Commun 487, 209-215

Assady S, Wanner N, Skorecki KL, and Huber TB. (2017) New Insights into Podocyte Biology in Glomerular Health and Disease. J Am Soc Nephrol 28, 1707-1715

Getwan M, and Lienkamp SS. (2017) Toolbox in a tadpole: Xenopus for kidney research. Cell Tissue Res 369, 143-157

Rinschen MM, Grahammer F, Hoppe AK, Kohli P, Hagmann H, Kretz O, Bertsch S, Höhne M, Göbel H, Bartram MP, Gandhirajan RK, Krüger M, Brinkkoetter PT, Huber TB, Kann M, Wickström SA, Benzing T, and Schermer B. (2017) YAP-mediated mechanotransduction determines the podocyte's response to damage. Sci Signal 10, doi: 10.1126/scisignal.aaf8165

Vivante A, Mann N, Yonath H, Weiss AC, Getwan M, Kaminski MM, Bohnenpoll T, Teyssier C, Chen J, Shril S, van der Ven AT, Ityel H, Schmidt JM, Widmeier E, Bauer SB, Sanna-Cherchi S, Gharavi AG, Lu W, Magen D, Shukrun R, Lifton RP, Tasic V, Stanescu HC, Cavaillès V, Kleta R, Anikster Y, Dekel B, Kispert A, Lienkamp SS, and Hildebrandt F. (2017) A Dominant Mutation in Nuclear Receptor Interacting Protein 1 Causes Urinary Tract Malformations via Dysregulation of Retinoic Acid Signaling. J Am Soc Nephrol 28, 2364-2376

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K. Ebner, F. Schaefer, M. C. Liebau and A. R. Consortium (2017) Recent Progress of the ARegPKD Registry Study on Autosomal Recessive Polycystic Kidney Disease Front Pediatr 5, 18.

Zschiedrich S, Bork T, Liang W, Wanner N, Eulenbruch K, Munder S, Hartleben B, Kretz O, Gerber S, Simons M, Viau A, Burtin M, Wei C, Reiser J, Herbach N, Rastaldi MP, Cohen CD, Tharaux PL, Terzi F, Walz G, Gödel M, and Huber TB. (2017) Targeting mTOR Signaling Can Prevent the Progression of FSGS. J Am Soc Nephrol 28, 2144-2157

Krones E, Eller K, Pollheimer MJ, Racedo S, Kirsch AH, Frauscher B, Wahlström A, Ståhlman M, Trauner M, Grahammer F, Huber TB, Wagner K, Rosenkranz AR, Marschall HU, and Fickert P. (2017) NorUrsodeoxycholic acid ameliorates cholemic nephropathy in bile duct ligated mice. J Hepatol 67, 110-119

Conti S, Perico L, Grahammer F, and Huber TB. (2017) The long journey through renal filtration: new pieces in the puzzle of slit diaphragm architecture. Curr Opin Nephrol Hypertens 26, 148-153

Nkuipou-Kenfack E, Schanstra JP, Bajwa S, Pejchinovski M, Vinel C, Dray C, Valet P, Bascands JL, Vlahou A, Koeck T, Borries M, Busch H, Bechtel-Walz W, Huber TB, Rudolph KL, Pich A, Mischak H, and Zürbig P. (2017) The use of urinary proteomics in the assessment of suitability of mouse models for ageing. PLoS One 12, e0166875

Hofherr A, Busch T, Huber N, Nold A, Bohn A, Viau A, Bienaimé F, Kuehn EW, Arnold SJ, and Köttgen M. (2017) Efficient genome editing of differentiated renal epithelial cells. Pflugers Arch 469, 303-311

Hermle T, Braun DA, Helmstädter M, Huber TB, and Hildebrandt F. (2017) Modeling Monogenic Human Nephrotic Syndrome in the Drosophila Garland Cell Nephrocyte. J Am Soc Nephrol 28, 1521-1533

Lee HW, Khan SQ, Khaliqdina S, Altintas MM, Grahammer F, Zhao JL, Koh KH, Tardi NJ, Faridi MH, Geraghty T, Cimbaluk DJ, Susztak K, Moita LF, Baltimore D, Tharaux PL, Huber TB, Kretzler M, Bitzer M, Reiser J, and Gupta V. (2017) Absence of miR-146a in Podocytes Increases Risk of Diabetic Glomerulopathy via Up-regulation of ErbB4 and Notch-1. J Biol Chem 292, 732-747

N. Bachmann, R. Crazzolara, F. Bohne, D. Kotzot, K. Maurer, T. Enklaar, D. Prawitt and C. Bergmann (2017) Novel deletion in 11p15.5 imprinting center region 1 in a patient with Beckwith-Wiedemann syndrome provides insight into distal enhancer regulation and tumorigenesis Pediatr Blood Cancer 64.

Sekula P, Li Y, Stanescu HC, Wuttke M, Ekici AB, Bockenhauer D, Walz G, Powis SH, Kielstein JT, Brenchley P, GCKD Investigators, Eckardt KU, Kronenberg F, Kleta R, and Köttgen A. (2017) Genetic risk variants for membranous nephropathy: extension of and association with other chronic kidney disease aetiologies. Nephrol Dial Transplant 32, 325-332

Grahammer F, Ramakrishnan SK, Rinschen MM, Larionov AA, Syed M, Khatib H, Roerden M, Sass JO, Helmstaedter M, Osenberg D, Kühne L, Kretz O, Wanner N, Jouret F, Benzing T, Artunc F, Huber TB, and Theilig F. (2017) mTOR Regulates Endocytosis and Nutrient Transport in Proximal Tubular Cells. J Am Soc Nephrol 28, 230-241

Kaminski MM, Tosic J, Kresbach C, Engel H, Klockenbusch J, Müller AL, Pichler R, Grahammer F, Kretz O, Huber TB, Walz G, Arnold SJ, and Lienkamp SS. (2016) Direct reprogramming of fibroblasts into renal tubular epithelial cells by defined transcription factors. Nat Cell Biol 18, 1269-1280

J. Munch, M. Grohmann, T. H. Lindner, C. Bergmann and J. Halbritter (2016) Diagnosing FSGS without kidney biopsy - a novel INF2-mutation in a family with ESRD of unknown origin BMC Med Genet 17, 73.

Ni J, Bao S, Johnson RI, Zhu B, Li J, Vadaparampil J, Smith CM, Campbell KN, Grahammer F, Huber TB, He JC, D'Agati VD, Chan A, and Kaufman L. (2016) MAGI-1 Interacts with Nephrin to Maintain Slit Diaphragm Structure through Enhanced Rap1 Activation in Podocytes. J Biol Chem 291, 24406-24417

Dottermusch M, Lakner T, Peyman T, Klein M, Walz G, and Neumann-Haefelin E. (2016) Cell cycle controls stress response and longevity in C. elegans. Aging (Albany NY) 8, 2100-2126

Welte T, Arnold F, Technau-Hafsi K, Neumann-Haefelin E, Wobser R, Zschiedrich S, Walz G, and Kramer-Zucker A. (2016) Successful Management of Calciphylaxis in a Kidney Transplant Patient: Case Report. Transplant Direct 2, e70

Omairi S, Matsakas A, Degens H, Kretz O, Hansson KA, Solbrå AV, Bruusgaard JC, Joch B, Sartori R, Giallourou N, Mitchell R, Collins-Hooper H, Foster K, Pasternack A, Ritvos O, Sandri M, Narkar V, Swann JR, Huber TB, and Patel K. (2016) Enhanced exercise and regenerative capacity in a mouse model that violates size constraints of oxidative muscle fibres. Elife 5, doi: 10.7554/eLife.16940

Pedigo CE, Ducasa GM, Leclercq F, Sloan A, Mitrofanova A, Hashmi T, Molina-David J, Ge M, Lassenius MI, Forsblom C, Lehto M, Groop PH, Kretzler M, Eddy S, Martini S, Reich H, Wahl P, Ghiggeri G, Faul C, Burke GW 3rd, Kretz O, Huber TB, Mendez AJ, Merscher S, and Fornoni A. (2016) Local TNF causes NFATc1-dependent cholesterol-mediated podocyte injury. J Clin Invest 126, 3336-50

Fantus D, Rogers NM, Grahammer F, Huber TB, and Thomson AW. (2016) Roles of mTOR complexes in the kidney: implications for renal disease and transplantation. Nat Rev Nephrol 12, 587-609

Binder H, Kurz T, Teschner S, Kreutz C, Geyer M, Donauer J, Kraemer-Guth A, Timmer J, Schumacher M, and Walz G. (2016) Dealing with prognostic signature instability: a strategy illustrated for cardiovascular events in patients with end-stage renal disease. BMC Med Genomics 9, 43

Grahammer F, Wigge C, Schell C, Kretz O, Patrakka J, Schneider S, Klose M, Kind J, Arnold SJ, Habermann A, Bräuniger R, Rinschen MM, Völker L, Bregenzer A, Rubbenstroth D, Boerries M, Kerjaschki D, Miner JH, Walz G, Benzing T, Fornoni A, Frangakis AS, and Huber TB. (2016) A flexible, multilayered protein scaffold maintains the slit in between glomerular podocytes. JCI Insight 1, doi: 10.1172/jci.insight.86177

Shamseldin HE1, Yakulov TA2, Hashem A3, Walz G2, Alkuraya FS4,5. (2016) ANKS3 is mutated in a family with autosomal recessive laterality defect. Hum Genet 135, 1233-1239

Grahammer F, and Huber TB. (2016) Aberrant podocyte cell cycle in glomerular disease. Cell Cycle 15, 2237-8

I. Bader, E. Decker, J. A. Mayr, V. Lunzer, J. Koch, E. Boltshauser, W. Sperl, P. Pietsch, B. Ertl-Wagner, H. Bolz, C. Bergmann and O. Rittinger (2016) MKS1 mutations cause Joubert syndrome with agenesis of the corpus callosum Eur J Med Genet 59, 386-91.

R. Anders, M. Grohmann, T. H. Lindner, C. Bergmann and J. Halbritter (2016) [Hemolytic kidney failure and transient ischemic attack in a 32-year-old female] Internist (Berl) 57, 1022-1028.

Lenoir O, Tharaux PL, and Huber TB. (2016) Autophagy in kidney disease and aging: lessons from rodent models. Kidney Int 90, 950-964

Mihalas AB, Elsen GE, Bedogni F, Daza RAM, Ramos-Laguna KA, Arnold SJ, and Hevner RF. (2016) Intermediate Progenitor Cohorts Differentially Generate Cortical Layers and Require Tbr2 for Timely Acquisition of Neuronal Subtype Identity. Cell Rep 16, 92-105

Buck MD, O'Sullivan D, Klein Geltink RI, Curtis JD, Chang CH, Sanin DE, Qiu J, Kretz O, Braas D, van der Windt GJ, Chen Q, Huang SC, O'Neill CM, Edelson BT, Pearce EJ, Sesaki H, Huber TB, Rambold AS, and Pearce EL. (2016) Mitochondrial Dynamics Controls T Cell Fate through Metabolic Programming. Cell 166, 63-76

Busch M, Nadal J, Schmid M, Paul K, Titze S, Hübner S, Köttgen A, Schultheiss UT, Baid-Agrawal S, Lorenzen J, Schlieper G, Sommerer C, Krane V, Hilge R, Kielstein JT, Kronenberg F, Wanner C, Eckardt KU, Wolf G, GCKD Study Investigators. (2016) Glycaemic control and antidiabetic therapy in patients with diabetes mellitus and chronic kidney disease - cross-sectional data from the German Chronic Kidney Disease (GCKD) cohort. BMC Nephrol 17, 59

T. Ahlenstiel-Grunow, S. Hachmeister, F. C. Bange, C. Wehling, M. Kirschfink, C. Bergmann and L. Pape (2016) Systemic complement activation and complement gene analysis in enterohaemorrhagic Escherichia coli-associated paediatric haemolytic uraemic syndrome Nephrol Dial Transplant 31, 1114-21.

Hofherr A, and Köttgen M. (2016) Polycystic kidney disease: Cilia and mechanosensation revisited. Nat Rev Nephrol 12, 318-9

C. Bergmann, V. Frank and R. Salonen (2016) Clinical utility gene card for: Meckel syndrome - update 2016 Eur J Hum Genet 24.

Trepiccione F, Gerber SD, Grahammer F, López-Cayuqueo KI, Baudrie V, Paunescu TG, Capen DE, Picard N, Alexander RT, Huber TB, Chambrey R, Brown D, Houillier P, Eladari D, and Simons M. (2016) Renal Atp6ap2/(Pro)renin Receptor Is Required for Normal Vacuolar H+-ATPase Function but Not for the Renin-Angiotensin System. J Am Soc Nephrol 27, 3320-3330

Grahammer F, Nesterov V, Ahmed A, Steinhardt F, Sandner L, Arnold F, Cordts T, Negrea S, Bertog M, Ruegg MA, Hall MN, Walz G, Korbmacher C, Artunc F, and Huber TB. (2016) mTORC2 critically regulates renal potassium handling. J Clin Invest 126, 1773-82

Hofherr A, Wagner CJ, Watnick T, and Köttgen M. (2016) Targeted rescue of a polycystic kidney disease mutation by lysosomal inhibition. Kidney Int 89, 949-55

Tharaux PL, and Huber TB. (2016) How Is Proteinuric Diabetic Nephropathy Caused by Disturbed Proteostasis and Autophagy in Podocytes? Diabetes 65, 539-41

Gee HY, Sadowski CE, Aggarwal PK, ..., Walz G, Tufro A, and Hildebrandt F. (2016) FAT1 mutations cause a glomerulotubular nephropathy. Nat Commun 7, 10822

A. O. Khan, E. Decker, N. Bachmann, H. J. Bolz and C. Bergmann (2016) C8orf37 is mutated in Bardet-Biedl syndrome and constitutes a locus allelic to non-syndromic retinal dystrophies Ophthalmic Genet 37, 290-3.

Lienkamp SS. (2016) Using Xenopus to study genetic kidney diseases. Semin Cell Dev Biol 51, 117-24

Rinschen MM, Bharill P, Wu X, Kohli P, Reinert MJ, Kretz O, Saez I, Schermer B, Höhne M, Bartram MP, Aravamudhan S, Brooks BR, Vilchez D, Huber TB, Müller RU, Krüger M, and Benzing T. (2016) The ubiquitin ligase Ubr4 controls stability of podocin/MEC-2 supercomplexes. Hum Mol Genet 25, 1328-44

S. Habbig, C. Bergmann and L. T. Weber (2016) Discontinuation of Eculizumab in a Patient With Atypical Hemolytic Uremic Syndrome Due to a Mutation in CFH Am J Kidney Dis 67, 532-3.

Schell C, Kretz O, Liang W, Kiefer B, Schneider S, Sellung D, Bork T, Leiber C, Rüegg MA, Mallidis C, Schlatt S, Mayerhofer A, Huber TB, and Grahammer F. (2016) The Rapamycin-Sensitive Complex of Mammalian Target of Rapamycin Is Essential to Maintain Male Fertility. Am J Pathol 186, 324-36

Zschiedrich S, Jänigen B, Dimova D, Neumann A, Seidl M, Hils S, Geyer M, Emmerich F, Kirste G, Drognitz O, Hopt UT, Walz G, Huber TB, Pisarski P, and Kramer-Zucker A. (2016) One hundred ABO-incompatible kidney transplantations between 2004 and 2014: a single-centre experience. Nephrol Dial Transplant 31, 663-71

Lother A, Fürst D, Bergemann S, Gilsbach R, Grahammer F, Huber TB, Hilgendorf I, Bode C, Moser M, and Hein L. (2016) Deoxycorticosterone Acetate/Salt-Induced Cardiac But Not Renal Injury Is Mediated By Endothelial Mineralocorticoid Receptors Independently From Blood Pressure. Hypertension 67, 130-8

Wuttke M, Wong CS, Wühl E, Epting D, Luo L, Hoppmann A, Doyon A, Li Y, CKDGen Consortium, Sözeri B, Thurn D, Helmstädter M, Huber TB, Blydt-Hansen TD, Kramer-Zucker A, Mehls O, Melk A, Querfeld U, Furth SL, Warady BA, Schaefer F, and Köttgen A. (2016) Genetic loci associated with renal function measures and chronic kidney disease in children: the Pediatric Investigation for Genetic Factors Linked with Renal Progression Consortium. Nephrol Dial Transplant 31, 262-9

Villarreal R, Mitrofanova A, Maiguel D, Morales X, Jeon J, Grahammer F, Leibiger IB, Guzman J, Fachado A, Yoo TH, Busher Katin A, Gellermann J, Merscher S, Burke GW, Berggren PO, Oh J, Huber TB, and Fornoni A. (2016) Nephrin Contributes to Insulin Secretion and Affects Mammalian Target of Rapamycin Signaling Independently of Insulin Receptor. J Am Soc Nephrol 27, 1029-41

Sheikh BN, Bechtel-Walz W, Lucci J, Karpiuk O, Hild I, Hartleben B, Vornweg J, Helmstädter M, Sahyoun AH, Bhardwaj V, Stehle T, Diehl S, Kretz O, Voss AK, Thomas T, Manke T, Huber TB, and Akhtar A. (2016) MOF maintains transcriptional programs regulating cellular stress response. Oncogene 35, 2698-710

Ramachandran H, Yakulov TA, Engel C, Müller B, and Walz G. (2016) The C175R mutation alters nuclear localization and transcriptional activity of the nephronophthisis NPHP7 gene product. Eur J Hum Genet 24, 774-8

E. Korkmaz, B. S. Lipska-Zietkiewicz, O. Boyer, O. Gribouval, C. Fourrage, M. Tabatabaei, S. Schnaidt, S. Gucer, F. Kaymaz, M. Arici, A. Dinckan, S. Mir, A. K. Bayazit, S. Emre, A. Balat, L. Rees, R. Shroff, C. Bergmann, C. Mourani, C. Antignac, F. Ozaltin, F. Schaefer and C. PodoNet (2016) ADCK4-Associated Glomerulopathy Causes Adolescence-Onset FSGS J Am Soc Nephrol 27, 63-8.

W. R. Cnossen, R. H. te Morsche, A. Hoischen, C. Gilissen, H. Venselaar, S. Mehdi, C. Bergmann, M. Losekoot, M. H. Breuning, D. J. Peters, J. A. Veltman and J. P. Drenth (2016) LRP5 variants may contribute to ADPKD Eur J Hum Genet 24, 237-42.

Zschiedrich S, Budde K, Nürnberger J, Wanner C, Sommerer C, Kunzendorf U, Banas B, Hoerl WH, Obermüller N, Arns W, Pavenstädt H, Gaedeke J, Lindner TH, Faerber L, Wimmer P, Stork R, Eckardt KU, and Walz G. (2016) Secreted frizzled-related protein 4 predicts progression of autosomal dominant polycystic kidney disease. Nephrol Dial Transplant 31, 284-9

C. Boehlke, H. Janusch, C. Hamann, C. Powelske, M. Mergen, H. Herbst, F. Kotsis, R. Nitschke, EW. Kuehn (2015) A Cilia Independent Role of Ift88/Polaris during Cell Migration PloS One 10, e0140378- e0140378

Burke BT, Köttgen A, Law A, Windham BG, Segev D, Baer AN, Coresh J, McAdams-DeMarco MA (2015) Physical function, hyperuricemia and gout in older adults enrolled in the atherosclerosis risk in communities cohort study Arthritis Care Res, doi: 10.1002/acr.22648

Khan AO, Al Rashaed S, Neuhaus C, Bergmann C, Bolz HJ (2015) Peripherin mutations cause a distinct form of recessive Leber congenital amaurosis and dominant phenotypes in asymptomatic parents heterozygous for the mutation Br J Ophtalmol, pii: bjophthalmol-2015-306844

Tin A, Köttgen A, Folsom AR, Maruthur NM, Tajuddin SM, Nalls MA, Evans MK, Zonderman AB, Friedrich CA, Boerwinkle E, Coresh J, Kao WH (2015) Genetic loci for serum magnesium among African-Americans and gene-environment interaction at MUC1 and TRPM6 in European-Americans: the Atherosclerosis Risk in Communities (ARIC) study BMC Genet 16, doi: 10.1186/s12863-015-0219-7

Chen YC, Auer-Grumbach M, Matsukawa S, Zitzelsberger M, Themistocleous AC, Strom TM, Samara C, Moore AW, Cho LT, Young GT, Weiss C, Schabhüttl M, Stucka R, Schmid AB, Parman Y, Graul-Neumann L, Heinritz W, Passarge E, Watson RM, Hertz JM, Moog U, Baumgartner M, Valente EM, Pereira D, Restrepo CM, Katona I, Dusl M, Stendel C, Wieland T, Stafford F, Reimann F, von Au K, Finke C, Willems PJ28, Nahorski MS1, Shaikh SS, Carvalho OP, Nicholas AK, Karbani G, McAleer MA, Cilio MR, McHugh JC, Murphy SM, Irvine AD, Jensen UB, Windhager R, Weis J, Bergmann C, Rautenstrauss B, Baets J, De Jonghe P, Reilly MM, Kropatsch R, Kurth I, Chrast R, Michiue T, Bennett DL, Woods CG, Senderek J (2015) Transcriptional regulator PRDM12 is essential for human pain perception Nat Genet 47, 803-808

Verbitsky M, Sanna-Cherchi S, Fasel DA, Levy B, Kiryluk K, Wuttke M, Abraham AG, Kaskel F, Köttgen A, Warady BA, Furth SL, Wong CS, Gharavi AG (2015) Genomic imbalances in pediatric patients with chronic kidney disease J Clin Invest 125, 2171-2178

Ebner K, Feldkoetter M, Ariceta G, Bergmann C, Buettner R, Doyon A, Duzova A, Goebel H, Haffner D, Hero B, Hoppe B, Illig T, Jankauskiene A, Klopp N, König J, Litwin M, Mekahli D, Ranchin B, Sander A, Testa S, Weber LT, Wicher D, Yuzbasioglu A, Zerres K, Dötsch J, Schaefer F, Liebau MC29; ESCAPE Study Group; GPN Study Group (2015) Rationale, design and objectives of ARegPKD, a European ARPKD registry study BMC Nephrol, doi: 10.1186/s12882-015-0002-z

Lehnhardt A, Karnatz C, Ahlenstiel-Grunow T, Benz K, Benz MR, Budde K, Büscher AK, Fehr T, Feldkötter M, Graf N, Höcker B, Jungraithmayr T, Klaus G, Koehler B, Konrad M, Kranz B, Montoya CR, Müller D, Neuhaus TJ, Oh J, Pape L, Pohl M, Royer-Pokora B, Querfeld U, Schneppenheim R, Staude H, Spartà G, Timmermann K, Wilkening F, Wygoda S, Bergmann C, Kemper MJ (2015) Clinical and molecular characterization of patients with heterozygous mutations in wilms tumor suppressor gene 1 Clin J Am Soc Nephrol, 10, 825-831

Huffman JE, Albrecht E, Teumer A, Mangino M, Kapur K, Johnson T, Kutalik Z, Pirastu N, Pistis G, Lopez LM, Haller T, Salo P, Goel A, Li M, Tanaka T, Dehghan A, Ruggiero D, Malerba G, Smith AV, Nolte IM, Portas L, Phipps-Green A, Boteva L, Navarro P, Johansson A, Hicks AA, Polasek O, Esko T, Peden JF, Harris SE, Murgia F, Wild SH, Tenesa A, Tin A, Mihailov E, Grotevendt A, Gislason GK, Coresh J, D'Adamo P, Ulivi S, Vollenweider P, Waeber G, Campbell S, Kolcic I, Fisher K, Viigimaa M, Metter JE, Masciullo C, Trabetti E, Bombieri C, Sorice R, Döring A, Reischl E, Strauch K, Hofman A, Uitterlinden AG, Waldenberger M, Wichmann HE, Davies G, Gow AJ, Dalbeth N, Stamp L, Smit JH, Kirin M, Nagaraja R, Nauck M, Schurmann C, Budde K, Farrington SM, Theodoratou E, Jula A, Salomaa V, Sala C, Hengstenberg C, Burnier M, Mägi R, Klopp N, Kloiber S, Schipf S, Ripatti S, Cabras S, Soranzo N, Homuth G, Nutile T, Munroe PB, Hastie N, Campbell H, Rudan I, Cabrera C, Haley C, Franco OH, Merriman TR, Gudnason V, Pirastu M, Penninx BW, Snieder H, Metspalu A, Ciullo M, Pramstaller PP, van Duijn CM, Ferrucci L, Gambaro G, Deary IJ, Dunlop MG, Wilson JF, Gasparini P, Gyllensten U, Spector TD, Wright AF, Hayward C, Watkins H, Perola M, Bochud M, Kao WH, Caulfield M, Toniolo D, Völzke H, Gieger C, Köttgen A, Vitart V (2015) Modulation of genetic associations with serum urate levels by body-mass-index in humans PLos One 10, e0119752

A. B. Chapman, O. Devuyst, K. U. Eckardt, R. T. Gansevoort, T. Harris, S. Horie, B. L. Kasiske, D. Odland, Y. Pei, R. D. Perrone, Y. Pirson, R. W. Schrier, R. Torra, V. E. Torres, T. Watnick, D. C. Wheeler and P. Conference (2015) Autosomal-dominant polycystic kidney disease (ADPKD): executive summary from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference Kidney Int 88, 17-27.

W. Dondorp, G. de Wert, Y. Bombard, D. W. Bianchi, C. Bergmann, P. Borry, L. S. Chitty, F. Fellmann, F. Forzano, A. Hall, L. Henneman, H. C. Howard, A. Lucassen, K. Ormond, B. Peterlin, D. Radojkovic, W. Rogowski, M. Soller, A. Tibben, L. Tranebjaerg, C. G. van El and M. C. Cornel (2015) Non-invasive prenatal testing for aneuploidy and beyond: challenges of responsible innovation in prenatal screening Eur J Hum Genet, doi: 10.1038/ejhg.2015.57

M. Godel, F. Grahammer and T. B. Huber (2015) Thrombospondin type-1 domain-containing 7A in idiopathic membranous nephropathy N Engl J Med 372, 1073

M. Thoenes, U. Zimmermann, I. Ebermann, M. Ptok, M. A. Lewis, H. Thiele, S. Morlot, M. M. Hess, A. Gal, T. Eisenberger, C. Bergmann, G. Nurnberg, P. Nurnberg, K. P. Steel, M. Knipper and H. Bolz (2015) OSBPL2 encodes a protein of inner and outer hair cell stereocilia and is mutated in autosomal dominant hearing loss (DFNA67) Orphanet J Rare Dis 10

G. Schalk, M. Kirschfink, C. Wehling, S. Gastoldi, C. Bergmann, B. Hoppe and L. T. Weber (2015) A complicated case of atypical hemolytic uremic syndrome with frequent relapses under eculizumab Pediatr Nephrol

Powell JJ, Thomas-McKay E, Thoree V, Robertson J, Hewitt RE, Skepper JN, Brown A, Hernandez-Garrido JC, Midgley PA, Gomez-Morilla I, Grime GW, Kirkby KJ, Mabbott NA, Donaldson DS, Williams IR, Rios D, Girardin SE, Haas CT, Bruggraber SF, Laman JD, Tanriver Y, Lombardi G, Lechler R, Thompson RP, Pele LC (2015) An endogenous nanomineral chaperones luminal antigen and peptidoglycan to intestinal immune cells Nat Nanotechnol 10, 361-369

A. Thien, M. T. Prentzell, B. Holzwarth, K. Klasener, I. Kuper, C. Boehlke, A. G. Sonntag, S. Ruf, L. Maerz, R. Nitschke, S. N. Grellscheid, M. Reth, G. Walz, R. Baumeister, E. Neumann-Haefelin and K. Thedieck (2015) TSC1 Activates TGF-beta-Smad2/3 Signaling in Growth Arrest and Epithelial-to-Mesenchymal Transition Dev Cell 32, 617-30

U. T. Schultheiss, A. Teumer, M. Medici, Y. Li, N. Daya, L. Chaker, G. Homuth, A. G. Uitterlinden, M. Nauck, A. Hofman, E. Selvin, H. Volzke, R. P. Peeters and A. Kottgen (2015) A Genetic Risk Score for Thyroid Peroxidase Antibodies Associates with Clinical Thyroid Disease in Community-Based Populations J Clin Endocrinol Metab, jc20144352

K. I. Greenberg, M. A. McAdams-DeMarco, A. Kottgen, L. J. Appel, J. Coresh and M. E. Grams (2015) Plasma Urate and Risk of a Hospital Stay with AKI: The Atherosclerosis Risk in Communities Study Clin J Am Soc Nephrol

F. Grahammer, T. Benzing and T. B. Huber (2015) New insights into mechanisms of glomerular injury and repair from the 10th International Podocyte Conference Kidney Int, doi: 10.1038/ki.2015.5

M. C. Funk, A. N. Bera, T. Menchen, G. Kuales, K. Thriene, S. S. Lienkamp, J. Dengjel, H. Omran, M. Frank and S. J. Arnold (2015) Cyclin O (Ccno) functions during deuterosome-mediated centriole amplification of multiciliated cells Embo J 34, 1078-89

T. A. Yakulov, T. Yasunaga, H. Ramachandran, C. Engel, B. Muller, S. Hoff, J. Dengjel, S. S. Lienkamp and G. Walz (2015) Anks3 interacts with nephronophthisis proteins and is required for normal renal development Kidney Int, doi: 10.1038/ki.2015.17

T. Eisenberger, C. Decker, M. Hiersche, R. C. Hamann, E. Decker, S. Neuber, V. Frank, H. J. Bolz, H. Fehrenbach, L. Pape, B. Toenshoff, C. Mache, K. Latta and C. Bergmann (2015) An efficient and comprehensive strategy for genetic diagnostics of polycystic kidney disease PLoS One 10, e0116680

A. Dresen, S. Finkbeiner, M. Dottermusch, J. S. Beume, Y. Li, G. Walz and E. Neumann-Haefelin (2015) Caenorhabditis elegans OSM-11 signaling regulates SKN-1/Nrf during embryonic development and adult longevity and stress response Dev Biol 400, 118-31

D. Epting, K. Slanchev, C. Boehlke, S. Hoff, N. T. Loges, T. Yasunaga, L. Indorf, S. Nestel, S. S. Lienkamp, H. Omran, E. W. Kuehn, O. Ronneberger, G. Walz and A. Kramer-Zucker (2015) The Rac1 regulator ELMO controls basal body migration and docking in multiciliated cells through interaction with Ezrin Development 142, 174-84

Gorski M, Tin A, Garnaas M, McMahon GM, Chu AY, Tayo BO, Pattaro C, Teumer A, Chasman DI, Chalmers J, Hamet P, Tremblay J, Woodward M, Aspelund T, Eiriksdottir G, Gudnason V, Harris TB, Launer LJ, Smith AV, Mitchell BD, O'Connell JR, Shuldiner AR, Coresh J, Li M, Freudenberger P, Hofer E, Schmidt H, Schmidt R, Holliday EG, Mitchell P, Wang JJ, de Boer IH, Li G, Siscovick DS, Kutalik Z, Corre T, Vollenweider P, Waeber G, Gupta J, Kanetsky PA, Hwang SJ, Olden M, Yang Q, de Andrade M, Atkinson EJ, Kardia SL, Turner ST, Stafford JM, Ding J, Liu Y, Barlassina C, Cusi D, Salvi E, Staessen JA, Ridker PM, Grallert H, Meisinger C, Müller-Nurasyid M, Krämer BK, Kramer H, Rosas SE, Nolte IM, Penninx BW, Snieder H, Fabiola Del Greco M, Franke A, Nöthlings U, Lieb W, Bakker SJ, Gansevoort RT, van der Harst P, Dehghan A, Franco OH, Hofman A, Rivadeneira F, Sedaghat S, Uitterlinden AG, Coassin S, Haun M, Kollerits B, Kronenberg F, Paulweber B, Aumann N, Endlich K, Pietzner M, Völker U, Rettig R, Chouraki V, Helmer C, Lambert JC, Metzger M, Stengel B, Lehtimäki T, Lyytikäinen LP, Raitakari O, Johnson A, Parsa A, Bochud M, Heid IM, Goessling W, Köttgen A, Kao WH, Fox CS, Böger CA. (2015) Genome-wide association study of kidney function decline in individuals of European descent Kidney Int 87, 1017-1029

A. O. Khan, C. Bergmann, C. Neuhaus and H. J. Bolz (2015) A Distinct Vitreo-retinal Dystrophy with Early-onset Cataract from Recessive KCNJ13 Mutations Ophthalmic Genet 36, 79-84

M. Wuttke, F. Schaefer, C. S. Wong and A. Kottgen (2015) Genome-wide association studies in nephrology: using known associations for data checks Am J Kidney Dis 65, 217-22

Jing J, Kielstein JT, Schultheiss UT, Sitter T, Titze SI, Schaeffner ES, McAdams-DeMarco M, Kronenberg F, Eckardt KU, Köttgen A; GCKD Study Investigators (2015) Prevalence and correlates of gout in a large cohort of patients with chronic kidney disease: the German Chronic Kidney Disease (GCKD) study Nephrol Dial Transplant 30, 613-621

S. Zschiedrich, A. Kramer-Zucker, B. Janigen, M. Seidl, F. Emmerich, P. Pisarski and T. B. Huber (2015) An update on ABO-incompatible kidney transplantation Transpl Int 28, 387-97

S. Titze, M. Schmid, A. Kottgen, M. Busch, J. Floege, C. Wanner, F. Kronenberg and K. U. Eckardt (2015) Disease burden and risk profile in referred patients with moderate chronic kidney disease: composition of the German Chronic Kidney Disease (GCKD) cohor Nephrol Dial Transplant 30, 441-51

M. J. Janssen, J. Salomon, W. R. Cnossen, C. Bergmann, R. Pfundt and J. P. Drenth (2015) Somatic loss of polycystic disease genes contributes to the formation of isolated and polycystic liver cysts Gut 64, 688-90

C. Bergmann (2015) ARPKD and early manifestations of ADPKD: the original polycystic kidney disease and phenocopies Pediatr Nephrol 30, 15-30

Antignac C, Calvet JP, Germino GG, Grantham JJ, Guay-Woodford LM, Harris PC, Hildebrandt F, Peters DJ, Somlo S, Torres VE, Walz G, Zhou J, Yu AS (2015) The Future of Polycystic Kidney Disease Research-As Seen By the 12 Kaplan Awardees J Am Soc Nephrol, Ahead of print

Ramachandran H, Herfurth K, Grosschedl R, Schäfer T, Walz G (2015) SUMOylation Blocks the Ubiquitin-Mediated Degradation of the Nephronophthisis Gene Product Glis2/NPHP7 PloS One, doi: 10.1371/journal.pone.0130275

Ong AC, Devuyst O, Knebelmann B, Walz G, ERA-EDTA Working Group for Inherited Kidney Diseases. (2015) Autosomal dominant polycystic kidney disease: the changing face of clinical management Lancet 385, 1993-2002

Huppke P, Wegener E, Böhrer-Rabel H, Bolz HJ, Zoll B, Gärtner J, Bergmann C (2015) Tectonic gene mutations in patients with Joubert syndrome Eur J Hum Genet 5, 616-6120

Ling G, Landau D, Bergmann C, Maor E, Yerushalmi B. (2015) Neonatal ascites in autosomal recessive polycystic kidney disease (ARPKD) Clin Nephrol 83, 297-300

Beck H, Titze SI, Hübner S, Busch M, Schlieper G, Schultheiss UT, Wanner C, Kronenberg F, Krane V, Eckardt KU, Köttgen A; GCKD Investigators (2015) Heart failure in a cohort of patients with chronic kidney disease: the GCKD study PLoS One, doi: 10.1371/journal.pone.0122552

Zschiedrich S, Budde K, Nürnberger J, Wanner C, Sommerer C, Kunzendorf U, Banas B, Hoerl WH, Obermüller N, Arns W, Pavenstädt H, Gaedeke J, Lindner TH, Faerber L, Wimmer P, Stork R, Eckardt KU, Walz G (2015) Secreted frizzled-related protein 4 predicts progression of autosomal dominant polycystic kidney disease Nephrol Dial Transplant, ahead of print

EW. Kuehn, G. Walz (2015) Therapy of ADPKD Dtsch. Ärtzeblatt

Yasunaga T, Hoff S, Schell C, Helmstädter M, Kretz O, Kuechlin S, Yakulov TA, Engel C, Müller B, Bensch R, Ronneberger O, Huber TB, Lienkamp SS and Walz G. (2015) The polarity protein Inturned links NPHP4 to Daam1 to control the subapical actin network in multiciliated cells J Cell Biol, doi: 10.1083/jcb.201502043.

M. Gorski, A. Tin, M. Garnaas, G. M. McMahon, A. Y. Chu, B. O. Tayo, C. Pattaro, A. Teumer, D. I. Chasman, J. Chalmers, P. Hamet, J. Tremblay, M. Woodward, T. Aspelund, G. Eiriksdottir, V. Gudnason, T. B. Harris, L. J. Launer, A. V. Smith, B. D. Mitchell, J. R. O'Connell, A. R. Shuldiner, J. Coresh, M. Li, P. Freudenberger, E. Hofer, H. Schmidt, R. Schmidt, E. G. Holliday, P. Mitchell, J. J. Wang, I. H. de Boer, G. Li, D. S. Siscovick, Z. Kutalik, T. Corre, P. Vollenweider, G. Waeber, J. Gupta, P. A. Kanetsky, S. J. Hwang, M. Olden, Q. Yang, M. de Andrade, E. J. Atkinson, S. L. Kardia, S. T. Turner, J. M. Stafford, J. Ding, Y. Liu, C. Barlassina, D. Cusi, E. Salvi, J. A. Staessen, P. M. Ridker, H. Grallert, C. Meisinger, M. Muller-Nurasyid, B. K. Kramer, H. Kramer, S. E. Rosas, I. M. Nolte, B. W. Penninx, H. Snieder, M. Fabiola Del Greco, A. Franke, U. Nothlings, W. Lieb, S. J. Bakker, R. T. Gansevoort, P. van der Harst, A. Dehghan, O. H. Franco, A. Hofman, F. Rivadeneira, S. Sedaghat, A. G. Uitterlinden, S. Coassin, M. Haun, B. Kollerits, F. Kronenberg, B. Paulweber, N. Aumann, K. Endlich, M. Pietzner, U. Volker, R. Rettig, V. Chouraki, C. Helmer, J. C. Lambert, M. Metzger, B. Stengel, T. Lehtimaki, L. P. Lyytikainen, O. Raitakari, A. Johnson, A. Parsa, M. Bochud, I. M. Heid, W. Goessling, A. Kottgen, W. H. Kao, C. S. Fox and C. A. Boger (2014) Genome-wide association study of kidney function decline in individuals of European descent Kidney Int Kidney Int.

S. Zschiedrich, K. Budde and G. Walz (2014) Effect of everolimus on polycystic liver volume in autosomal dominant polycystic kidney disease Clin Exp Nephrol, ahead of print

J. Jing, J. T. Kielstein, U. T. Schultheiss, T. Sitter, S. I. Titze, E. S. Schaeffner, M. McAdams-DeMarco, F. Kronenberg, K. U. Eckardt and A. Kottgen (2014) Prevalence and correlates of gout in a large cohort of patients with chronic kidney disease: the German Chronic Kidney Disease (GCKD) study Clin J Am Soc Nephrol

M. Taschner, F. Kotsis, P. Braeuer, E.W. Kuehn, E. Lorentzen (2014) Crystal structures of IFT70/52 and IFT52/46 provide insight into intraflagellar transport B core complex assembly J Cell Biol 207(2), 269-82.

A. O. Khan, C. Bergmann, T. Eisenberger and H. J. Bolz (2014) A TULP1 founder mutation, p.Gln301*, underlies a recognisable congenital rod-cone dystrophy phenotype on the Arabian Peninsula Br J Ophthalmol, doi: 10.1136/bjophthalmol-2014-305836

G. Ling, D. Landau, C. Bergmann, E. Maor and B. Yerushalmi (2014) Neonatal ascites in autosomal recessive polycystic kidney disease (ARPKD) Clin Nephrol

K. Petzold, R. T. Gansevoort, A. C. Ong, O. Devuyst, L. Rotar, K. U. Eckardt, A. Kottgen, Y. Pirson, G. Remuzzi, R. Sandford, V. Tesar, T. Ecder, D. Chaveau, R. Torra, K. Budde, Y. Le Meur, R. P. Wuthrich and A. L. Serra (2014) Building a network of ADPKD reference centres across Europe: the EuroCYST initiative Nephrol Dial Transplant 29, Suppl 4, iv26-32

P. Huppke, E. Wegener, H. Bohrer-Rabel, H. J. Bolz, B. Zoll, J. Gartner and C. Bergmann (2014) Tectonic gene mutations in patients with Joubert syndrome Eur J Hum Genet, doi: 10.1038/ejhg.2014.160

V. Frank, K. Zerres and C. Bergmann (2014) Transcriptional complexity in autosomal recessive polycystic kidney disease Clin J Am Soc Nephrol 9, 1729-36

L. Borgal, M. M. Rinschen, C. Dafinger, S. Hoff, M. J. Reinert, T. Lamkemeyer, S. S. Lienkamp, T. Benzing and B. Schermer (2014) Casein Kinase 1 alpha Phosphorylates the Wnt Regulator Jade-1 and Modulates Its Activity J Biol Chem 289, 26344-56.

B. B. Beck, J. B. Phillips, M. P. Bartram, J. Wegner, M. Thoenes, A. Pannes, J. Sampson, R. Heller, H. Gobel, F. Koerber, A. Neugebauer, A. Hedergott, G. Nurnberg, P. Nurnberg, H. Thiele, J. Altmuller, M. R. Toliat, S. Staubach, K. M. Boycott, E. M. Valente, A. R. Janecke, T. Eisenberger, C. Bergmann, L. Tebbe, Y. Wang, Y. Wu, A. M. Fry, M. Westerfield, U. Wolfrum and H. J. Bolz (2014) Mutation of POC1B in a severe syndromic retinal ciliopathy Hum Mutat 35, 1153-62

M. Mizunuma, E. Neumann-Haefelin, N. Moroz, Y. Li and T. K. Blackwell (2014) mTORC2-SGK-1 acts in two environmentally responsive pathways with opposing effects on longevity Aging Cell 13, 869-78

A. O. Khan, S. Nagl, C. Bergmann and H. J. Bolz (2014) Limited ocular motility in a child with 3q23 microdeletion ("blepharophimosis syndrome plus") Pediatr Ophthalmol Strabismus 51, e51-4

L. M. Guay-Woodford, J. J. Bissler, M. C. Braun, D. Bockenhauer, M. A. Cadnapaphornchai, K. M. Dell, L. Kerecuk, M. C. Liebau, M. H. Alonso-Peclet, B. Shneider, S. Emre, T. Heller, B. M. Kamath, K. F. Murray, K. Moise, E. E. Eichenwald, J. Evans, R. L. Keller, L. Wilkins-Haug, C. Bergmann, M. Gunay-Aygun, S. R. Hooper, K. K. Hardy, E. A. Hartung, R. Streisand, R. Perrone and M. Moxey-Mims (2014) Consensus Expert Recommendations for the Diagnosis and Management of Autosomal Recessive Polycystic Kidney Disease: Report of an International Conference Journal.

R. B. Scharpf, L. Mireles, Q. Yang, A. Kottgen, I. Ruczinski, K. Susztak, E. Halper-Stromberg, A. Tin, S. Cristiano, A. Chakravarti, E. Boerwinkle, C. S. Fox, J. Coresh and W. H. Linda Kao (2014) Copy number polymorphisms near SLC2A9 are associated with serum uric acid concentrations BMC Genet 15, 81

A. O. Khan, S. Al-Mesfer, S. Al-Turkmani, C. Bergmann and H. J. Bolz (2014) Genetic analysis of strictly defined Leber congenital amaurosis with (and without) neurodevelopmental delay Journal.

F. Grahammer, N. Haenisch, F. Steinhardt, L. Sander, M. Roerden, F. Arnold, T. Cordts, N. Wanner, W. Reichardt, D. Kerjaschki, M. A. Ruegg, M. N. Hall, P. Moulin, H. Busch, M. Boerries, G. Walz, F. Artunc and T. B. Huber (2014) mTORC1 maintains renal tubular homeostasis and is essential in response to ischemic stress Proc Natl Acad Sci USA 111, E2817-26

C. Boehlke, B. Hartleben, T. B. Huber, H. Hopfer, G. Walz and E. Neumann-Haefelin (2014) Hantavirus infection with severe proteinuria and podocyte foot-process effacement Am J Kidney Dis 64, 452-456

E. M. Gleixner, G. Canaud, T. Hermle, M. C. Guida, O. Kretz, M. Helmstadter, T. B. Huber, S. Eimer, F. Terzi and M. Simons (2014) V-ATPase/mTOR signaling regulates megalin-mediated apical endocytosis Cell Rep 8, 10-19

T. Ghosh, J. Aprea, J. Nardelli, H. Engel, C. Selinger, C. Mombereau, T. Lemmonnier, I. Moutkine, L. Schwendimann, M. Dori, T. Irinopoulou, A. Henrion Caude, A.G. Benecke, S.J. Arnold, P. Gressens, F. Calegari, and M. Groszer (2014) MicroRNAs establish robustness and adaptability of a critical gene network to regulate progenitor fate decisions during cortical neurogenesis Cell Reports 7, 1-10

D. Li, E.W. Kuehn, R. Prekeris (2014) Kinesin-2 mediates apical endosome transport during epithelial lumen formation Cell Logist 4(1), e28928. Epub 2014 May 6.

M. Christmann, M. Hansen, C. Bergmann, D. Schwabe, J. Brand and W. Schneider (2014) Eculizumab as first-line therapy for atypical hemolytic uremic syndrome Pediatrics 133, e1759-63

M. M. Altintas, K. Moriwaki, C. Wei, C. C. Moller, J. Flesche, J. Li, S. Yaddanapudi, M. H. Faridi, M. Godel, T. B. Huber, R. A. Preston, J. X. Jiang, D. Kerjaschki, S. Sever and J. Reiser (2014) Reduction of proteinuria through podocyte alkalinization J Biol Chem 289, 17454-67

W. Bechtel-Walz and T. B. Huber (2014) Chromatin dynamics in kidney development and function Cell Tissue Res 356, 601-608

M. Semmo, M. Kottgen and A. Hofherr (2014) The TRPP subfamily and polycystin-1 proteins Handb Exp Pharmacol 222, 675-711

CSN Klose, M. Flach, L. Möhle, L. Rogell, T. Hoyler, K. Ebert, C. Fabiunke, D. Pfeifer, V. Sexl, A. Souabni, D. Fonseca-Pereira, R.G. Domingues, H. Veiga-Fernandes, S.J. Arnold, M. Busslinger, I.R. Dunay, Y. Tanriver, and A. Diefenbach (2014) Differentiation of type 1 ILCs from a common progenitor to all helper-like innate lymphoid cell lineages Cell 157, 240-356

A. Hofherr, C. Wagner, S. Fedeles, S. Somlo and M. Kottgen (2014) N-glycosylation determines the abundance of the transient receptor potential channel TRPP2 J Biol Chem 289, 14854-67

W. R. Cnossen, R. H. te Morsche, A. Hoischen, C. Gilissen, M. Chrispijn, H. Venselaar, S. Mehdi, C. Bergmann, J. A. Veltman and J. P. Drenth (2014) Whole-exome sequencing reveals LRP5 mutations and canonical Wnt signaling associated with hepatic cystogenesis Journal 111, 5343-8.

A. O. Khan, H. J. Bolz and C. Bergmann (2014) Early-onset severe retinal dystrophy as the initial presentation of IFT140-related skeletal ciliopathy Journal 18, 203-5.

A. O. Khan, H. J. Bolz and C. Bergmann (2014) Results of fibrillin-1 gene analysis in children from inbred families with lens subluxation Journal 18, 134-9.

A. B. Ekici, T. Hackenbeck, V. Moriniere, A. Pannes, M. Buettner, S. Uebe, R. Janka, A. Wiesener, I. Hermann, S. Grupp, M. Hornberger, T. B. Huber, N. Isbel, G. Mangos, S. McGinn, D. Soreth-Rieke, B. B. Beck, M. Uder, K. Amann, C. Antignac, A. Reis, K. U. Eckardt and M. S. Wiesener (2014) Renal fibrosis is the common feature of autosomal dominant tubulointerstitial kidney diseases caused by mutations in mucin 1 or uromodulin Kidney Int 86, 589-99

T. Eisenberger, N. Di Donato, S. M. Baig, C. Neuhaus, A. Beyer, E. Decker, D. Murbe, C. Decker, C. Bergmann and H. J. Bolz (2014) Targeted and genomewide NGS data disqualify mutations in MYO1A, the "DFNA48 gene", as a cause of deafness Hum Mutat 35, 565-70

E. Z. Taskiran, E. Korkmaz, S. Gucer, C. Kosukcu, F. Kaymaz, C. Koyunlar, E. C. Bryda, M. Chaki, D. Lu, K. Vadnagara, C. Candan, R. Topaloglu, F. Schaefer, M. Attanasio, C. Bergmann and F. Ozaltin (2014) Mutations in ANKS6 cause a nephronophthisis-like phenotype with ESRD J Am Soc Nephrol 25, 1653-61

M. Sukalo, A. Fiedler, C. Guzman, S. Spranger, M. C. Addor, J. N. McHeik, M. Oltra Benavent, J. M. Cobben, L. A. Gillis, A. G. Shealy, C. Deshpande, B. Bozorgmehr, D. B. Everman, E. L. Stattin, J. Liebelt, K. M. Keller, D. R. Bertola, C. D. van Karnebeek, C. Bergmann, Z. Liu, G. Duker, N. Rezaei, F. S. Alkuraya, G. Ogur, A. Alrajoudi, C. A. Venegas-Vega, N. E. Verbeek, E. J. Richmond, O. Kirbiyik, P. Ranganath, A. Singh, K. Godbole, F. A. Ali, C. Alves, J. Mayerle, M. M. Lerch, H. Witt and M. Zenker (2014) Mutations in the human UBR1 gene and the associated phenotypic spectrum Journal 35, 521-31.

Y. Tanriver and A. Diefenbach (2014) Transcription factors controlling development and function of innate lymphoid cells Int Immunol 26, 119-128

Q. Zhou, J. Neubauer, J. S. Kern, W. Grotz, G. Walz and T. B. Huber (2014) Calciphylaxis Lancet 383, 1067.

H. Fehrenbach, C. Decker, T. Eisenberger, V. Frank, T. Hampel, U. Walden, K. U. Amann, I. Kruger-Stollfuss, H. J. Bolz, K. Haffner, M. Pohl and C. Bergmann (2014) Mutations in WDR19 encoding the intraflagellar transport component IFT144 cause a broad spectrum of ciliopathies Pediatr Nephrol 29, 1451-6

H. Ramachandran, T. Schafer, Y. Kim, K. Herfurth, S. Hoff, S. S. Lienkamp, A. Kramer-Zucker and G. Walz (2014) Interaction with the Bardet-Biedl Gene Product TRIM32/BBS11 Modifies the Half-life and Localization of Glis2/NPHP7 J Biol Chem 289, 8390-401.

F. Grahammer, N. Wanner and T. B. Huber (2014) mTOR controls kidney epithelia in health and disease Nephrol Dial Transplant 29, Suppl 1, i9-i18

B. Hartleben, N. Wanner and T. B. Huber (2014) Autophagy in glomerular health and disease Semin Nephrol 34, 42-52

D. Zhu, S. Holz, E. Metzger, M. Pavlovic, A. Jandausch, C. Jilg, P. Galgoczy, C. Herz, M. Moser, D. Metzger, T. Gunther, S. J. Arnold and R. Schule (2014) Lysine-specific demethylase 1 regulates differentiation onset and migration of trophoblast stem cells Nat Commun 5, 3174.

N. Wanner, B. Hartleben, N. Herbach, M. Goedel, N. Stickel, R. Zeiser, G. Walz, M. J. Moeller, F. Grahammer and T. B. Huber (2014) Unraveling the Role of Podocyte Turnover in Glomerular Aging and Injury J Am Soc Nephrol., 4, 707-716

B. Hartleben, E. Widmeier, N. Wanner, M. Schmidts, S. T. Kim, L. Schneider, B. Mayer, D. Kerjaschki, J. H. Miner, G. Walz and T. B. Huber (2014) Correction: Role of the Polarity Protein Scribble for Podocyte Differentiation and Maintenance PLoS One 9.

T. Schmidt, T. Bierhals, F. Kortum, I. Bartels, T. Liehr, P. Burfeind, M. Shoukier, V. Frank, C. Bergmann and K. Kutsche (2014) Branchio-otic syndrome caused by a genomic rearrangement: clinical findings and molecular cytogenetic studies in a patient with a pericentric inversion of chromosome 8 Cytogenet Genome Res 142, 1-6.

J. Guzman, A. N. Jauregui, S. Merscher-Gomez, D. Maiguel, C. Muresan, A. Mitrofanova, A. Diez-Sampedro, J. Szust, T. H. Yoo, R. Villarreal, C. Pedigo, R. D. Molano, K. Johnson, B. Kahn, B. Hartleben, T. B. Huber, J. Saha, G. W. Burke, 3rd, E. D. Abel, F. C. Brosius and A. Fornoni (2014) Podocyte-Specific GLUT4-Deficient Mice Have Fewer and Larger Podocytes and Are Protected From Diabetic Nephropathy Diabetes 63, 701-14.

N.A. Vasistha, F. Garcia-Moreno, S. Arora, A. Cheung, S.J. Arnold, E.J. Robertson, and Z. Molnár (2014) Cortical and clonal contribution of Tbr2 expressing progenitors in the developing mouse brain Cerebral Cortex, doi:10.1093/cercor/bhu125

CSN Klose, K. Blatz, M. Kofoed-Nielsen, Y. d?Hargues, K. Ebert, S.J. Arnold, E. Palmer, A. Diefenbach, and Y. Tanriver (2014) The Transcription Factor T-bet Is Induced by IL-15 and Thymic Agonist Selection and Controls CD8 alpha alpha(+) Intraepithelial Lymphocyte DevelopmentInduction of T-bet Immunity 41, 230-243

M. Tholen, L.E. Hillebrand, S. Tholen, O. Sedelmeier, S.J. Arnold, and T.Reinheckel (2014) Out-of-frame start codons prevent translation of truncated nucleo-cytosolic cathepsin L in vivo Nat Commun 5, 4931, doi:10.1038/ncomms5931

C. E. Weidgang, R. Russell, P. R. Tata, S. J. Kuhl, A. Illing, M. Muller, Q. Lin, C. Brunner, T. M. Boeckers, K. Bauer, A. E. Kartikasari, Y. Guo, M. Radenz, C. Bernemann, M. Weiss, T. Seufferlein, M. Zenke, M. Iacovino, M. Kyba, H. R. Scholer, M. Kuhl, S. Liebau and A. Kleger (2013) TBX3 Directs Cell-Fate Decision toward Mesendoderm Stem Cell Reports 1, 248-65.

T. Eisenberger, C. Neuhaus, A. O. Khan, C. Decker, M. N. Preising, C. Friedburg, A. Bieg, M. Gliem, P. Charbel Issa, F. G. Holz, S. M. Baig, Y. Hellenbroich, A. Galvez, K. Platzer, B. Wollnik, N. Laddach, S. R. Ghaffari, M. Rafati, E. Botzenhart, S. Tinschert, D. Borger, A. Bohring, J. Schreml, S. Kortge-Jung, C. Schell-Apacik, K. Bakur, J. Y. Al-Aama, T. Neuhann, P. Herkenrath, G. Nurnberg, P. Nurnberg, J. S. Davis, A. Gal, C. Bergmann, B. Lorenz and H. J. Bolz (2013) Increasing the yield in targeted next-generation sequencing by implicating CNV analysis, non-coding exons and the overall variant load: the example of retinal dystrophies PLoS One 8, e78496.

N. Figueiredo, A. Chora, H. Raquel, N. Pejanovic, P. Pereira, B. Hartleben, A. Neves-Costa, C. Moita, D. Pedroso, A. Pinto, S. Marques, H. Faridi, P. Costa, R. Gozzelino, J. L. Zhao, M. P. Soares, M. Gama-Carvalho, J. Martinez, Q. Zhang, G. Doring, M. Grompe, J. P. Simas, T. B. Huber, D. Baltimore, V. Gupta, D. R. Green, J. A. Ferreira and L. F. Moita (2013) Anthracyclines induce DNA damage response-mediated protection against severe sepsis Immunity 39, 874-84.

R. Weiskirchen, J. Weimer, S. K. Meurer, A. Kron, B. Seipel, I. Vater, N. Arnold, R. Siebert, L. Xu, S. L. Friedman and C. Bergmann (2013) Genetic characteristics of the human hepatic stellate cell line LX-2 PLoS One 8, e75692.

K. Worthmann, M. Leitges, B. Teng, M. Sestu, I. Tossidou, T. Samson, H. Haller, T. B. Huber and M. Schiffer (2013) Def-6, a novel regulator of small GTPases in podocytes, acts downstream of atypical protein kinase C (aPKC) lambda/iota Am J Pathol 183, 1945-59.

Y. H. Kim, D. Epting, K. Slanchev, C. Engel, G. Walz and A. Kramer-Zucker (2013) A complex of BBS1 and NPHP7 is required for cilia motility in zebrafish PLoS One 8, e72549.

C. M. O'Seaghdha, H. Wu, Q. Yang, K. Kapur, I. Guessous, A. M. Zuber, A. Kottgen, C. Stoudmann, A. Teumer, Z. Kutalik, M. Mangino, A. Dehghan, W. Zhang, G. Eiriksdottir, G. Li, T. Tanaka, L. Portas, L. M. Lopez, C. Hayward, K. Lohman, K. Matsuda, S. Padmanabhan, D. Firsov, R. Sorice, S. Ulivi, A. C. Brockhaus, M. E. Kleber, A. Mahajan, F. D. Ernst, V. Gudnason, L. J. Launer, A. Mace, E. Boerwinckle, D. E. Arking, C. Tanikawa, Y. Nakamura, M. J. Brown, J. M. Gaspoz, J. M. Theler, D. S. Siscovick, B. M. Psaty, S. Bergmann, P. Vollenweider, V. Vitart, A. F. Wright, T. Zemunik, M. Boban, I. Kolcic, P. Navarro, E. M. Brown, K. Estrada, J. Ding, T. B. Harris, S. Bandinelli, D. Hernandez, A. B. Singleton, G. Girotto, D. Ruggiero, A. P. d'Adamo, A. Robino, T. Meitinger, C. Meisinger, G. Davies, J. M. Starr, J. C. Chambers, B. O. Boehm, B. R. Winkelmann, J. Huang, F. Murgia, S. H. Wild, H. Campbell, A. P. Morris, O. H. Franco, A. Hofman, A. G. Uitterlinden, F. Rivadeneira, U. Volker, A. Hannemann, R. Biffar, W. Hoffmann, S. Y. Shin, P. Lescuyer, H. Henry, C. Schurmann, S. Consortium, G. Consortium, P. B. Munroe, P. Gasparini, N. Pirastu, M. Ciullo, C. Gieger, W. Marz, L. Lind, T. D. Spector, A. V. Smith, I. Rudan, J. F. Wilson, O. Polasek, I. J. Deary, M. Pirastu, L. Ferrucci, Y. Liu, B. Kestenbaum, J. S. Kooner, J. C. Witteman, M. Nauck, W. H. Kao, H. Wallaschofski, O. Bonny, C. S. Fox and M. Bochud (2013) Meta-analysis of genome-wide association studies identifies six new Loci for serum calcium concentrations PLoS Genet 9, e1003796.

C. Boehlke, F. Kotsis, B. Buchholz, C. Powelske, K. U. Eckardt, G. Walz, R. Nitschke and E. W. Kuehn (2013) Correction: Kif3a Guides Microtubular Dynamics, Migration and Lumen Formation of MDCK Cells PLoS One 8.

G. Canaud, F. Bienaime, A. Viau, C. Treins, W. Baron, C. Nguyen, M. Burtin, S. Berissi, K. Giannakakis, A. O. Muda, S. Zschiedrich, T. B. Huber, G. Friedlander, C. Legendre, M. Pontoglio, M. Pende and F. Terzi (2013) AKT2 is essential to maintain podocyte viability and function during chronic kidney disease Nat Med 19, 1288-96.

A. Galvez-Ruiz, C. Neuhaus, C. Bergmann and H. Bolz (2013) First cases of dominant optic atrophy in Saudi Arabia: report of two novel OPA1 mutations J Neuroophthalmol 33, 349-53.

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M. Mergen, C. Engel, B. Muller, M. Follo, T. Schafer, M. Jung and G. Walz (2013) The nephronophthisis gene product NPHP2/Inversin interacts with Aurora A and interferes with HDAC6-mediated cilia disassembly Nephrol Dial Transplant 28, 2744-53.

A. Hofherr and M. Kottgen (2013) Induced pluripotent stem cells from polycystic kidney disease patients: a novel tool to model the pathogenesis of cystic kidney disease J Am Soc Nephrol 24, 1507-9

F. Grahammer, C. Schell and T. B. Huber (2013) The podocyte slit diaphragm--from a thin grey line to a complex signalling hub Nat Rev Nephrol 9, 587-98.

V. Ruf, C. Holzem, T. Peyman, G. Walz, T. K. Blackwell and E. Neumann-Haefelin (2013) TORC2 signaling antagonizes SKN-1 to induce C. elegans mesendodermal embryonic development Dev Biol 384, 214-27.

K. Thedieck, B. Holzwarth, M. T. Prentzell, C. Boehlke, K. Klasener, S. Ruf, A. G. Sonntag, L. Maerz, S. N. Grellscheid, E. Kremmer, R. Nitschke, E. W. Kuehn, J. W. Jonker, A. K. Groen, M. Reth, M. N. Hall and R. Baumeister (2013) Inhibition of mTORC1 by astrin and stress granules prevents apoptosis in cancer cells Cell 154, 859-74.

A. Peired, M. L. Angelotti, E. Ronconi, G. la Marca, B. Mazzinghi, A. Sisti, D. Lombardi, E. Giocaliere, M. Della Bona, F. Villanelli, E. Parente, L. Ballerini, C. Sagrinati, N. Wanner, T. B. Huber, H. Liapis, E. Lazzeri, L. Lasagni and P. Romagnani (2013) Proteinuria impairs podocyte regeneration by sequestering retinoic acid J Am Soc Nephrol 24, 1756-68.

L. Rampoldi, A. Kottgen and O. Devuyst (2013) The effect of common uromodulin variants on urinary protein level and gene transcription Kidney Int 84, 410-1.

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C. Roth, J. Kleffmann, C. Bergmann, W. Deinsberger and A. Ferbert (2013) Ruptured Cerebral Aneurysm and Acute Bilateral Carotid Artery Dissection in a Patient with Polycystic Kidney Disease and Polycystic Liver Disease Cerebrovasc Dis 35, 590-591.

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M. Godel and T. B. Huber (2013) Immunosuppression for membranous nephropathy Lancet 381, 2161.

O. N. Goek, C. Prehn, P. Sekula, W. Romisch-Margl, A. Doring, C. Gieger, M. Heier, W. Koenig, R. Wang-Sattler, T. Illig, K. Suhre, J. Adamski, A. Kottgen and C. Meisinger (2013) Metabolites associate with kidney function decline and incident chronic kidney disease in the general population Nephrol Dial Transplant 28, 2131-8.

F. Grahammer, N. Wanner and T. B. Huber (2013) Podocyte regeneration: who can become a podocyte? Am J Pathol 183, 333-5.

K. U. Eckardt, J. Coresh, O. Devuyst, R. J. Johnson, A. Kottgen, A. S. Levey and A. Levin (2013) Evolving importance of kidney disease: from subspecialty to global health burden Lancet 382, 158-69.

C. Boehlke, F. Kotsis, B. Buchholz, C. Powelske, K. U. Eckardt, G. Walz, R. Nitschke and E. W. Kuehn (2013) Kif3a guides microtubular dynamics, migration and lumen formation of MDCK cells PLoS One 8, e62165.

L. Speksnijder, T. E. Cohen-Overbeek, M. F. Knapen, S. M. Lunshof, A. J. Hoogeboom, A. M. van den Ouwenland, I. F. de Coo, M. H. Lequin, H. J. Bolz, C. Bergmann, L. G. Biesecker, P. J. Willems and M. W. Wessels (2013) A de novo GLI3 mutation in a patient with acrocallosal syndrome Am J Med Genet A 161, 1394-400.

W. Bechtel, M. Helmstadter, J. Balica, B. Hartleben, C. Schell and T. B. Huber (2013) The class III phosphatidylinositol 3-kinase PIK3C3/VPS34 regulates endocytosis and autophagosome-autolysosome formation in podocytes Autophagy 9, 1097-9.

F. Brinkert, A. Lehnhardt, C. Montoya, K. Helmke, H. Schaefer, L. Fischer, B. Nashan, C. Bergmann, R. Ganschow and M. J. Kemper (2013) Combined liver-kidney transplantation for children with autosomal recessive polycystic kidney disease (ARPKD): indication and outcome Transpl Int 26, 640-50.

L. Zhang, K. L. Spencer, V. S. Voruganti, N. W. Jorgensen, M. Fornage, L. G. Best, K. D. Brown-Gentry, S. A. Cole, D. C. Crawford, E. Deelman, N. Franceschini, A. L. Gaffo, K. R. Glenn, G. Heiss, N. S. Jenny, A. Kottgen, Q. Li, K. Liu, T. C. Matise, K. E. North, J. G. Umans and W. H. Kao (2013) Association of Functional Polymorphism rs2231142 (Q141K) in the ABCG2 Gene With Serum Uric Acid and Gout in 4 US Populations: The PAGE Study Am J Epidemiol.

L. A. Smyth, K. Ratnasothy, A. Moreau, S. Alcock, P. Sagoo, L. Meader, Y. Tanriver, M. Buckland, R. Lechler and G. Lombardi (2013) Tolerogenic Donor-Derived Dendritic Cells Risk Sensitization In Vivo owing to Processing and Presentation by Recipient APCs Immunol 190, 4848-60

A. Tin, E. Colantuoni, E. Boerwinkle, A. Kottgen, N. Franceschini, B. C. Astor, J. Coresh and W. H. Kao (2013) Using multiple measures for quantitative trait association analyses: application to estimated glomerular filtration rate J Hum Genet 58, 461-6.

C. Bergmann (2013) Autosomal-recessive polycystic kidney disease gets more complex Gastroenterology 144, 1155-6.

O. M. Woodward, D. N. Tukaye, J. Cui, P. Greenwell, L. M. Constantoulakis, B. S. Parker, A. Rao, M. Kottgen, P. C. Maloney and W. B. Guggino (2013) Gout-causing Q141K mutation in ABCG2 leads to instability of the nucleotide-binding domain and can be corrected with small molecules Proc Natl Acad Sci U S A 110, 5223-8

W. Bechtel, M. Helmstadter, J. Balica, B. Hartleben, B. Kiefer, F. Hrnjic, C. Schell, O. Kretz, S. Liu, F. Geist, D. Kerjaschki, G. Walz and T. B. Huber (2013) Vps34 deficiency reveals the importance of endocytosis for podocyte homeostasis J Am Soc Nephrol 24, 727-43.

F. Modde, P. A. Agustian, J. Wittig, M. E. Dammrich, V. Forstmeier, U. Vester, T. Ahlenstiel, K. Froede, U. Budde, A. M. Wingen, A. Schwarz, S. Lovric, J. T. Kielstein, C. Bergmann, N. Bachmann, M. Nagel, H. H. Kreipe, V. Brocker, C. L. Bockmeyer and J. U. Becker (2013) Comprehensive analysis of glomerular mRNA expression of pro- and antithrombotic genes in atypical haemolytic-uremic syndrome (aHUS) Virchows Arch 462, 455-64.

M. Olden, A. Teumer, M. Bochud, C. Pattaro, A. Kottgen, S. T. Turner, R. Rettig, M. H. Chen, A. Dehghan, F. Bastardot, R. Schmidt, P. Vollenweider, H. Schunkert, M. P. Reilly, M. Fornage, L. J. Launer, G. C. Verwoert, G. F. Mitchell, J. C. Bis, C. J. O'Donnell, C. Y. Cheng, X. Sim, D. S. Siscovick, J. Coresh, W. H. Kao, C. S. Fox, C. M. O'Seaghdha, C. C. E. C. I. M. T. I. N. AortaGen and C. K. Consortia (2013) Overlap between common genetic polymorphisms underpinning kidney traits and cardiovascular disease phenotypes: the CKDGen consortium Am J Kidney Dis 61, 889-98.

C. Schell, L. Baumhakl, S. Salou, A. C. Conzelmann, C. Meyer, M. Helmstadter, C. Wrede, F. Grahammer, S. Eimer, D. Kerjaschki, G. Walz, S. Snapper and T. B. Huber (2013) N-wasp is required for stabilization of podocyte foot processes J Am Soc Nephrol 24, 713-21.

Y. Li and A. Kottgen (2013) Genetic investigations of kidney disease: core curriculum 2013 Am J Kidney Dis 61, 832-44.

M. Godel, B. N. Ostendorf, J. Baumer, K. Weber and T. B. Huber (2013) A novel domain regulating degradation of the glomerular slit diaphragm protein podocin in cell culture systems PLoS One 8, e57078.

V. Frank, S. Habbig, M. P. Bartram, T. Eisenberger, H. E. Veenstra-Knol, C. Decker, R. A. Boorsma, H. Gobel, G. Nurnberg, A. Griessmann, M. Franke, L. Borgal, P. Kohli, L. A. Volker, J. Dotsch, P. Nurnberg, T. Benzing, H. J. Bolz, C. Johnson, E. H. Gerkes, B. Schermer and C. Bergmann (2013) Mutations in NEK8 link multiple organ dysplasia with altered Hippo signalling and increased c-MYC expression Hum Mol Genet 22, 2177-85.

M. Schmidts, V. Frank, T. Eisenberger, S. Al Turki, A. A. Bizet, D. Antony, S. Rix, C. Decker, N. Bachmann, M. Bald, T. Vinke, B. Toenshoff, N. Di Donato, T. Neuhann, J. L. Hartley, E. R. Maher, R. Bogdanovic, A. Peco-Antic, C. Mache, M. E. Hurles, I. Joksic, M. Guc-Scekic, J. Dobricic, M. Brankovic-Magic, H. J. Bolz, G. J. Pazour, P. L. Beales, P. J. Scambler, S. Saunier, H. M. Mitchison and C. Bergmann (2013) Combined NGS approaches identify mutations in the intraflagellar transport gene IFT140 in skeletal ciliopathies with early progressive kidney Disease Hum Mutat 34, 714-24.

M. Boerries, F. Grahammer, S. Eiselein, M. Buck, C. Meyer, M. Goedel, W. Bechtel, S. Zschiedrich, D. Pfeifer, D. Laloe, C. Arrondel, S. Goncalves, M. Kruger, S. J. Harvey, H. Busch, J. Dengjel and T. B. Huber (2013) Molecular fingerprinting of the podocyte reveals novel gene and protein regulatory networks Kidney Int 83, 1052-64.

E. W. Kuhn (2013) [Diagnosis, course and treatment of autosomal dominant polycystic kidney disease] Dtsch Med Wochenschr 138, 196-8.

S. P. Juraschek, J. Coresh, L. A. Inker, A. S. Levey, A. Kottgen, M. C. Foster, B. C. Astor, J. H. Eckfeldt and E. Selvin (2013) Comparison of serum concentrations of beta-trace protein, beta2-microglobulin, cystatin C, and creatinine in the US population Clin J Am Soc Nephrol 8, 584-92.

B. Hartleben, E. Widmeier, M. Suhm, K. Worthmann, C. Schell, M. Helmstadter, T. Wiech, G. Walz, M. Leitges, M. Schiffer and T. B. Huber (2013) aPKClambda/iota and aPKCzeta contribute to podocyte differentiation and glomerular maturation J Am Soc Nephrol 24, 253-67.

F. Kotsis, C. Boehlke and E. W. Kuehn (2013) The ciliary flow sensor and polycystic kidney disease Nephrol Dial Transplant 28, 518-26.

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R. Schild, T. Knuppel, M. Konrad, C. Bergmann, A. Trautmann, M. J. Kemper, K. Wu, S. Yaklichkin, J. Wang, R. Pestell, D. E. Muller-Wiefel, F. Schaefer and S. Weber (2013) Double homozygous missense mutations in DACH1 and BMP4 in a patient with bilateral cystic renal dysplasia Nephrol Dial Transplant 28, 227-32.

F. Grahammer, C. Schell and T. B. Huber (2013) Molecular understanding of the slit diaphragm Pediatr Nephrol 28, 1957-62.

A. Schober, R. Parlato, K. Huber, R. Kinscherf, B. Hartleben, T. B. Huber, G. Schutz and K. Unsicker (2013) Cell loss and autophagy in the extra-adrenal chromaffin organ of Zuckerkandl are regulated by glucocorticoid signalling J Neuroendocrinol 25, 34-47.

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H. Vastinsalo, R. Jalkanen, C. Bergmann, C. Neuhaus, L. Kleemola, L. Jauhola, H. J. Bolz and E. M. Sankila (2013) Extended mutation spectrum of Usher syndrome in Finland Acta Ophthalmol 91, 325-34.

I. Vogl, S. Eck, A. B. Pages, P. A. Greif, K. Hirv, S. Kotschote, M. Kuhn, A. Gehring, C. Bergmann, H. J. Bolz, M. Stuhrmann, S. Biskup, K. Metzeler and H. G. Klein (2013) Diagnostic applications of next generation sequencing - working towards quality standards J Lab Med (in press).

K. Strasser, J. Hoefele, C. Bergmann, A. K. Buscher, R. Buscher, P. F. Hoyer and S. Weber (2012) COL4A5-associated X-linked Alport syndrome in a female patient with early inner ear deafness due to a mutation in MYH9 Nephrol Dial Transplant 27, 4236-40.

S. S. Lienkamp, K. Liu, C. M. Karner, T. J. Carroll, O. Ronneberger, J. B. Wallingford and G. Walz (2012) Vertebrate kidney tubules elongate using a planar cell polarity-dependent, rosette-based mechanism of convergent extension Nat Genet 44, 1382-7.

C. B. Schell, D. Kerjaschki, J. Reiser and T. B. Huber (2012) Is podocyte research at a tipping point? Report from the 9(th) International Podocyte Conference Kidney Int 82, 1041-3.

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D. I. Chasman, C. Fuchsberger, C. Pattaro, A. Teumer, C. A. Boger, K. Endlich, M. Olden, M. H. Chen, A. Tin, D. Taliun, M. Li, X. Gao, M. Gorski, Q. Yang, C. Hundertmark, M. C. Foster, C. M. O'Seaghdha, N. Glazer, A. Isaacs, C. T. Liu, A. V. Smith, J. R. O'Connell, M. Struchalin, T. Tanaka, G. Li, A. D. Johnson, H. J. Gierman, M. F. Feitosa, S. J. Hwang, E. J. Atkinson, K. Lohman, M. C. Cornelis, A. Johansson, A. Tonjes, A. Dehghan, J. C. Lambert, E. G. Holliday, R. Sorice, Z. Kutalik, T. Lehtimaki, T. Esko, H. Deshmukh, S. Ulivi, A. Y. Chu, F. Murgia, S. Trompet, M. Imboden, S. Coassin, G. Pistis, C. A. Consortium, I. Consortium, C. A. Consortium, Wtccc, T. B. Harris, L. J. Launer, T. Aspelund, G. Eiriksdottir, B. D. Mitchell, E. Boerwinkle, H. Schmidt, M. Cavalieri, M. Rao, F. Hu, A. Demirkan, B. A. Oostra, M. de Andrade, S. T. Turner, J. Ding, J. S. Andrews, B. I. Freedman, F. Giulianini, W. Koenig, T. Illig, C. Meisinger, C. Gieger, L. Zgaga, T. Zemunik, M. Boban, C. Minelli, H. E. Wheeler, W. Igl, G. Zaboli, S. H. Wild, A. F. Wright, H. Campbell, D. Ellinghaus, U. Nothlings, G. Jacobs, R. Biffar, F. Ernst, G. Homuth, H. K. Kroemer, M. Nauck, S. Stracke, U. Volker, H. Volzke, P. Kovacs, M. Stumvoll, R. Magi, A. Hofman, A. G. Uitterlinden, F. Rivadeneira, Y. S. Aulchenko, O. Polasek, N. Hastie, V. Vitart, C. Helmer, J. J. Wang, B. Stengel, D. Ruggiero, S. Bergmann, M. Kahonen, J. Viikari, T. Nikopensius, M. Province, S. Ketkar, H. Colhoun, A. Doney, A. Robino, B. K. Kramer, L. Portas, I. Ford, B. M. Buckley, M. Adam, G. A. Thun, B. Paulweber, M. Haun, C. Sala, P. Mitchell, M. Ciullo, S. K. Kim, P. Vollenweider, O. Raitakari, A. Metspalu, C. Palmer, P. Gasparini, M. Pirastu, J. W. Jukema, N. M. Probst-Hensch, F. Kronenberg, D. Toniolo, V. Gudnason, A. R. Shuldiner, J. Coresh, R. Schmidt, L. Ferrucci, D. S. Siscovick, C. M. van Duijn, I. B. Borecki, S. L. Kardia, Y. Liu, G. C. Curhan, I. Rudan, U. Gyllensten, J. F. Wilson, A. Franke, P. P. Pramstaller, R. Rettig, I. Prokopenko, J. Witteman, C. Hayward, P. M. Ridker, A. Parsa, M. Bochud, I. M. Heid, W. H. Kao, C. S. Fox and A. Kottgen (2012) Integration of genome-wide association studies with biological knowledge identifies six novel genes related to kidney function Hum Mol Genet 21, 5329-43.

P. L. Tharaux and T. B. Huber (2012) How many ways can a podocyte die? Semin Nephrol 32, 394-404.

T. Eisenberger, R. Slim, A. Mansour, M. Nauck, G. Nurnberg, P. Nurnberg, C. Decker, C. Dafinger, I. Ebermann, C. Bergmann and H. J. Bolz (2012) Targeted next-generation sequencing identifies a homozygous nonsense mutation in ABHD12, the gene underlying PHARC, in a family clinically diagnosed with Usher syndrome type 3 Orphanet J Rare Dis 7, 59.

W. Qi, X. Huang, E. Neumann-Haefelin, E. Schulze and R. Baumeister (2012) Cell-nonautonomous signaling of FOXO/DAF-16 to the stem cells of Caenorhabditis elegans PLoS Genet 8, e1002836.

M. Chaki, R. Airik, A. K. Ghosh, R. H. Giles, R. Chen, G. G. Slaats, H. Wang, T. W. Hurd, W. Zhou, A. Cluckey, H. Y. Gee, G. Ramaswami, C. J. Hong, B. A. Hamilton, I. Cervenka, R. S. Ganji, V. Bryja, H. H. Arts, J. van Reeuwijk, M. M. Oud, S. J. Letteboer, R. Roepman, H. Husson, O. Ibraghimov-Beskrovnaya, T. Yasunaga, G. Walz, L. Eley, J. A. Sayer, B. Schermer, M. C. Liebau, T. Benzing, S. Le Corre, I. Drummond, S. Janssen, S. J. Allen, S. Natarajan, J. F. O'Toole, M. Attanasio, S. Saunier, C. Antignac, R. K. Koenekoop, H. Ren, I. Lopez, A. Nayir, C. Stoetzel, H. Dollfus, R. Massoudi, J. G. Gleeson, S. P. Andreoli, D. G. Doherty, A. Lindstrad, C. Golzio, N. Katsanis, L. Pape, E. B. Abboud, A. A. Al-Rajhi, R. A. Lewis, H. Omran, E. Y. Lee, S. Wang, J. M. Sekiguchi, R. Saunders, C. A. Johnson, E. Garner, K. Vanselow, J. S. Andersen, J. Shlomai, G. Nurnberg, P. Nurnberg, S. Levy, A. Smogorzewska, E. A. Otto and F. Hildebrandt (2012) Exome capture reveals ZNF423 and CEP164 mutations, linking renal ciliopathies to DNA damage response signaling Cell 150, 533-48.

M. Helmstadter, K. Luthy, M. Godel, M. Simons, Ashish, D. Nihalani, S. A. Rensing, K. F. Fischbach and T. B. Huber (2012) Functional study of mammalian Neph proteins in Drosophila melanogaster PLoS One 7, e40300.

W. Zhou, E. A. Otto, A. Cluckey, R. Airik, T. W. Hurd, M. Chaki, K. Diaz, F. P. Lach, G. R. Bennett, H. Y. Gee, A. K. Ghosh, S. Natarajan, S. Thongthip, U. Veturi, S. J. Allen, S. Janssen, G. Ramaswami, J. Dixon, F. Burkhalter, M. Spoendlin, H. Moch, M. J. Mihatsch, J. Verine, R. Reade, H. Soliman, M. Godin, D. Kiss, G. Monga, G. Mazzucco, K. Amann, F. Artunc, R. C. Newland, T. Wiech, S. Zschiedrich, T. B. Huber, A. Friedl, G. G. Slaats, J. A. Joles, R. Goldschmeding, J. Washburn, R. H. Giles, S. Levy, A. Smogorzewska and F. Hildebrandt (2012) FAN1 mutations cause karyomegalic interstitial nephritis, linking chronic kidney failure to defective DNA damage repair Nat Genet 44, 910-5.

C. Schell and T. B. Huber (2012) New players in the pathogenesis of focal segmental glomerulosclerosis Nephrol Dial Transplant 27, 3406-12.

J. Busch, V. Frank, N. Bachmann, A. Otsuka, V. Oji, D. Metze, K. Shah, S. Danda, B. Watzer, H. Traupe, H. J. Bolz, K. Kabashima and C. Bergmann (2012) Mutations in the prostaglandin transporter SLCO2A1 cause primary hypertrophic osteoarthropathy with digital clubbing J Invest Dermatol 132, 2473-6.

A. Kottgen, Q. Yang, L. C. Shimmin, A. Tin, C. Schaeffer, J. Coresh, X. Liu, L. Rampoldi, S. J. Hwang, E. Boerwinkle, J. E. Hixson, W. H. Kao and C. S. Fox (2012) Association of estimated glomerular filtration rate and urinary uromodulin concentrations with rare variants identified by UMOD gene region sequencing PLoS One 7, e38311.

J. R. Perry, B. F. Voight, L. Yengo, N. Amin, J. Dupuis, M. Ganser, H. Grallert, P. Navarro, M. Li, L. Qi, V. Steinthorsdottir, R. A. Scott, P. Almgren, D. E. Arking, Y. Aulchenko, B. Balkau, R. Benediktsson, R. N. Bergman, E. Boerwinkle, L. Bonnycastle, N. P. Burtt, H. Campbell, G. Charpentier, F. S. Collins, C. Gieger, T. Green, S. Hadjadj, A. T. Hattersley, C. Herder, A. Hofman, A. D. Johnson, A. Kottgen, P. Kraft, Y. Labrune, C. Langenberg, A. K. Manning, K. L. Mohlke, A. P. Morris, B. Oostra, J. Pankow, A. K. Petersen, P. P. Pramstaller, I. Prokopenko, W. Rathmann, W. Rayner, M. Roden, I. Rudan, D. Rybin, L. J. Scott, G. Sigurdsson, R. Sladek, G. Thorleifsson, U. Thorsteinsdottir, J. Tuomilehto, A. G. Uitterlinden, S. Vivequin, M. N. Weedon, A. F. Wright, Magic, D. Consortium, G. Consortium, F. B. Hu, T. Illig, L. Kao, J. B. Meigs, J. F. Wilson, K. Stefansson, C. van Duijn, D. Altschuler, A. D. Morris, M. Boehnke, M. I. McCarthy, P. Froguel, C. N. Palmer, N. J. Wareham, L. Groop, T. M. Frayling and S. Cauchi (2012) Stratifying type 2 diabetes cases by BMI identifies genetic risk variants in LAMA1 and enrichment for risk variants in lean compared to obese cases PLoS Genet 8, e1002741.

T. B. Huber, C. L. Edelstein, B. Hartleben, K. Inoki, Z. Dong, D. Koya, S. Kume, W. Lieberthal, N. Pallet, A. Quiroga, K. Ravichandran, K. Susztak, S. Yoshida and Z. Dong (2012) Emerging role of autophagy in kidney function, diseases and aging Autophagy 8, 1009-31.

S. Liu, B. Hartleben, O. Kretz, T. Wiech, P. Igarashi, N. Mizushima, G. Walz and T. B. Huber (2012) Autophagy plays a critical role in kidney tubule maintenance, aging and ischemia-reperfusion injury Autophagy 8, 826-37.

B. Hartleben, E. Widmeier, N. Wanner, M. Schmidts, S. T. Kim, L. Schneider, B. Mayer, D. Kerjaschki, J. H. Miner, G. Walz and T. B. Huber (2012) Role of the polarity protein Scribble for podocyte differentiation and maintenance PLoS One 7, e36705.

J. R. Panizzi, A. Becker-Heck, V. H. Castleman, D. A. Al-Mutairi, Y. Liu, N. T. Loges, N. Pathak, C. Austin-Tse, E. Sheridan, M. Schmidts, H. Olbrich, C. Werner, K. Haffner, N. Hellman, R. Chodhari, A. Gupta, A. Kramer-Zucker, F. Olale, R. D. Burdine, A. F. Schier, C. O'Callaghan, E. M. Chung, R. Reinhardt, H. M. Mitchison, S. M. King, H. Omran and I. A. Drummond (2012) CCDC103 mutations cause primary ciliary dyskinesia by disrupting assembly of ciliary dynein arms Nat Genet 44, 714-9.

J. W. Maynard, M. A. McAdams DeMarco, A. N. Baer, A. Kottgen, A. R. Folsom, J. Coresh and A. C. Gelber (2012) Incident gout in women and association with obesity in the Atherosclerosis Risk in Communities (ARIC) Study Am J Med 125, 717 e9-717 e17.

S. Robida-Stubbs, K. Glover-Cutter, D. W. Lamming, M. Mizunuma, S. D. Narasimhan, E. Neumann-Haefelin, D. M. Sabatini and T. K. Blackwell (2012) TOR signaling and rapamycin influence longevity by regulating SKN-1/Nrf and DAF-16/FoxO Cell Metab 15, 713-24.

K. Skouloudaki and G. Walz (2012) YAP1 recruits c-Abl to protect angiomotin-like 1 from Nedd4-mediated degradation PLoS One 7, e35735.

N. A. Bhavsar, A. Kottgen, J. Coresh and B. C. Astor (2012) Neutrophil gelatinase-associated lipocalin (NGAL) and kidney injury molecule 1 (KIM-1) as predictors of incident CKD stage 3: the Atherosclerosis Risk in Communities (ARIC) Study Am J Kidney Dis 60, 233-40.

J. W. Ellis, M. H. Chen, M. C. Foster, C. T. Liu, M. G. Larson, I. de Boer, A. Kottgen, A. Parsa, M. Bochud, C. A. Boger, L. Kao, C. S. Fox, C. M. O'Seaghdha, C. K. Consortium and C. A. R. Consortium (2012) Validated SNPs for eGFR and their associations with albuminuria Hum Mol Genet 21, 3293-8.

C. Pattaro, A. Kottgen, A. Teumer, M. Garnaas, C. A. Boger, C. Fuchsberger, M. Olden, M. H. Chen, A. Tin, D. Taliun, M. Li, X. Gao, M. Gorski, Q. Yang, C. Hundertmark, M. C. Foster, C. M. O'Seaghdha, N. Glazer, A. Isaacs, C. T. Liu, A. V. Smith, J. R. O'Connell, M. Struchalin, T. Tanaka, G. Li, A. D. Johnson, H. J. Gierman, M. Feitosa, S. J. Hwang, E. J. Atkinson, K. Lohman, M. C. Cornelis, A. Johansson, A. Tonjes, A. Dehghan, V. Chouraki, E. G. Holliday, R. Sorice, Z. Kutalik, T. Lehtimaki, T. Esko, H. Deshmukh, S. Ulivi, A. Y. Chu, F. Murgia, S. Trompet, M. Imboden, B. Kollerits, G. Pistis, C. A. Consortium, I. Consortium, C. A. Consortium, C. Wellcome Trust Case Control, T. B. Harris, L. J. Launer, T. Aspelund, G. Eiriksdottir, B. D. Mitchell, E. Boerwinkle, H. Schmidt, M. Cavalieri, M. Rao, F. B. Hu, A. Demirkan, B. A. Oostra, M. de Andrade, S. T. Turner, J. Ding, J. S. Andrews, B. I. Freedman, W. Koenig, T. Illig, A. Doring, H. E. Wichmann, I. Kolcic, T. Zemunik, M. Boban, C. Minelli, H. E. Wheeler, W. Igl, G. Zaboli, S. H. Wild, A. F. Wright, H. Campbell, D. Ellinghaus, U. Nothlings, G. Jacobs, R. Biffar, K. Endlich, F. Ernst, G. Homuth, H. K. Kroemer, M. Nauck, S. Stracke, U. Volker, H. Volzke, P. Kovacs, M. Stumvoll, R. Magi, A. Hofman, A. G. Uitterlinden, F. Rivadeneira, Y. S. Aulchenko, O. Polasek, N. Hastie, V. Vitart, C. Helmer, J. J. Wang, D. Ruggiero, S. Bergmann, M. Kahonen, J. Viikari, T. Nikopensius, M. Province, S. Ketkar, H. Colhoun, A. Doney, A. Robino, F. Giulianini, B. K. Kramer, L. Portas, I. Ford, B. M. Buckley, M. Adam, G. A. Thun, B. Paulweber, M. Haun, C. Sala, M. Metzger, P. Mitchell, M. Ciullo, S. K. Kim, P. Vollenweider, O. Raitakari, A. Metspalu, C. Palmer, P. Gasparini, M. Pirastu, J. W. Jukema, N. M. Probst-Hensch, F. Kronenberg, D. Toniolo, V. Gudnason, A. R. Shuldiner, J. Coresh, R. Schmidt, L. Ferrucci, D. S. Siscovick, C. M. van Duijn, I. Borecki, S. L. Kardia, Y. Liu, G. C. Curhan, I. Rudan, U. Gyllensten, J. F. Wilson, A. Franke, P. P. Pramstaller, R. Rettig, I. Prokopenko, J. C. Witteman, C. Hayward, P. Ridker, A. Parsa, M. Bochud, I. M. Heid, W. Goessling, D. I. Chasman, W. H. Kao and C. S. Fox (2012) Genome-wide association and functional follow-up reveals new loci for kidney function PLoS Genet 8, e1002584.

O. N. Goek, A. Doring, C. Gieger, M. Heier, W. Koenig, C. Prehn, W. Romisch-Margl, R. Wang-Sattler, T. Illig, K. Suhre, P. Sekula, G. Zhai, J. Adamski, A. Kottgen and C. Meisinger (2012) Serum metabolite concentrations and decreased GFR in the general population Am J Kidney Dis 60, 197-206.

P. Dalle Pezze, A. G. Sonntag, A. Thien, M. T. Prentzell, M. Godel, S. Fischer, E. Neumann-Haefelin, T. B. Huber, R. Baumeister, D. P. Shanley and K. Thedieck (2012) A dynamic network model of mTOR signaling reveals TSC-independent mTORC2 regulation Sci Signal 5, ra25.

J. Kleffmann, V. Frank, A. Ferbert and C. Bergmann (2012) Dosage-sensitive network in polycystic kidney and liver disease: multiple mutations cause severe hepatic and neurological complications J Hepatol 57, 476-7.

K. Inoki and T. B. Huber (2012) Mammalian target of rapamycin signaling in the podocyte Curr Opin Nephrol Hypertens 21, 251-7.

O. N. Goek, A. Kottgen, R. C. Hoogeveen, C. M. Ballantyne, J. Coresh and B. C. Astor (2012) Association of apolipoprotein A1 and B with kidney function and chronic kidney disease in two multiethnic population samples Nephrol Dial Transplant 27, 2839-47.

A. Linkermann, J. H. Brasen, N. Himmerkus, S. Liu, T. B. Huber, U. Kunzendorf and S. Krautwald (2012) Rip1 (receptor-interacting protein kinase 1) mediates necroptosis and contributes to renal ischemia/reperfusion injury Kidney Int 81, 751-61.

S. Lienkamp, A. Ganner and G. Walz (2012) Inversin, Wnt signaling and primary cilia Differentiation 83, S49-55.

R. N. Rashmi, B. Eckes, G. Glockner, M. Groth, S. Neumann, J. Gloy, L. Sellin, G. Walz, M. Schneider, I. Karakesisoglou, L. Eichinger and A. A. Noegel (2012) The nuclear envelope protein Nesprin-2 has roles in cell proliferation and differentiation during wound healing Nucleus 3, 172-86.

S. Zhang, E. Condac, H. Qiu, J. Jiang, G. Gutierrez-Sanchez, C. Bergmann, T. Handel and L. Wang (2012) Heparin-induced leukocytosis requires 6-O-sulfation and is caused by blockade of selectin- and CXCL12 protein-mediated leukocyte trafficking in mice J Biol Chem 287, 5542-53.

C. Bergmann and R. Weiskirchen (2012) It's not all in the cilium, but on the road to it: genetic interaction network in polycystic kidney and liver diseases and how trafficking and quality control matter J Hepatol 56, 1201-3.

P. F. Alesina; J. Hinrichs; B. Meier; K. W. Schmid; H. P. Neumann; M. K. Walz (2012) Minimally invasive cortical-sparing surgery for bilateral pheochromocytomas Langenbecks Arch Surg 397, 233-8.

C. Bergmann (2012) Educational paper: ciliopathies Eur J Pediatr 171, 1285-300.

K. U. Eckardt, B. Barthlein, S. Baid-Agrawal, A. Beck, M. Busch, F. Eitner, A. B. Ekici, J. Floege, O. Gefeller, H. Haller, R. Hilge, K. F. Hilgers, J. T. Kielstein, V. Krane, A. Kottgen, F. Kronenberg, P. Oefner, H. U. Prokosch, A. Reis, M. Schmid, E. Schaeffner, U. T. Schultheiss, S. A. Seuchter, T. Sitter, C. Sommerer, G. Walz, C. Wanner, G. Wolf, M. Zeier and S. Titze (2012) The German Chronic Kidney Disease (GCKD) study: design and methods Nephrol Dial Transplant 27, 1454-60.

F. Brinkert, Lehnhardt, A., Montoya, C., Helmke, K., Schaefer, H., Fischer, L., Nashan, B., Bergmann, C., Ganschow, R., Kemper, M.J. (2012) Combined liver-kidney transplantation for children with autosomal recessive polycystic kidney disease (ARPKD): indication and outcome (under review).

G. Naz; S. M. Pasternack; C. Perrin; M. Mattheisen; M. Refke; S. Khan; A. Gul; M. Simons; W. Ahmad; R. C. Betz (2011) FZD6 encoding the Wnt receptor frizzled-6 is mutated in autosomal-recessive nail dysplasia Br J Dermatol.

C. A. Jilg; H. P. Neumann; S. Glasker; O. Schafer; P. U. Ardelt; M. Schwardt; W. Schultze-Seemann (2011) Growth Kinetics in Von Hippel-Lindau-Associated Renal Cell Carcinoma Urol Int.

M. Simons and T. B. Huber (2011) Old friends form alliance against podocytes Kidney Int 80, 1117-9.

C. Bergmann, J. von Bothmer, N. Ortiz Bruchle, A. Venghaus, V. Frank, H. Fehrenbach, T. Hampel, L. Pape, A. Buske, J. Jonsson, N. Sarioglu, A. Santos, J. C. Ferreira, J. U. Becker, R. Cremer, J. Hoefele, M. R. Benz, L. T. Weber, R. Buettner and K. Zerres (2011) Mutations in multiple PKD genes may explain early and severe polycystic kidney disease J Am Soc Nephrol 22, 2047-56.

F. Riediger, I. Quack, F. Qadri, B. Hartleben, J. K. Park, S. A. Potthoff, D. Sohn, G. Sihn, A. Rousselle, V. Fokuhl, U. Maschke, B. Purfurst, W. Schneider, L. C. Rump, F. C. Luft, R. Dechend, M. Bader, T. B. Huber, G. Nguyen and D. N. Muller (2011) Prorenin receptor is essential for podocyte autophagy and survival J Am Soc Nephrol 22, 2193-202.

T. D. Poeppel; A. Yuece; C. Boy; K. A. Metz; E. Kaminsky; H. P. Neumann; S. J. Rosenbaum; K. Mann; L. C. Moeller (2011) Novel SDHD gene mutation (H102R) in a patient with metastatic cervical paraganglioma effectively treated by peptide receptor radionuclide therapy J Clin Oncol 29, e812-5.

K. Dudziak; I. Rettig; P. Adam; M. Horger; H. P. Neumann; K. Mussig (2011) [Rare cause of insufficient metabolic control of diabetes mellitus - Case 10/2011] Dtsch Med Wochenschr 136, 2196.

C. A. Boger, M. Gorski, M. Li, M. M. Hoffmann, C. Huang, Q. Yang, A. Teumer, V. Krane, C. M. O'Seaghdha, Z. Kutalik, H. E. Wichmann, T. Haak, E. Boes, S. Coassin, J. Coresh, B. Kollerits, M. Haun, B. Paulweber, A. Kottgen, G. Li, M. G. Shlipak, N. Powe, S. J. Hwang, A. Dehghan, F. Rivadeneira, A. Uitterlinden, A. Hofman, J. S. Beckmann, B. K. Kramer, J. Witteman, M. Bochud, D. Siscovick, R. Rettig, F. Kronenberg, C. Wanner, R. I. Thadhani, I. M. Heid, C. S. Fox, W. H. Kao and C. K. Consortium (2011) Association of eGFR-Related Loci Identified by GWAS with Incident CKD and ESRD PLoS Genet 7, e1002292.

T. K. Hoffmann, S. Trellakis, K. Okulicz, P. Schuler, J. Greve, J. Arnolds, C. Bergmann, M. Bas, S. Lang, G. Lehnerdt, S. Brandau, S. Mattheis, K. Scheckenbach, O. J. Finn, T. L. Whiteside and E. Sonkoly (2011) Cyclin B1 expression and p53 status in squamous cell carcinomas of the head and neck Anticancer Res 31, 3151-7.

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C. Bergmann, M. Paulus and P. Fikkert (2011) Preschoolers' comprehension of pronouns and reflexives: the impact of the task J Child Lang, 1-27.

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R. Salonen, M. Kestila and C. Bergmann (2011) Clinical utility gene card for: Meckel syndrome Eur J Hum Genet 19.

M. C. Liebau, K. Hopker, R. U. Muller, I. Schmedding, S. Zank, B. Schairer, F. Fabretti, M. Hohne, M. P. Bartram, C. Dafinger, M. Hackl, V. Burst, S. Habbig, H. Zentgraf, A. Blaukat, G. Walz, T. Benzing and B. Schermer (2011) Nephrocystin-4 regulates Pyk2-induced tyrosine phosphorylation of nephrocystin-1 to control targeting to monocilia J Biol Chem 286, 14237-45.

C. A. Boger, M. H. Chen, A. Tin, M. Olden, A. Kottgen, I. H. de Boer, C. Fuchsberger, C. M. O'Seaghdha, C. Pattaro, A. Teumer, C. T. Liu, N. L. Glazer, M. Li, J. R. O'Connell, T. Tanaka, C. A. Peralta, Z. Kutalik, J. Luan, J. H. Zhao, S. J. Hwang, E. Akylbekova, H. Kramer, P. van der Harst, A. V. Smith, K. Lohman, M. de Andrade, C. Hayward, B. Kollerits, A. Tonjes, T. Aspelund, E. Ingelsson, G. Eiriksdottir, L. J. Launer, T. B. Harris, A. R. Shuldiner, B. D. Mitchell, D. E. Arking, N. Franceschini, E. Boerwinkle, J. Egan, D. Hernandez, M. Reilly, R. R. Townsend, T. Lumley, D. S. Siscovick, B. M. Psaty, B. Kestenbaum, T. Haritunians, S. Bergmann, P. Vollenweider, G. Waeber, V. Mooser, D. Waterworth, A. D. Johnson, J. C. Florez, J. B. Meigs, X. Lu, S. T. Turner, E. J. Atkinson, T. S. Leak, K. Aasarod, F. Skorpen, A. C. Syvanen, T. Illig, J. Baumert, W. Koenig, B. K. Kramer, O. Devuyst, J. C. Mychaleckyj, C. Minelli, S. J. Bakker, L. Kedenko, B. Paulweber, S. Coassin, K. Endlich, H. K. Kroemer, R. Biffar, S. Stracke, H. Volzke, M. Stumvoll, R. Magi, H. Campbell, V. Vitart, N. D. Hastie, V. Gudnason, S. L. Kardia, Y. Liu, O. Polasek, G. Curhan, F. Kronenberg, I. Prokopenko, I. Rudan, J. Arnlov, S. Hallan, G. Navis, C. K. Consortium, A. Parsa, L. Ferrucci, J. Coresh, M. G. Shlipak, S. B. Bull, N. J. Paterson, H. E. Wichmann, N. J. Wareham, R. J. Loos, J. I. Rotter, P. P. Pramstaller, L. A. Cupples, J. S. Beckmann, Q. Yang, I. M. Heid, R. Rettig, A. W. Dreisbach, M. Bochud, C. S. Fox and W. H. Kao (2011) CUBN is a gene locus for albuminuria J Am Soc Nephrol 22, 555-70.

S. Glasker; M. J. Shah; B. Hippchen; H. P. Neumann; V. Van Velthoven (2011) Doppler-Sonographically Guided Resection of CNS Hemangioblastomas Neurosurgery.

H. C. Stanescu, M. Arcos-Burgos, A. Medlar, D. Bockenhauer, A. Kottgen, L. Dragomirescu, C. Voinescu, N. Patel, K. Pearce, M. Hubank, H. A. Stephens, V. Laundy, S. Padmanabhan, A. Zawadzka, J. M. Hofstra, M. J. Coenen, M. den Heijer, L. A. Kiemeney, D. Bacq-Daian, B. Stengel, S. H. Powis, P. Brenchley, J. Feehally, A. J. Rees, H. Debiec, J. F. Wetzels, P. Ronco, P. W. Mathieson and R. Kleta (2011) Risk HLA-DQA1 and PLA(2)R1 alleles in idiopathic membranous nephropathy N Engl J Med 364, 616-26.

K. Schickle, K. Zurlinden, C. Bergmann, M. Lindner, A. Kirsten, M. Laub, R. Telle, H. Jennissen and H. Fischer (2011) Synthesis of novel tricalcium phosphate-bioactive glass composite and functionalization with rhBMP-2 J Mater Sci Mater Med 22, 763-71.

C. M. O'Seaghdha, S. J. Hwang, N. A. Bhavsar, A. Kottgen, J. Coresh, B. C. Astor and C. S. Fox (2011) Lower urinary connective tissue growth factor levels and incident CKD stage 3 in the general population Am J Kidney Dis 57, 841-9.

A. Hofherr; M. Kottgen (2011) TRPP channels and polycystins Adv Exp Med Biol 704, 287-313.

A. Hofherr and M. Kottgen (2011) TRPP channels and polycystins Adv Exp Med Biol 704, 287-313

T. Weide and T. B. Huber (2011) Implications of autophagy for glomerular aging and disease Cell Tissue Res 343, 467-73.

E. E. Davis, Q. Zhang, Q. Liu, B. H. Diplas, L. M. Davey, J. Hartley, C. Stoetzel, K. Szymanska, G. Ramaswami, C. V. Logan, D. M. Muzny, A. C. Young, D. A. Wheeler, P. Cruz, M. Morgan, L. R. Lewis, P. Cherukuri, B. Maskeri, N. F. Hansen, J. C. Mullikin, R. W. Blakesley, G. G. Bouffard, G. Gyapay, S. Rieger, B. Tonshoff, I. Kern, N. A. Soliman, T. J. Neuhaus, K. J. Swoboda, H. Kayserili, T. E. Gallagher, R. A. Lewis, C. Bergmann, E. A. Otto, S. Saunier, P. J. Scambler, P. L. Beales, J. G. Gleeson, E. R. Maher, T. Attie-Bitach, H. Dollfus, C. A. Johnson, E. D. Green, R. A. Gibbs, F. Hildebrandt, E. A. Pierce and N. Katsanis (2011) TTC21B contributes both causal and modifying alleles across the ciliopathy spectrum Nat Genet 43, 189-96.

A. K. Teo, S. J. Arnold, M. W. Trotter, S. Brown, L. T. Ang, Z. Chng, E. J. Robertson, N. R. Dunn and L. Vallier (2011) Pluripotency factors regulate definitive endoderm specification through eomesodermin Genes Dev 25, 238-50.

B. George, B. Vollenbroker, M. A. Saleem, T. B. Huber, H. Pavenstadt and T. Weide (2011) GSK3beta inactivation in podocytes results in decreased phosphorylation of p70S6K accompanied by cytoskeletal rearrangements and inhibited motility Am J Physiol Renal Physiol 300, F1152-62.

L. von Ducker; M. K. Walz; C. Voss; G. Arnold; C. Eng; H. P. Neumann (2011) Laparoscopic organ-sparing resection of von Hippel-Lindau disease-associated pancreatic neuroendocrine tumors World J Surg 35, 563-7.

M. A. McAdams, J. W. Maynard, A. N. Baer, A. Kottgen, S. Clipp, J. Coresh and A. C. Gelber (2011) Reliability and sensitivity of the self-report of physician-diagnosed gout in the campaign against cancer and heart disease and the atherosclerosis risk in the community cohorts J Rheumatol 38, 135-41.

T. B. Huber, G. Walz and E. W. Kuehn (2011) mTOR and rapamycin in the kidney: signaling and therapeutic implications beyond immunosuppression Kidney Int 79, 502-11.

M. Kottgen; T. Benzing (2011) Strangers on a train: atypical glutamate receptors in the kidney glomerulus. Focus on "Functional NMDA receptors with atypical properties are expressed in podocytes" Am J Physiol Cell Physiol 300, C9-10.

M. Kottgen and T. Benzing (2011) Strangers on a train: atypical glutamate receptors in the kidney glomerulus. Focus on "Functional NMDA receptors with atypical properties are expressed in podocytes" Am J Physiol Cell Physiol 300, C9-10

M. Geyer, J. Wilpert, T. Wiech, C. Theilacker, M. Stubanus, A. Kramer-Zucker, K. G. Fischer, O. Drognitz, A. Frydrychowicz, W. Kern, G. Walz and P. Pisarski (2011) Rapidly progressive hepatic alveolar echinococcosis in an ABO-incompatible renal transplant recipient Transpl Infect Dis 13, 278-84.

J. Kremerskothen, M. Stolting, C. Wiesner, A. Korb-Pap, V. van Vliet, S. Linder, T. B. Huber, P. Rottiers, E. Reuzeau, E. Genot and H. Pavenstadt (2011) Zona occludens proteins modulate podosome formation and function FASEB J 25, 505-14.

K. Evans, J. Coresh, L. D. Bash, T. Gary-Webb, A. Kottgen, K. Carson and L. E. Boulware (2011) Race differences in access to health care and disparities in incident chronic kidney disease in the US Nephrol Dial Transplant 26, 899-908.

C. Papewalis; C. Kouatchoua; M. Ehlers; B. Jacobs; D. Porwol; S. Schinner; H. S. Willenberg; M. Anlauf; A. Raffel; G. Eisenhofer; H. P. Neumann; S. R. Bornstein; W. A. Scherbaum; M. Schott (2011) Chromogranin A as potential target for immunotherapy of malignant pheochromocytoma Mol Cell Endocrinol 335, 69-77.

C. Bergmann, S. Spranger, P. Javaher and M. Ptok (2011) Genitopatellar syndrome, sensorineural hearing loss, and cleft palate Oral Maxillofac Surg 15, 103-6.

G. Walz; K. Budde; K. U. Eckardt (2011) mTOR inhibitors and autosomal dominant polycystic kidney disease (authors reply) N Engl J Med 364, 287-288.

N. Sotoodehnia, A. Isaacs, P. I. de Bakker, M. Dorr, C. Newton-Cheh, I. M. Nolte, P. van der Harst, M. Muller, M. Eijgelsheim, A. Alonso, A. A. Hicks, S. Padmanabhan, C. Hayward, A. V. Smith, O. Polasek, S. Giovannone, J. Fu, J. W. Magnani, K. D. Marciante, A. Pfeufer, S. A. Gharib, A. Teumer, M. Li, J. C. Bis, F. Rivadeneira, T. Aspelund, A. Kottgen, T. Johnson, K. Rice, M. P. Sie, Y. A. Wang, N. Klopp, C. Fuchsberger, S. H. Wild, I. Mateo Leach, K. Estrada, U. Volker, A. F. Wright, F. W. Asselbergs, J. Qu, A. Chakravarti, M. F. Sinner, J. A. Kors, A. Petersmann, T. B. Harris, E. Z. Soliman, P. B. Munroe, B. M. Psaty, B. A. Oostra, L. A. Cupples, S. Perz, R. A. de Boer, A. G. Uitterlinden, H. Volzke, T. D. Spector, F. Y. Liu, E. Boerwinkle, A. F. Dominiczak, J. I. Rotter, G. van Herpen, D. Levy, H. E. Wichmann, W. H. van Gilst, J. C. Witteman, H. K. Kroemer, W. H. Kao, S. R. Heckbert, T. Meitinger, A. Hofman, H. Campbell, A. R. Folsom, D. J. van Veldhuisen, C. Schwienbacher, C. J. O'Donnell, C. B. Volpato, M. J. Caulfield, J. M. Connell, L. Launer, X. Lu, L. Franke, R. S. Fehrmann, G. te Meerman, H. J. Groen, R. K. Weersma, L. H. van den Berg, C. Wijmenga, R. A. Ophoff, G. Navis, I. Rudan, H. Snieder, J. F. Wilson, P. P. Pramstaller, D. S. Siscovick, T. J. Wang, V. Gudnason, C. M. van Duijn, S. B. Felix, G. I. Fishman, Y. Jamshidi, B. H. Stricker, N. J. Samani, S. Kaab and D. E. Arking (2010) Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction Nat Genet 42, 1068-76.

S. Lienkamp, A. Ganner, C. Boehlke, T. Schmidt, S. J. Arnold, T. Schafer, D. Romaker, J. Schuler, S. Hoff, C. Powelske, A. Eifler, C. Kronig, A. Bullerkotte, R. Nitschke, E. W. Kuehn, E. Kim, H. Burkhardt, T. Brox, O. Ronneberger, J. Gloy and G. Walz (2010) Inversin relays Frizzled-8 signals to promote proximal pronephros development Proc Natl Acad Sci U S A 107, 20388-93.

C. Boehlke, F. Kotsis, V. Patel, S. Braeg, H. Voelker, S. Bredt, T. Beyer, H. Janusch, C. Hamann, M. Godel, K. Muller, M. Herbst, M. Hornung, M. Doerken, M. Kottgen, R. Nitschke, P. Igarashi, G. Walz and E. W. Kuehn (2010) Primary cilia regulate mTORC1 activity and cell size through Lkb1 Nat Cell Biol 12, 1115-22.

J. P. Drenth, M. Chrispijn and C. Bergmann (2010) Congenital fibrocystic liver diseases Best Pract Res Clin Gastroenterol 24, 573-84.

Q. Yang, A. Kottgen, A. Dehghan, A. V. Smith, N. L. Glazer, M. H. Chen, D. I. Chasman, T. Aspelund, G. Eiriksdottir, T. B. Harris, L. Launer, M. Nalls, D. Hernandez, D. E. Arking, E. Boerwinkle, M. L. Grove, M. Li, W. H. Linda Kao, M. Chonchol, T. Haritunians, G. Li, T. Lumley, B. M. Psaty, M. Shlipak, S. J. Hwang, M. G. Larson, C. J. O'Donnell, A. Upadhyay, C. M. van Duijn, A. Hofman, F. Rivadeneira, B. Stricker, A. G. Uitterlinden, G. Pare, A. N. Parker, P. M. Ridker, D. S. Siscovick, V. Gudnason, J. C. Witteman, C. S. Fox and J. Coresh (2010) Multiple genetic loci influence serum urate levels and their relationship with gout and cardiovascular disease risk factors Circ Cardiovasc Genet 3, 523-30.

N. Soranzo, S. Sanna, E. Wheeler, C. Gieger, D. Radke, J. Dupuis, N. Bouatia-Naji, C. Langenberg, I. Prokopenko, E. Stolerman, M. S. Sandhu, M. M. Heeney, J. M. Devaney, M. P. Reilly, S. L. Ricketts, A. F. Stewart, B. F. Voight, C. Willenborg, B. Wright, D. Altshuler, D. Arking, B. Balkau, D. Barnes, E. Boerwinkle, B. Bohm, A. Bonnefond, L. L. Bonnycastle, D. I. Boomsma, S. R. Bornstein, Y. Bottcher, S. Bumpstead, M. S. Burnett-Miller, H. Campbell, A. Cao, J. Chambers, R. Clark, F. S. Collins, J. Coresh, E. J. de Geus, M. Dei, P. Deloukas, A. Doring, J. M. Egan, R. Elosua, L. Ferrucci, N. Forouhi, C. S. Fox, C. Franklin, M. G. Franzosi, S. Gallina, A. Goel, J. Graessler, H. Grallert, A. Greinacher, D. Hadley, A. Hall, A. Hamsten, C. Hayward, S. Heath, C. Herder, G. Homuth, J. J. Hottenga, R. Hunter-Merrill, T. Illig, A. U. Jackson, A. Jula, M. Kleber, C. W. Knouff, A. Kong, J. Kooner, A. Kottgen, P. Kovacs, K. Krohn, B. Kuhnel, J. Kuusisto, M. Laakso, M. Lathrop, C. Lecoeur, M. Li, M. Li, R. J. Loos, J. Luan, V. Lyssenko, R. Magi, P. K. Magnusson, A. Malarstig, M. Mangino, M. T. Martinez-Larrad, W. Marz, W. L. McArdle, R. McPherson, C. Meisinger, T. Meitinger, O. Melander, K. L. Mohlke, V. E. Mooser, M. A. Morken, N. Narisu, D. M. Nathan, M. Nauck, C. O'Donnell, K. Oexle, N. Olla, J. S. Pankow, F. Payne, J. F. Peden, N. L. Pedersen, L. Peltonen, M. Perola, O. Polasek, E. Porcu, D. J. Rader, W. Rathmann, S. Ripatti, G. Rocheleau, M. Roden, I. Rudan, V. Salomaa, R. Saxena, D. Schlessinger, H. Schunkert, P. Schwarz, U. Seedorf, E. Selvin, M. Serrano-Rios, P. Shrader, A. Silveira, D. Siscovick, K. Song, T. D. Spector, K. Stefansson, V. Steinthorsdottir, D. P. Strachan, R. Strawbridge, M. Stumvoll, I. Surakka, A. J. Swift, T. Tanaka, A. Teumer, G. Thorleifsson, U. Thorsteinsdottir, A. Tonjes, G. Usala, V. Vitart, H. Volzke, H. Wallaschofski, D. M. Waterworth, H. Watkins, H. E. Wichmann, S. H. Wild, G. Willemsen, G. H. Williams, J. F. Wilson, J. Winkelmann, A. F. Wright, Wtccc, C. Zabena, J. H. Zhao, S. E. Epstein, J. Erdmann, H. H. Hakonarson, S. Kathiresan, K. T. Khaw, R. Roberts, N. J. Samani, M. D. Fleming, R. Sladek, G. Abecasis, M. Boehnke, P. Froguel, L. Groop, M. I. McCarthy, W. H. Kao, J. C. Florez, M. Uda, N. J. Wareham, I. Barroso and J. B. Meigs (2010) Common variants at 10 genomic loci influence hemoglobin A(1)(C) levels via glycemic and nonglycemic pathways Diabetes 59, 3229-39.

L. J. Rasmussen-Torvik, A. Alonso, M. Li, W. Kao, A. Kottgen, Y. Yan, D. Couper, E. Boerwinkle, S. J. Bielinski and J. S. Pankow (2010) Impact of repeated measures and sample selection on genome-wide association studies of fasting glucose Genet Epidemiol 34, 665-73.

E. A. Otto, T. W. Hurd, R. Airik, M. Chaki, W. Zhou, C. Stoetzel, S. B. Patil, S. Levy, A. K. Ghosh, C. A. Murga-Zamalloa, J. van Reeuwijk, S. J. Letteboer, L. Sang, R. H. Giles, Q. Liu, K. L. Coene, A. Estrada-Cuzcano, R. W. Collin, H. M. McLaughlin, S. Held, J. M. Kasanuki, G. Ramaswami, J. Conte, I. Lopez, J. Washburn, J. Macdonald, J. Hu, Y. Yamashita, E. R. Maher, L. M. Guay-Woodford, H. P. Neumann, N. Obermuller, R. K. Koenekoop, C. Bergmann, X. Bei, R. A. Lewis, N. Katsanis, V. Lopes, D. S. Williams, R. H. Lyons, C. V. Dang, D. A. Brito, M. B. Dias, X. Zhang, J. D. Cavalcoli, G. Nurnberg, P. Nurnberg, E. A. Pierce, P. K. Jackson, C. Antignac, S. Saunier, R. Roepman, H. Dollfus, H. Khanna and F. Hildebrandt (2010) Candidate exome capture identifies mutation of SDCCAG8 as the cause of a retinal-renal ciliopathy Nat Genet 42, 840-50.

N. Wohllk; H. Schweizer; Z. Erlic; K. W. Schmid; M. K. Walz; F. Raue; H. P. Neumann (2010) Multiple endocrine neoplasia type 2 Best Pract Res Clin Endocrinol Metab 24, 371-87.

S. Akoudad, M. Szklo, M. A. McAdams, T. Fulop, C. A. Anderson, J. Coresh and A. Kottgen (2010) Correlates of kidney stone disease differ by race in a multi-ethnic middle-aged population: the ARIC study Prev Med 51, 416-20.

A. M. Kucharska-Newton, K. L. Monda, S. J. Bielinski, E. Boerwinkle, T. D. Rea, W. D. Rosamond, J. S. Pankow, A. Kottgen, G. Heiss and K. E. North (2010) Role of BMI in the Association of the TCF7L2 rs7903146 Variant with Coronary Heart Disease: The Atherosclerosis Risk in Communities (ARIC) Study J Obes 2010.

A. Kottgen (2010) Genome-wide association studies in nephrology research Am J Kidney Dis 56, 743-58.

C. M. O'Seaghdha, Q. Yang, N. L. Glazer, T. S. Leak, A. Dehghan, A. V. Smith, W. H. Kao, K. Lohman, S. J. Hwang, A. D. Johnson, A. Hofman, A. G. Uitterlinden, Y. D. Chen, G. Consortium, E. M. Brown, D. S. Siscovick, T. B. Harris, B. M. Psaty, J. Coresh, V. Gudnason, J. C. Witteman, Y. M. Liu, B. R. Kestenbaum, C. S. Fox and A. Kottgen (2010) Common variants in the calcium-sensing receptor gene are associated with total serum calcium levels Hum Mol Genet 19, 4296-303.

H. Schweizer; J. Boehm; J. T. Winterer; D. Wild; H. P. Neumann; T. Wiech; M. Stubanus; E. W. Kuehn (2010) Phaeochromocytoma and thrombotic microangiopathy: favourable outcome despite advanced renal failure J Clin Pathol 63, 754-6.

T. E. Meyer, G. C. Verwoert, S. J. Hwang, N. L. Glazer, A. V. Smith, F. J. van Rooij, G. B. Ehret, E. Boerwinkle, J. F. Felix, T. S. Leak, T. B. Harris, Q. Yang, A. Dehghan, T. Aspelund, R. Katz, G. Homuth, T. Kocher, R. Rettig, J. S. Ried, C. Gieger, H. Prucha, A. Pfeufer, T. Meitinger, J. Coresh, A. Hofman, M. J. Sarnak, Y. D. Chen, A. G. Uitterlinden, A. Chakravarti, B. M. Psaty, C. M. van Duijn, W. H. Kao, J. C. Witteman, V. Gudnason, D. S. Siscovick, C. S. Fox, A. Kottgen, C. Genetic Factors for Osteoporosis, G. Meta Analysis of and C. Insulin Related Traits (2010) Genome-wide association studies of serum magnesium, potassium, and sodium concentrations identify six Loci influencing serum magnesium levels PLoS Genet 6.

M. Bi, W. H. Kao, E. Boerwinkle, R. C. Hoogeveen, L. J. Rasmussen-Torvik, B. C. Astor, K. E. North, J. Coresh and A. Kottgen (2010) Association of rs780094 in GCKR with metabolic traits and incident diabetes and cardiovascular disease: the ARIC Study PLoS One 5, e11690.

Z. Erlic; U. Ploeckinger; A. Cascon; M. M. Hoffmann; L. von Duecker; A. Winter; G. Kammel; J. Bacher; M. Sullivan; B. Isermann; L. Fischer; A. Raffel; W. T. Knoefel; M. Schott; T. Baumann; O. Schaefer; T. Keck; R. P. Baum; I. Milos; M. Muresan; M. Peczkowska; A. Januszewicz; K. Cupisti; A. Tonjes; M. Fasshauer; J. Langrehr; P. von Wussow; A. Agaimy; G. Schlimok; R. Lamberts; T. Wiech; K. W. Schmid; A. Weber; M. Nunez; M. Robledo; C. Eng; H. P. Neumann (2010) Systematic comparison of sporadic and syndromic pancreatic islet cell tumors Endocr Relat Cancer 17, 875-83.

G. Walz, K. Budde, M. Mannaa, J. Nurnberger, C. Wanner, C. Sommerer, U. Kunzendorf, B. Banas, W. H. Horl, N. Obermuller, W. Arns, H. Pavenstadt, J. Gaedeke, M. Buchert, C. May, H. Gschaidmeier, S. Kramer and K. U. Eckardt (2010) Everolimus in patients with autosomal dominant polycystic kidney disease N Engl J Med 363, 830-40.

T. Hermle, D. Saltukoglu, J. Grunewald, G. Walz and M. Simons (2010) Regulation of Frizzled-dependent planar polarity signaling by a V-ATPase subunit Curr Biol 20, 1269-76.

B. Kestenbaum, N. L. Glazer, A. Kottgen, J. F. Felix, S. J. Hwang, Y. Liu, K. Lohman, S. B. Kritchevsky, D. B. Hausman, A. K. Petersen, C. Gieger, J. S. Ried, T. Meitinger, T. M. Strom, H. E. Wichmann, H. Campbell, C. Hayward, I. Rudan, I. H. de Boer, B. M. Psaty, K. M. Rice, Y. D. Chen, M. Li, D. E. Arking, E. Boerwinkle, J. Coresh, Q. Yang, D. Levy, F. J. van Rooij, A. Dehghan, F. Rivadeneira, A. G. Uitterlinden, A. Hofman, C. M. van Duijn, M. G. Shlipak, W. H. Kao, J. C. Witteman, D. S. Siscovick and C. S. Fox (2010) Common genetic variants associate with serum phosphorus concentration J Am Soc Nephrol 21, 1223-32.

H. P. Neumann (2010) [Machina Machinarum. The clock as a concept and metaphor between 1450 and 1750] Early Sci Med 15, 122-91.

Y. Yan, R. Klein, G. Heiss, C. J. Girman, E. M. Lange, B. E. Klein, K. M. Rose, E. Boerwinkle, J. S. Pankow, F. L. Brancati, C. M. Ballantyne, A. Kottgen and K. E. North (2010) The transcription factor 7-like 2 (TCF7L2) polymorphism may be associated with focal arteriolar narrowing in Caucasians with hypertension or without diabetes: the ARIC Study BMC Endocr Disord 10, 9.

J. Wilpert, K. G. Fischer, P. Pisarski, T. Wiech, M. Daskalakis, A. Ziegler, E. Neumann-Haefelin, O. Drognitz, F. Emmerich, G. Walz and M. Geyer (2010) Long-term outcome of ABO-incompatible living donor kidney transplantation based on antigen-specific desensitization. An observational comparative analysis Nephrol Dial Transplant 25, 3778-86.

K. Yamagishi, T. Tanigawa, A. Kitamura, A. Kottgen, A. R. Folsom, H. Iso and C. Investigators (2010) The rs2231142 variant of the ABCG2 gene is associated with uric acid levels and gout among Japanese people Rheumatology (Oxford) 49, 1461-5.

A. Kottgen, C. Pattaro, C. A. Boger, C. Fuchsberger, M. Olden, N. L. Glazer, A. Parsa, X. Gao, Q. Yang, A. V. Smith, J. R. O'Connell, M. Li, H. Schmidt, T. Tanaka, A. Isaacs, S. Ketkar, S. J. Hwang, A. D. Johnson, A. Dehghan, A. Teumer, G. Pare, E. J. Atkinson, T. Zeller, K. Lohman, M. C. Cornelis, N. M. Probst-Hensch, F. Kronenberg, A. Tonjes, C. Hayward, T. Aspelund, G. Eiriksdottir, L. J. Launer, T. B. Harris, E. Rampersaud, B. D. Mitchell, D. E. Arking, E. Boerwinkle, M. Struchalin, M. Cavalieri, A. Singleton, F. Giallauria, J. Metter, I. H. de Boer, T. Haritunians, T. Lumley, D. Siscovick, B. M. Psaty, M. C. Zillikens, B. A. Oostra, M. Feitosa, M. Province, M. de Andrade, S. T. Turner, A. Schillert, A. Ziegler, P. S. Wild, R. B. Schnabel, S. Wilde, T. F. Munzel, T. S. Leak, T. Illig, N. Klopp, C. Meisinger, H. E. Wichmann, W. Koenig, L. Zgaga, T. Zemunik, I. Kolcic, C. Minelli, F. B. Hu, A. Johansson, W. Igl, G. Zaboli, S. H. Wild, A. F. Wright, H. Campbell, D. Ellinghaus, S. Schreiber, Y. S. Aulchenko, J. F. Felix, F. Rivadeneira, A. G. Uitterlinden, A. Hofman, M. Imboden, D. Nitsch, A. Brandstatter, B. Kollerits, L. Kedenko, R. Magi, M. Stumvoll, P. Kovacs, M. Boban, S. Campbell, K. Endlich, H. Volzke, H. K. Kroemer, M. Nauck, U. Volker, O. Polasek, V. Vitart, S. Badola, A. N. Parker, P. M. Ridker, S. L. Kardia, S. Blankenberg, Y. Liu, G. C. Curhan, A. Franke, T. Rochat, B. Paulweber, I. Prokopenko, W. Wang, V. Gudnason, A. R. Shuldiner, J. Coresh, R. Schmidt, L. Ferrucci, M. G. Shlipak, C. M. van Duijn, I. Borecki, B. K. Kramer, I. Rudan, U. Gyllensten, J. F. Wilson, J. C. Witteman, P. P. Pramstaller, R. Rettig, N. Hastie, D. I. Chasman, W. H. Kao, I. M. Heid and C. S. Fox (2010) New loci associated with kidney function and chronic kidney disease Nat Genet 42, 376-84.

C. Boehlke, M. Bashkurov, A. Buescher, T. Krick, A. K. John, R. Nitschke, G. Walz and E. W. Kuehn (2010) Differential role of Rab proteins in ciliary trafficking: Rab23 regulates smoothened levels J Cell Sci 123, 1460-7.

E. Neumann-Haefelin, A. Kramer-Zucker, K. Slanchev, B. Hartleben, F. Noutsou, K. Martin, N. Wanner, A. Ritter, M. Godel, P. Pagel, X. Fu, A. Muller, R. Baumeister, G. Walz and T. B. Huber (2010) A model organism approach: defining the role of Neph proteins as regulators of neuron and kidney morphogenesis Hum Mol Genet 19, 2347-59.

S. Glasker; J. H. Klingler; K. Muller; C. Wurtenberger; C. Hader; J. Zentner; H. P. Neumann; V. V. Velthoven (2010) Essentials and pitfalls in the treatment of CNS hemangioblastomas and von Hippel-Lindau disease Cen Eur Neurosurg 71, 80-7.

M. Gerner, R. Haribaskar, M. Putz, J. Czerwitzki, G. Walz and T. Schafer (2010) The retinitis pigmentosa GTPase regulator interacting protein 1 (RPGRIP1) links RPGR to the nephronophthisis protein network Kidney Int 77, 891-6.

B. Hartleben, M. Godel, C. Meyer-Schwesinger, S. Liu, T. Ulrich, S. Kobler, T. Wiech, F. Grahammer, S. J. Arnold, M. T. Lindenmeyer, C. D. Cohen, H. Pavenstadt, D. Kerjaschki, N. Mizushima, A. S. Shaw, G. Walz and T. B. Huber (2010) Autophagy influences glomerular disease susceptibility and maintains podocyte homeostasis in aging mice J Clin Invest 120, 1084-96.

M. M. Estrella, B. C. Astor, A. Kottgen, E. Selvin, J. Coresh and R. S. Parekh (2010) Prevalence of kidney disease in anaemia differs by GFR-estimating method: the Third National Health and Nutrition Examination Survey (1988-94) Nephrol Dial Transplant 25, 2542-8.

P. T. Ellinor, K. L. Lunetta, N. L. Glazer, A. Pfeufer, A. Alonso, M. K. Chung, M. F. Sinner, P. I. de Bakker, M. Mueller, S. A. Lubitz, E. Fox, D. Darbar, N. L. Smith, J. D. Smith, R. B. Schnabel, E. Z. Soliman, K. M. Rice, D. R. Van Wagoner, B. M. Beckmann, C. van Noord, K. Wang, G. B. Ehret, J. I. Rotter, S. L. Hazen, G. Steinbeck, A. V. Smith, L. J. Launer, T. B. Harris, S. Makino, M. Nelis, D. J. Milan, S. Perz, T. Esko, A. Kottgen, S. Moebus, C. Newton-Cheh, M. Li, S. Mohlenkamp, T. J. Wang, W. H. Kao, R. S. Vasan, M. M. Nothen, C. A. MacRae, B. H. Stricker, A. Hofman, A. G. Uitterlinden, D. Levy, E. Boerwinkle, A. Metspalu, E. J. Topol, A. Chakravarti, V. Gudnason, B. M. Psaty, D. M. Roden, T. Meitinger, H. E. Wichmann, J. C. Witteman, J. Barnard, D. E. Arking, E. J. Benjamin, S. R. Heckbert and S. Kaab (2010) Common variants in KCNN3 are associated with lone atrial fibrillation Nat Genet 42, 240-4.

S. C. Bhakdi; A. Ottinger; S. Somsri; P. Sratongno; P. Pannadaporn; P. Chimma; P. Malasit; K. Pattanapanyasat; H. P. Neumann (2010) Optimized high gradient magnetic separation for isolation of Plasmodium-infected red blood cells Malar J 9, 38.

R. Saxena, M. F. Hivert, C. Langenberg, T. Tanaka, J. S. Pankow, P. Vollenweider, V. Lyssenko, N. Bouatia-Naji, J. Dupuis, A. U. Jackson, W. H. Kao, M. Li, N. L. Glazer, A. K. Manning, J. Luan, H. M. Stringham, I. Prokopenko, T. Johnson, N. Grarup, T. W. Boesgaard, C. Lecoeur, P. Shrader, J. O'Connell, E. Ingelsson, D. J. Couper, K. Rice, K. Song, C. H. Andreasen, C. Dina, A. Kottgen, O. Le Bacquer, F. Pattou, J. Taneera, V. Steinthorsdottir, D. Rybin, K. Ardlie, M. Sampson, L. Qi, M. van Hoek, M. N. Weedon, Y. S. Aulchenko, B. F. Voight, H. Grallert, B. Balkau, R. N. Bergman, S. J. Bielinski, A. Bonnefond, L. L. Bonnycastle, K. Borch-Johnsen, Y. Bottcher, E. Brunner, T. A. Buchanan, S. J. Bumpstead, C. Cavalcanti-Proenca, G. Charpentier, Y. D. Chen, P. S. Chines, F. S. Collins, M. Cornelis, J. C. G, J. Delplanque, A. Doney, J. M. Egan, M. R. Erdos, M. Firmann, N. G. Forouhi, C. S. Fox, M. O. Goodarzi, J. Graessler, A. Hingorani, B. Isomaa, T. Jorgensen, M. Kivimaki, P. Kovacs, K. Krohn, M. Kumari, T. Lauritzen, C. Levy-Marchal, V. Mayor, J. B. McAteer, D. Meyre, B. D. Mitchell, K. L. Mohlke, M. A. Morken, N. Narisu, C. N. Palmer, R. Pakyz, L. Pascoe, F. Payne, D. Pearson, W. Rathmann, A. Sandbaek, A. A. Sayer, L. J. Scott, S. J. Sharp, E. Sijbrands, A. Singleton, D. S. Siscovick, N. L. Smith, T. Sparso, A. J. Swift, H. Syddall, G. Thorleifsson, A. Tonjes, T. Tuomi, J. Tuomilehto, T. T. Valle, G. Waeber, A. Walley, D. M. Waterworth, E. Zeggini, J. H. Zhao, G. consortium, M. investigators, T. Illig, H. E. Wichmann, J. F. Wilson, C. van Duijn, F. B. Hu, A. D. Morris, T. M. Frayling, A. T. Hattersley, U. Thorsteinsdottir, K. Stefansson, P. Nilsson, A. C. Syvanen, A. R. Shuldiner, M. Walker, S. R. Bornstein, P. Schwarz, G. H. Williams, D. M. Nathan, J. Kuusisto, M. Laakso, C. Cooper, M. Marmot, L. Ferrucci, V. Mooser, M. Stumvoll, R. J. Loos, D. Altshuler, B. M. Psaty, J. I. Rotter, E. Boerwinkle, T. Hansen, O. Pedersen, J. C. Florez, M. I. McCarthy, M. Boehnke, I. Barroso, R. Sladek, P. Froguel, J. B. Meigs, L. Groop, N. J. Wareham and R. M. Watanabe (2010) Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge Nat Genet 42, 142-8.

A. Pfeufer, C. van Noord, K. D. Marciante, D. E. Arking, M. G. Larson, A. V. Smith, K. V. Tarasov, M. Muller, N. Sotoodehnia, M. F. Sinner, G. C. Verwoert, M. Li, W. H. Kao, A. Kottgen, J. Coresh, J. C. Bis, B. M. Psaty, K. Rice, J. I. Rotter, F. Rivadeneira, A. Hofman, J. A. Kors, B. H. Stricker, A. G. Uitterlinden, C. M. van Duijn, B. M. Beckmann, W. Sauter, C. Gieger, S. A. Lubitz, C. Newton-Cheh, T. J. Wang, J. W. Magnani, R. B. Schnabel, M. K. Chung, J. Barnard, J. D. Smith, D. R. Van Wagoner, R. S. Vasan, T. Aspelund, G. Eiriksdottir, T. B. Harris, L. J. Launer, S. S. Najjar, E. Lakatta, D. Schlessinger, M. Uda, G. R. Abecasis, B. Muller-Myhsok, G. B. Ehret, E. Boerwinkle, A. Chakravarti, E. Z. Soliman, K. L. Lunetta, S. Perz, H. E. Wichmann, T. Meitinger, D. Levy, V. Gudnason, P. T. Ellinor, S. Sanna, S. Kaab, J. C. Witteman, A. Alonso, E. J. Benjamin and S. R. Heckbert (2010) Genome-wide association study of PR interval Nat Genet 42, 153-9.

M. Sullivan; Z. Erlic; M. M. Hoffmann; K. Arbeiter; L. Patzer; K. Budde; B. Hoppe; M. Zeier; K. Lhotta; L. A. Rybicki; A. Bock; G. Berisha; H. P. Neumann (2010) Epidemiological approach to identifying genetic predispositions for atypical hemolytic uremic syndrome Ann Hum Genet 74, 17-26.

H. Peng, U. Lewandrowski, B. Muller, A. Sickmann, G. Walz and T. Wegierski (2010) Identification of a Protein Kinase C-dependent phosphorylation site involved in sensitization of TRPV4 channel Biochem Biophys Res Commun 391, 1721-5.

A. Kottgen, S. J. Hwang, M. G. Larson, J. E. Van Eyk, Q. Fu, E. J. Benjamin, A. Dehghan, N. L. Glazer, W. H. Kao, T. B. Harris, V. Gudnason, M. G. Shlipak, Q. Yang, J. Coresh, D. Levy and C. S. Fox (2010) Uromodulin levels associate with a common UMOD variant and risk for incident CKD J Am Soc Nephrol 21, 337-44.

G. Walz and E. Kim (2010) Wnt signaling and rejuvenation of the adult kidney Nephrol Dial Transplant 25, 34-6.

Z. Erlic; M. M. Hoffmann; M. Sullivan; G. Franke; M. Peczkowska; I. Harsch; M. Schott; H. E. Gabbert; M. Valimaki; S. F. Preuss; K. Hasse-Lazar; D. Waligorski; M. Robledo; A. Januszewicz; C. Eng; H. P. Neumann (2010) Pathogenicity of DNA variants and double mutations in multiple endocrine neoplasia type 2 and von Hippel-Lindau syndrome J Clin Endocrinol Metab 95, 308-13.

H. Gao, Y. Wang, T. Wegierski, K. Skouloudaki, M. Putz, X. Fu, C. Engel, C. Boehlke, H. Peng, E. W. Kuehn, E. Kim, A. Kramer-Zucker and G. Walz (2010) PRKCSH/80K-H, the protein mutated in polycystic liver disease, protects polycystin-2/TRPP2 against HERP-mediated degradation Hum Mol Genet 19, 16-24.

K. M. Kreusel; L. Krause; L. Graul-Neumann; N. E. Bechrakis; H. P. Neumann; M. H. Foerster (2009) [Family screening in patients with retinal angiomatosis] Klin Monbl Augenheilkd 226, 939-43.

S. K. Ganesh, N. A. Zakai, F. J. van Rooij, N. Soranzo, A. V. Smith, M. A. Nalls, M. H. Chen, A. Kottgen, N. L. Glazer, A. Dehghan, B. Kuhnel, T. Aspelund, Q. Yang, T. Tanaka, A. Jaffe, J. C. Bis, G. C. Verwoert, A. Teumer, C. S. Fox, J. M. Guralnik, G. B. Ehret, K. Rice, J. F. Felix, A. Rendon, G. Eiriksdottir, D. Levy, K. V. Patel, E. Boerwinkle, J. I. Rotter, A. Hofman, J. G. Sambrook, D. G. Hernandez, G. Zheng, S. Bandinelli, A. B. Singleton, J. Coresh, T. Lumley, A. G. Uitterlinden, J. M. Vangils, L. J. Launer, L. A. Cupples, B. A. Oostra, J. J. Zwaginga, W. H. Ouwehand, S. L. Thein, C. Meisinger, P. Deloukas, M. Nauck, T. D. Spector, C. Gieger, V. Gudnason, C. M. van Duijn, B. M. Psaty, L. Ferrucci, A. Chakravarti, A. Greinacher, C. J. O'Donnell, J. C. Witteman, S. Furth, M. Cushman, T. B. Harris and J. P. Lin (2009) Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium Nat Genet 41, 1191-8.

S. J. Arnold, J. Sugnaseelan, M. Groszer, S. Srinivas and E. J. Robertson (2009) Generation and analysis of a mouse line harboring GFP in the Eomes/Tbr2 locus Genesis 47, 775-81.

Z. Erlic; L. Rybicki; M. Peczkowska; H. Golcher; P. H. Kann; M. Brauckhoff; K. Mussig; M. Muresan; A. Schaffler; N. Reisch; M. Schott; M. Fassnacht; G. Opocher; S. Klose; C. Fottner; F. Forrer; U. Plockinger; S. Petersenn; D. Zabolotny; O. Kollukch; S. Yaremchuk; A. Januszewicz; M. K. Walz; C. Eng; H. P. Neumann (2009) Clinical predictors and algorithm for the genetic diagnosis of pheochromocytoma patients Clin Cancer Res 15, 6378-85.

J. Gaal; F. H. van Nederveen; Z. Erlic; E. Korpershoek; R. Oldenburg; C. C. Boedeker; U. Kontny; H. P. Neumann; W. N. Dinjens; R. R. de Krijger (2009) Parasympathetic paragangliomas are part of the Von Hippel-Lindau syndrome J Clin Endocrinol Metab 94, 4367-71.

A. Ganner, S. Lienkamp, T. Schafer, D. Romaker, T. Wegierski, T. J. Park, S. Spreitzer, M. Simons, J. Gloy, E. Kim, J. B. Wallingford and G. Walz (2009) Regulation of ciliary polarity by the APC/C Proc Natl Acad Sci U S A 106, 17799-804.

M. A. Morgan, E. Magnusdottir, T. C. Kuo, C. Tunyaplin, J. Harper, S. J. Arnold, K. Calame, E. J. Robertson and E. K. Bikoff (2009) Blimp-1/Prdm1 alternative promoter usage during mouse development and plasma cell differentiation Mol Cell Biol 29, 5813-27.

S. Teschner, P. Gerke, M. Geyer, J. Wilpert, B. Krumme, T. Benzing and G. Walz (2009) Leflunomide therapy for polyomavirus-induced allograft nephropathy: efficient BK virus elimination without increased risk of rejection Transplant Proc 41, 2533-8.

H. P. Neumann; C. Eng (2009) The approach to the patient with paraganglioma J Clin Endocrinol Metab 94, 2677-83.

Z. Erlic; H. P. Neumann (2009) Diagnosing patients with hereditary paraganglial tumours Lancet Oncol 10, 741.

T. Weide and T. B. Huber (2009) Signaling at the slit: podocytes chat by synaptic transmission J Am Soc Nephrol 20, 1862-4.

E. J. Benjamin, K. M. Rice, D. E. Arking, A. Pfeufer, C. van Noord, A. V. Smith, R. B. Schnabel, J. C. Bis, E. Boerwinkle, M. F. Sinner, A. Dehghan, S. A. Lubitz, R. B. D'Agostino, Sr., T. Lumley, G. B. Ehret, J. Heeringa, T. Aspelund, C. Newton-Cheh, M. G. Larson, K. D. Marciante, E. Z. Soliman, F. Rivadeneira, T. J. Wang, G. Eiriksdottir, D. Levy, B. M. Psaty, M. Li, A. M. Chamberlain, A. Hofman, R. S. Vasan, T. B. Harris, J. I. Rotter, W. H. Kao, S. K. Agarwal, B. H. Stricker, K. Wang, L. J. Launer, N. L. Smith, A. Chakravarti, A. G. Uitterlinden, P. A. Wolf, N. Sotoodehnia, A. Kottgen, C. M. van Duijn, T. Meitinger, M. Mueller, S. Perz, G. Steinbeck, H. E. Wichmann, K. L. Lunetta, S. R. Heckbert, V. Gudnason, A. Alonso, S. Kaab, P. T. Ellinor and J. C. Witteman (2009) Variants in ZFHX3 are associated with atrial fibrillation in individuals of European ancestry Nat Genet 41, 879-81.

R. Haribaskar, M. Putz, B. Schupp, K. Skouloudaki, A. Bietenbeck, G. Walz and T. Schafer (2009) The planar cell polarity (PCP) protein Diversin translocates to the nucleus to interact with the transcription factor AF9 Biochem Biophys Res Commun 387, 212-7.

J. Schipper; U. Spetzger; M. Tatagiba; S. Rosahl; H. P. Neumann; C. C. Boedeker; W. Maier (2009) Juxtacondylar approach in temporal paraganglioma surgery: when and why? Skull Base 19, 43-7.

C. C. Boedeker; H. P. Neumann; C. Offergeld; W. Maier; M. Falcioni; A. Berlis; J. Schipper (2009) Clinical features of paraganglioma syndromes Skull Base 19, 17-25.

E. Gkaliagkousi; Z. Erlic; K. Petidis; P. Semertzidis; M. Doumas; C. Zamboulis; H. P. Neumann; S. Douma (2009) Neurofibromatosis type 1: should we screen for other genetic syndromes? A case report of co-existence with multiple endocrine neoplasia 2A Eur J Clin Invest 39, 828-32.

M. Simons, B. Hartleben and T. B. Huber (2009) Podocyte polarity signalling Curr Opin Nephrol Hypertens 18, 324-30.

L. D. Bash, J. Coresh, A. Kottgen, R. S. Parekh, T. Fulop, Y. Wang and B. C. Astor (2009) Defining incident chronic kidney disease in the research setting: The ARIC Study Am J Epidemiol 170, 414-24.

O. M. Woodward, A. Kottgen, J. Coresh, E. Boerwinkle, W. B. Guggino and M. Kottgen (2009) Identification of a urate transporter, ABCG2, with a common functional polymorphism causing gout Proc Natl Acad Sci U S A 106, 10338-42.

E. Selvin, A. Kottgen and J. Coresh (2009) Kidney function estimated from serum creatinine and cystatin C and peripheral arterial disease in NHANES 1999-2002 Eur Heart J 30, 1918-25.

K. Skouloudaki, M. Puetz, M. Simons, J. R. Courbard, C. Boehlke, B. Hartleben, C. Engel, M. J. Moeller, C. Englert, F. Bollig, T. Schafer, H. Ramachandran, M. Mlodzik, T. B. Huber, E. W. Kuehn, E. Kim, A. Kramer-Zucker and G. Walz (2009) Scribble participates in Hippo signaling and is required for normal zebrafish pronephros development Proc Natl Acad Sci U S A 106, 8579-84.

A. Kottgen, N. L. Glazer, A. Dehghan, S. J. Hwang, R. Katz, M. Li, Q. Yang, V. Gudnason, L. J. Launer, T. B. Harris, A. V. Smith, D. E. Arking, B. C. Astor, E. Boerwinkle, G. B. Ehret, I. Ruczinski, R. B. Scharpf, Y. D. Chen, I. H. de Boer, T. Haritunians, T. Lumley, M. Sarnak, D. Siscovick, E. J. Benjamin, D. Levy, A. Upadhyay, Y. S. Aulchenko, A. Hofman, F. Rivadeneira, A. G. Uitterlinden, C. M. van Duijn, D. I. Chasman, G. Pare, P. M. Ridker, W. H. Kao, J. C. Witteman, J. Coresh, M. G. Shlipak and C. S. Fox (2009) Multiple loci associated with indices of renal function and chronic kidney disease Nat Genet 41, 712-7.

D. Levy, G. B. Ehret, K. Rice, G. C. Verwoert, L. J. Launer, A. Dehghan, N. L. Glazer, A. C. Morrison, A. D. Johnson, T. Aspelund, Y. Aulchenko, T. Lumley, A. Kottgen, R. S. Vasan, F. Rivadeneira, G. Eiriksdottir, X. Guo, D. E. Arking, G. F. Mitchell, F. U. Mattace-Raso, A. V. Smith, K. Taylor, R. B. Scharpf, S. J. Hwang, E. J. Sijbrands, J. Bis, T. B. Harris, S. K. Ganesh, C. J. O'Donnell, A. Hofman, J. I. Rotter, J. Coresh, E. J. Benjamin, A. G. Uitterlinden, G. Heiss, C. S. Fox, J. C. Witteman, E. Boerwinkle, T. J. Wang, V. Gudnason, M. G. Larson, A. Chakravarti, B. M. Psaty and C. M. van Duijn (2009) Genome-wide association study of blood pressure and hypertension Nat Genet 41, 677-87.

H. P. Neumann; Z. Erlic; C. C. Boedeker; L. A. Rybicki; M. Robledo; M. Hermsen; F. Schiavi; M. Falcioni; P. Kwok; C. Bauters; K. Lampe; M. Fischer; E. Edelman; D. E. Benn; B. G. Robinson; S. Wiegand; G. Rasp; B. A. Stuck; M. M. Hoffmann; M. Sullivan; M. A. Sevilla; M. M. Weiss; M. Peczkowska; A. Kubaszek; P. Pigny; R. L. Ward; D. Learoyd; M. Croxson; D. Zabolotny; S. Yaremchuk; W. Draf; M. Muresan; R. R. Lorenz; S. Knipping; M. Strohm; G. Dyckhoff; C. Matthias; N. Reisch; S. F. Preuss; D. Esser; M. A. Walter; H. Kaftan; T. Stover; C. Fottner; H. Gorgulla; M. Malekpour; M. M. Zarandy; J. Schipper; C. Brase; A. Glien; M. Kuhnemund; S. Koscielny; P. Schwerdtfeger; M. Valimaki; W. Szyfter; U. Finckh; K. Zerres; A. Cascon; G. Opocher; G. J. Ridder; A. Januszewicz; C. Suarez; C. Eng (2009) Clinical predictors for germline mutations in head and neck paraganglioma patients: cost reduction strategy in genetic diagnostic process as fall-out Cancer Res 69, 3650-6.

C. C. Boedeker; Z. Erlic; S. Richard; U. Kontny; A. P. Gimenez-Roqueplo; A. Cascon; M. Robledo; J. M. de Campos; F. H. van Nederveen; R. R. de Krijger; N. Burnichon; J. Gaal; M. A. Walter; K. Reschke; T. Wiech; J. Weber; K. Ruckauer; P. F. Plouin; V. Darrouzet; S. Giraud; C. Eng; H. P. Neumann (2009) Head and neck paragangliomas in von Hippel-Lindau disease and multiple endocrine neoplasia type 2 J Clin Endocrinol Metab 94, 1938-44.

H. Gao, L. K. Sellin, M. Putz, C. Nickel, M. Imgrund, P. Gerke, R. Nitschke, G. Walz and A. G. Kramer-Zucker (2009) A short carboxy-terminal domain of polycystin-1 reorganizes the microtubular network and the endoplasmic reticulum Exp Cell Res 315, 1157-70.

A. Pfeufer, S. Sanna, D. E. Arking, M. Muller, V. Gateva, C. Fuchsberger, G. B. Ehret, M. Orru, C. Pattaro, A. Kottgen, S. Perz, G. Usala, M. Barbalic, M. Li, B. Putz, A. Scuteri, R. J. Prineas, M. F. Sinner, C. Gieger, S. S. Najjar, W. H. Kao, T. W. Muhleisen, M. Dei, C. Happle, S. Mohlenkamp, L. Crisponi, R. Erbel, K. H. Jockel, S. Naitza, G. Steinbeck, F. Marroni, A. A. Hicks, E. Lakatta, B. Muller-Myhsok, P. P. Pramstaller, H. E. Wichmann, D. Schlessinger, E. Boerwinkle, T. Meitinger, M. Uda, J. Coresh, S. Kaab, G. R. Abecasis and A. Chakravarti (2009) Common variants at ten loci modulate the QT interval duration in the QTSCD Study Nat Genet 41, 407-14.

G. Franke; B. Bausch; M. M. Hoffmann; M. Cybulla; C. Wilhelm; J. Kohlhase; G. Scherer; H. P. Neumann (2009) Alu-Alu recombination underlies the vast majority of large VHL germline deletions: Molecular characterization and genotype-phenotype correlations in VHL patients Hum Mutat 30, 776-86.

T. B. Huber, B. Hartleben, K. Winkelmann, L. Schneider, J. U. Becker, M. Leitges, G. Walz, H. Haller and M. Schiffer (2009) Loss of podocyte aPKClambda/iota causes polarity defects and nephrotic syndrome J Am Soc Nephrol 20, 798-806.

R. Wobser, J. Wilpert, G. Kayser, G. Walz and M. Stubanus (2009) [Disseminated histoplasmosis with involvement of mediastinum and skin in an immunocompetent patient] Dtsch Med Wochenschr 134, 589-93.

Z. Erlic; H. P. Neumann (2009) Familial pheochromocytoma Hormones (Athens) 8, 29-38.

B. Rumberger, C. Kreutz, C. Nickel, M. Klein, S. Lagoutte, S. Teschner, J. Timmer, P. Gerke, G. Walz and J. Donauer (2009) Combination of immunosuppressive drugs leaves specific "fingerprint" on gene expression in vitro Immunopharmacol Immunotoxicol 31, 283-92.

M. Simons; W. J. Gault; D. Gotthardt; R. Rohatgi; T. J. Klein; Y. Shao; H. J. Lee; A. L. Wu; Y. Fang; L. M. Satlin; J. T. Dow; J. Chen; J. Zheng; M. Boutros; M. Mlodzik (2009) Electrochemical cues regulate assembly of the Frizzled/Dishevelled complex at the plasma membrane during planar epithelial polarization Nat Cell Biol 11, 286-94.

M. Simons and T. B. Huber (2009) Flying podocytes Kidney Int 75, 455-7.

T. Wegierski, D. Steffl, C. Kopp, R. Tauber, B. Buchholz, R. Nitschke, E. W. Kuehn, G. Walz and M. Kottgen (2009) TRPP2 channels regulate apoptosis through the Ca2+ concentration in the endoplasmic reticulum EMBO J 28, 490-9.

S. J. Arnold and E. J. Robertson (2009) Making a commitment: cell lineage allocation and axis patterning in the early mouse embryo Nat Rev Mol Cell Biol 10, 91-103.

W. Reichardt, D. Romaker, A. Becker, M. Buechert, G. Walz and D. von Elverfeldt (2009) Monitoring kidney and renal cyst volumes applying MR approaches on a rapamycin treated mouse model of ADPKD MAGMA 22, 143-9.

N. Reisch; M. K. Walz; Z. Erlic; H. P. Neumann (2009) [Pheochromocytoma - still a challenge] Internist (Berl) 50, 27-35.

Z. Erlic; H. P. Neumann (2009) When should genetic testing be obtained in a patient with phaeochromocytoma or paraganglioma? Clin Endocrinol (Oxf) 70, 354-7.

T. Wegierski, U. Lewandrowski, B. Muller, A. Sickmann and G. Walz (2009) Tyrosine phosphorylation modulates the activity of TRPV4 in response to defined stimuli J Biol Chem 284, 2923-33.

M. Geyer, K. G. Fischer, O. Drognitz, G. Walz, P. Pisarski and J. Wilpert (2009) ABO-incompatible kidney transplantation with antigen-specific immunoadsorption and rituximab - insights and uncertainties Contrib Nephrol 162, 47-60.

D. Romaker, M. Puetz, S. Teschner, J. Donauer, M. Geyer, P. Gerke, B. Rumberger, B. Dworniczak, P. Pennekamp, B. Buchholz, H. P. Neumann, R. Kumar, J. Gloy, K. U. Eckardt and G. Walz (2009) Increased expression of secreted frizzled-related protein 4 in polycystic kidneys J Am Soc Nephrol 20, 48-56.

Y. Yan, K. E. North, C. M. Ballantyne, F. L. Brancati, L. E. Chambless, N. Franceschini, G. Heiss, A. Kottgen, J. S. Pankow, E. Selvin, S. L. West and E. Boerwinkle (2009) Transcription factor 7-like 2 (TCF7L2) polymorphism and context-specific risk of type 2 diabetes in African American and Caucasian adults: the Atherosclerosis Risk in Communities study Diabetes 58, 285-9.

A. Dehghan, A. Kottgen, Q. Yang, S. J. Hwang, W. L. Kao, F. Rivadeneira, E. Boerwinkle, D. Levy, A. Hofman, B. C. Astor, E. J. Benjamin, C. M. van Duijn, J. C. Witteman, J. Coresh and C. S. Fox (2008) Association of three genetic loci with uric acid concentration and risk of gout: a genome-wide association study Lancet 372, 1953-61.

E. Neumann-Haefelin, W. Qi, E. Finkbeiner, G. Walz, R. Baumeister and M. Hertweck (2008) SHC-1/p52Shc targets the insulin/IGF-1 and JNK signaling pathways to modulate life span and stress response in C. elegans Genes Dev 22, 2721-35.

A. Pazin-Filho, A. Kottgen, A. G. Bertoni, S. D. Russell, E. Selvin, W. D. Rosamond and J. Coresh (2008) HbA 1c as a risk factor for heart failure in persons with diabetes: the Atherosclerosis Risk in Communities (ARIC) study Diabetologia 51, 2197-204.

M. Peczkowska; Z. Erlic; M. M. Hoffmann; M. Furmanek; J. Cwikla; A. Kubaszek; A. Prejbisz; Z. Szutkowski; A. Kawecki; K. Chojnowski; A. Lewczuk; M. Litwin; W. Szyfter; M. A. Walter; M. Sullivan; C. Eng; A. Januszewicz; H. P. Neumann (2008) Impact of screening kindreds for SDHD p.Cys11X as a common mutation associated with paraganglioma syndrome type 1 J Clin Endocrinol Metab 93, 4818-25.

D. Groesbeck, A. Kottgen, R. Parekh, E. Selvin, G. J. Schwartz, J. Coresh and S. Furth (2008) Age, gender, and race effects on cystatin C levels in US adolescents Clin J Am Soc Nephrol 3, 1777-85.

B. Hoffmann; M. Beck; A. Rolfs; H. P. Neumann (2008) [Fabry disease - complex clinical picture, simple diagnosis procedure, causal treatment] Dtsch Med Wochenschr 133, 1965-72; quiz 1973-4.

S. J. Arnold, G. J. Huang, A. F. Cheung, T. Era, S. Nishikawa, E. K. Bikoff, Z. Molnar, E. J. Robertson and M. Groszer (2008) The T-box transcription factor Eomes/Tbr2 regulates neurogenesis in the cortical subventricular zone Genes Dev 22, 2479-84.

I. N. Milos; K. Frank-Raue; N. Wohllk; A. L. Maia; E. Pusiol; A. Patocs; M. Robledo; J. Biarnes; M. Barontini; T. P. Links; J. W. de Groot; S. Dvorakova; M. Peczkowska; L. A. Rybicki; M. Sullivan; F. Raue; I. Zosin; C. Eng; H. P. Neumann (2008) Age-related neoplastic risk profiles and penetrance estimations in multiple endocrine neoplasia type 2A caused by germ line RET Cys634Trp (TGC>TGG) mutation Endocr Relat Cancer 15, 1035-41.

T. Schafer, M. Putz, S. Lienkamp, A. Ganner, A. Bergbreiter, H. Ramachandran, V. Gieloff, M. Gerner, C. Mattonet, P. G. Czarnecki, J. A. Sayer, E. A. Otto, F. Hildebrandt, A. Kramer-Zucker and G. Walz (2008) Genetic and physical interaction between the NPHP5 and NPHP6 gene products Hum Mol Genet 17, 3655-62.

M. Simons; M. Mlodzik (2008) Planar cell polarity signaling: from fly development to human disease Annu Rev Genet 42, 517-40.

M. Kottgen, B. Buchholz, M. A. Garcia-Gonzalez, F. Kotsis, X. Fu, M. Doerken, C. Boehlke, D. Steffl, R. Tauber, T. Wegierski, R. Nitschke, M. Suzuki, A. Kramer-Zucker, G. G. Germino, T. Watnick, J. Prenen, B. Nilius, E. W. Kuehn and G. Walz (2008) TRPP2 and TRPV4 form a polymodal sensory channel complex J Cell Biol 182, 437-47.

A. Kottgen, S. J. Hwang, E. Rampersaud, J. Coresh, K. E. North, J. S. Pankow, J. B. Meigs, J. C. Florez, A. Parsa, D. Levy, E. Boerwinkle, A. R. Shuldiner, C. S. Fox and W. H. Kao (2008) TCF7L2 variants associate with CKD progression and renal function in population-based cohorts J Am Soc Nephrol 19, 1989-99.

K. Duning, E. M. Schurek, M. Schluter, M. Bayer, H. C. Reinhardt, A. Schwab, L. Schaefer, T. Benzing, B. Schermer, M. A. Saleem, T. B. Huber, S. Bachmann, J. Kremerskothen, T. Weide and H. Pavenstadt (2008) KIBRA modulates directional migration of podocytes J Am Soc Nephrol 19, 1891-903.

B. Hartleben, H. Schweizer, P. Lubben, M. P. Bartram, C. C. Moller, R. Herr, C. Wei, E. Neumann-Haefelin, B. Schermer, H. Zentgraf, D. Kerjaschki, J. Reiser, G. Walz, T. Benzing and T. B. Huber (2008) Neph-Nephrin proteins bind the Par3-Par6-atypical protein kinase C (aPKC) complex to regulate podocyte cell polarity J Biol Chem 283, 23033-8.

A. Kottgen, W. H. Kao, S. J. Hwang, E. Boerwinkle, Q. Yang, D. Levy, E. J. Benjamin, M. G. Larson, B. C. Astor, J. Coresh and C. S. Fox (2008) Genome-wide association study for renal traits in the Framingham Heart and Atherosclerosis Risk in Communities Studies BMC Med Genet 9, 49.

D. Szumska, G. Pieles, R. Essalmani, M. Bilski, D. Mesnard, K. Kaur, A. Franklyn, K. El Omari, J. Jefferis, J. Bentham, J. M. Taylor, J. E. Schneider, S. J. Arnold, P. Johnson, Z. Tymowska-Lalanne, D. Stammers, K. Clarke, S. Neubauer, A. Morris, S. D. Brown, C. Shaw-Smith, A. Cama, V. Capra, J. Ragoussis, D. Constam, N. G. Seidah, A. Prat and S. Bhattacharya (2008) VACTERL/caudal regression/Currarino syndrome-like malformations in mice with mutation in the proprotein convertase Pcsk5 Genes Dev 22, 1465-77.

C. D. Margetts; M. Morris; D. Astuti; D. C. Gentle; A. Cascon; F. E. McRonald; D. Catchpoole; M. Robledo; H. P. Neumann; F. Latif; E. R. Maher (2008) Evaluation of a functional epigenetic approach to identify promoter region methylation in phaeochromocytoma and neuroblastoma Endocr Relat Cancer 15, 777-86.

A. Kottgen, C. C. Hsu, J. Coresh, A. R. Shuldiner, Y. Berthier-Schaad, T. R. Gambhir, M. W. Smith, E. Boerwinkle and W. H. Kao (2008) The association of podocin R229Q polymorphism with increased albuminuria or reduced estimated GFR in a large population-based sample of US adults Am J Kidney Dis 52, 868-75.

Y. Luke, H. Zaim, I. Karakesisoglou, V. M. Jaeger, L. Sellin, W. Lu, M. Schneider, S. Neumann, A. Beijer, M. Munck, V. C. Padmakumar, J. Gloy, G. Walz and A. A. Noegel (2008) Nesprin-2 Giant (NUANCE) maintains nuclear envelope architecture and composition in skin J Cell Sci 121, 1887-98.

H. P. Neumann; Z. Erlic (2008) Maternal transmission of symptomatic disease with SDHD mutation: fact or fiction? J Clin Endocrinol Metab 93, 1573-5.

T. B. Huber (2008) [Molecular pathogenesis of proteinuria] Dtsch Med Wochenschr 133, 954-8.

F. Kotsis, R. Nitschke, M. Doerken, G. Walz and E. W. Kuehn (2008) Flow modulates centriole movements in tubular epithelial cells Pflugers Arch 456, 1025-35.

X. Fu, Y. Wang, N. Schetle, H. Gao, M. Putz, G. von Gersdorff, G. Walz and A. G. Kramer-Zucker (2008) The subcellular localization of TRPP2 modulates its function J Am Soc Nephrol 19, 1342-51.

C. Bergmann, M. Fliegauf, N. O. Bruchle, V. Frank, H. Olbrich, J. Kirschner, B. Schermer, I. Schmedding, A. Kispert, B. Kranzlin, G. Nurnberg, C. Becker, T. Grimm, G. Girschick, S. A. Lynch, P. Kelehan, J. Senderek, T. J. Neuhaus, T. Stallmach, H. Zentgraf, P. Nurnberg, N. Gretz, C. Lo, S. Lienkamp, T. Schafer, G. Walz, T. Benzing, K. Zerres and H. Omran (2008) Loss of nephrocystin-3 function can cause embryonic lethality, Meckel-Gruber-like syndrome, situs inversus, and renal-hepatic-pancreatic dysplasia Am J Hum Genet 82, 959-70.

M. Simons and T. B. Huber (2008) It's not all about nephrin Kidney Int 73, 671-3.

A. Kottgen, E. Selvin, L. A. Stevens, A. S. Levey, F. Van Lente and J. Coresh (2008) Serum cystatin C in the United States: the Third National Health and Nutrition Examination Survey (NHANES III) Am J Kidney Dis 51, 385-94.

M. Peczkowska; A. Cascon; A. Prejbisz; A. Kubaszek; B. J. Cwikla; M. Furmanek; Z. Erlic; C. Eng; A. Januszewicz; H. P. Neumann (2008) Extra-adrenal and adrenal pheochromocytomas associated with a germline SDHC mutation Nat Clin Pract Endocrinol Metab 4, 111-5.

S. Akilesh, T. B. Huber, H. Wu, G. Wang, B. Hartleben, J. B. Kopp, J. H. Miner, D. C. Roopenian, E. R. Unanue and A. S. Shaw (2008) Podocytes use FcRn to clear IgG from the glomerular basement membrane Proc Natl Acad Sci U S A 105, 967-72.

S. J. Arnold, U. K. Hofmann, E. K. Bikoff and E. J. Robertson (2008) Pivotal roles for eomesodermin during axis formation, epithelium-to-mesenchyme transition and endoderm specification in the mouse Development 135, 501-11.

A. Cascon; I. Landa; E. Lopez-Jimenez; A. Diez-Hernandez; M. Buchta; C. Montero-Conde; S. Leskela; L. J. Leandro-Garcia; R. Leton; C. Rodriguez-Antona; C. Eng; H. P. Neumann; M. Robledo (2008) Molecular characterisation of a common SDHB deletion in paraganglioma patients J Med Genet 45, 233-8.

V. Frank, A. I. den Hollander, N. O. Bruchle, M. N. Zonneveld, G. Nurnberg, C. Becker, G. Du Bois, H. Kendziorra, S. Roosing, J. Senderek, P. Nurnberg, F. P. Cremers, K. Zerres and C. Bergmann (2008) Mutations of the CEP290 gene encoding a centrosomal protein cause Meckel-Gruber syndrome Hum Mutat 29, 45-52.

E. W. Kuehn, M. N. Hirt, A. K. John, P. Muehlenhardt, C. Boehlke, M. Putz, A. G. Kramer-Zucker, M. Bashkurov, P. S. van de Weyer, F. Kotsis and G. Walz (2007) Kidney injury molecule 1 (Kim1) is a novel ciliary molecule and interactor of polycystin 2 Biochem Biophys Res Commun 364, 861-6.

M. Geyer, J. Donauer, P. Pisarski, O. Drognitz, C. Schulz-Huotari, U. Wisniewski, A. Gropp, H. Gobel, P. Gerke, S. Teschner, G. Walz and J. Wilpert (2007) Preemptive postoperative antigen-specific immunoadsorption in ABO-incompatible kidney transplantation: necessary or not? Transplantation 84, S40-3.

J. Wilpert, M. Geyer, S. Teschner, T. Schaefer, P. Pisarski, C. Schulz-Huotari, A. Gropp, U. Wisniewski, H. Goebel, P. Gerke, G. Walz and J. Donauer (2007) ABO-incompatible kidney transplantation-proposal of an intensified apheresis strategy for patients with high initial isoagglutinine titers J Clin Apher 22, 314-22.

E. Kim and G. Walz (2007) Sensitive cilia set up the kidney Nat Med 13, 1409-11.

E. J. Robertson, I. Charatsi, C. J. Joyner, C. H. Koonce, M. Morgan, A. Islam, C. Paterson, E. Lejsek, S. J. Arnold, A. Kallies, S. L. Nutt and E. K. Bikoff (2007) Blimp1 regulates development of the posterior forelimb, caudal pharyngeal arches, heart and sensory vibrissae in mice Development 134, 4335-45.

U. T. Schultheiss, H. Gobel, G. von Gersdorff, M. Stubanus, G. Walz and P. Gerke (2007) Quiz page December 2007: diarrhea and anuria in a recipient of an en bloc infant kidney transplant Am J Kidney Dis 50, A41-3.

S. Clorius, K. Technau, T. Watter, E. Schwertfeger, K. G. Fischer, G. Walz and P. Gerke (2007) Nephrogenic systemic fibrosis following exposure to gadolinium-containing contrast agent Clin Nephrol 68, 249-52.

M. Cybulla; H. P. Neumann (2007) [Fabry disease. An interdisciplinary challenge] Dtsch Med Wochenschr 132, 2271-7.

Y. Wang, X. Fu, S. Gaiser, M. Kottgen, A. Kramer-Zucker, G. Walz and T. Wegierski (2007) OS-9 regulates the transit and polyubiquitination of TRPV4 in the endoplasmic reticulum J Biol Chem 282, 36561-70.

H. P. Neumann; A. Vortmeyer; D. Schmidt; M. Werner; Z. Erlic; A. Cascon; B. Bausch; A. Januszewicz; C. Eng (2007) Evidence of MEN-2 in the original description of classic pheochromocytoma N Engl J Med 357, 1311-5.

B. Rumberger, O. Vonend, C. Kreutz, J. Wilpert, J. Donauer, K. Amann, R. Rohrbach, J. Timmer, G. Walz and P. Gerke (2007) cDNA microarray analysis of adaptive changes after renal ablation in a sclerosis-resistant mouse strain Kidney Blood Press Res 30, 377-87.

A. Ganner, Y. M. Lee, C. Busche, A. Schmitt-Graeff, J. Encke, G. Walz and P. Gerke (2007) Successful liver transplantation in a kidney and pancreas allograft recipient with fulminant herpes simplex virus type 2 hepatitis Nephrol Dial Transplant 22, 3334-7.

D. Steffl, H. Gobel, C. Groth, K. G. Fischer, W. Kuhn, G. Walz and P. Gerke (2007) Quiz page. Renal AA amyloidosis with vascular predominance, secondary to rheumatoid arthritis Am J Kidney Dis 49, A49-50.

M. Stubanus, H. Gobel, S. Rieg, G. Walz and P. Gerke (2007) Quiz page. Minimal change glomerulonephritis associated with secondary syphilis Am J Kidney Dis 49, A49-50.

J. Wilpert, M. Geyer, P. Pisarski, O. Drognitz, C. Schulz-Huotari, A. Gropp, H. Goebel, P. Gerke, S. Teschner, G. Walz and J. Donauer (2007) On-demand strategy as an alternative to conventionally scheduled post-transplant immunoadsorptions after ABO-incompatible kidney transplantation Nephrol Dial Transplant 22, 3048-51.

J. M. Langrehr; M. Bahra; G. Kristiansen; H. P. Neumann; L. M. Neumann; U. Plockinger; E. Lopez-Hanninen (2007) Neuroendocrine tumor of the pancreas and bilateral adrenal pheochromocytomas. A rare manifestation of von Hippel-Lindau disease in childhood J Pediatr Surg 42, 1291-4.

M. Cybulla; K. Walter; H. P. Neumann; U. Widmer; M. Scharer; G. Sunder-Plassmann; T. Jansen; A. Rolfs; M. Beck (2007) [Fabry disease: demographic data since introduction of enzyme replacement therapy] Dtsch Med Wochenschr 132, 1505-9.

C. Bergmann and K. Zerres (2007) Early manifestations of polycystic kidney disease Lancet 369, 2157.

C. C. Boedeker; H. P. Neumann; W. Maier; B. Bausch; J. Schipper; G. J. Ridder (2007) Malignant head and neck paragangliomas in SDHB mutation carriers Otolaryngol Head Neck Surg 137, 126-9.

T. B. Huber, B. Schermer and T. Benzing (2007) Podocin organizes ion channel-lipid supercomplexes: implications for mechanosensation at the slit diaphragm Nephron Exp Nephrol 106, e27-31.

E. W. Kuehn, G. Walz and T. Benzing (2007) Von hippel-lindau: a tumor suppressor links microtubules to ciliogenesis and cancer development Cancer Res 67, 4537-40.

B. U. Bender; T. Quaschning; H. P. Neumann; D. Schmidt; A. Kraemer-Guth (2007) A novel frameshift mutation of the lecithin:cholesterol acyltransferase (LCAT) gene associated with renal failure in familial LCAT deficiency Clin Chem Lab Med 45, 483-6.

V. Frank, N. Ortiz Bruchle, S. Mager, S. G. Frints, A. Bohring, G. du Bois, I. Debatin, H. Seidel, J. Senderek, N. Besbas, U. Todt, C. Kubisch, T. Grimm, F. Teksen, S. Balci, K. Zerres and C. Bergmann (2007) Aberrant splicing is a common mutational mechanism in MKS1, a key player in Meckel-Gruber syndrome Hum Mutat 28, 638-9.

T. Benzing, M. Simons and G. Walz (2007) Wnt signaling in polycystic kidney disease J Am Soc Nephrol 18, 1389-98.

B. Bausch; W. Borozdin; V. F. Mautner; M. M. Hoffmann; D. Boehm; M. Robledo; A. Cascon; T. Harenberg; F. Schiavi; C. Pawlu; M. Peczkowska; C. Letizia; S. Calvieri; G. Arnaldi; R. D. Klingenberg-Noftz; N. Reisch; A. Fassina; L. Brunaud; M. A. Walter; M. Mannelli; G. MacGregor; F. F. Palazzo; M. Barontini; M. K. Walz; B. Kremens; G. Brabant; R. Pfaffle; A. C. Koschker; F. Lohoefner; M. Mohaupt; O. Gimm; B. Jarzab; S. R. McWhinney; G. Opocher; A. Januszewicz; J. Kohlhase; C. Eng; H. P. Neumann (2007) Germline NF1 mutational spectra and loss-of-heterozygosity analyses in patients with pheochromocytoma and neurofibromatosis type 1 J Clin Endocrinol Metab 92, 2784-92.

S. C. Bhakdi; P. Sratongno; P. Chimma; T. Rungruang; A. Chuncharunee; H. P. Neumann; P. Malasit; K. Pattanapanyasat (2007) Re-evaluating acridine orange for rapid flow cytometric enumeration of parasitemia in malaria-infected rodents Cytometry A 71, 662-7.

E. W. Kuehn and G. Walz (2007) Prime time for polycystic kidney disease: does one shot of roscovitine bring the cure? Nephrol Dial Transplant 22, 2133-5.

K. M. Kreusel; N. E. Bechrakis; H. P. Neumann; D. Schmidt; M. H. Foerster (2007) Solitary juxtapapillary capillary retinal angioma and von Hippel-Lindau disease Can J Ophthalmol 42, 251-5.

A. Kottgen, S. D. Russell, L. R. Loehr, C. M. Crainiceanu, W. D. Rosamond, P. P. Chang, L. E. Chambless and J. Coresh (2007) Reduced kidney function as a risk factor for incident heart failure: the atherosclerosis risk in communities (ARIC) study J Am Soc Nephrol 18, 1307-15.

Y. Liu, N. Pathak, A. Kramer-Zucker and I. A. Drummond (2007) Notch signaling controls the differentiation of transporting epithelia and multiciliated cells in the zebrafish pronephros Development 134, 1111-22.

H. P. Neumann; M. Cybulla; S. Glasker; C. Coulin; V. Van Velthoven; A. Berlis; C. Hader; O. Schafer; M. Treier; I. Brink; W. Schultze-Seemann; C. Leiber; K. Ruckauer; B. Junker; F. J. Agostini; A. Hetzel; C. C. Boedeker (2007) [Von Hippel-Lindau disease. Interdisciplinary patient care] Ophthalmologe 104, 119-26.

F. Kotsis, R. Nitschke, C. Boehlke, M. Bashkurov, G. Walz and E. W. Kuehn (2007) Ciliary calcium signaling is modulated by kidney injury molecule-1 (Kim1) Pflugers Arch 453, 819-29.

D. Boehm; J. Bacher; H. P. Neumann (2007) Gross genomic rearrangement involving the TSC2-PKD1 contiguous deletion syndrome: characterization of the deletion event by quantitative polymerase chain reaction deletion assay Am J Kidney Dis 49, e11-21.

K. M. Kreusel; N. E. Bechrakis; H. P. Neumann; M. H. Foerster (2007) [Juxtapapillary capillary retinal angioma with epiretinal membrane of the macula in familial Von-Hippel-Lindau-Syndrome] Ophthalmologe 104, 317-20.

a. W. G. Kühn W (2007) Autosomal Dominante Polyzystische Nierenerkrankung Deutsches Ärzteblatt 104, A-3022-3028.

M. K. Walz; P. F. Alesina; F. A. Wenger; A. Deligiannis; E. Szuczik; S. Petersenn; A. Ommer; H. Groeben; K. Peitgen; O. E. Janssen; T. Philipp; H. P. Neumann; K. W. Schmid; K. Mann (2006) Posterior retroperitoneoscopic adrenalectomy--results of 560 procedures in 520 patients Surgery 140, 943-8; discussion 948-50.

U. Klingmuller, A. Bauer, S. Bohl, P. J. Nickel, K. Breitkopf, S. Dooley, S. Zellmer, C. Kern, I. Merfort, T. Sparna, J. Donauer, G. Walz, M. Geyer, C. Kreutz, M. Hermes, F. Gotschel, A. Hecht, D. Walter, L. Egger, K. Neubert, C. Borner, M. Brulport, W. Schormann, C. Sauer, F. Baumann, R. Preiss, S. MacNelly, P. Godoy, E. Wiercinska, L. Ciuclan, J. Edelmann, K. Zeilinger, M. Heinrich, U. M. Zanger, R. Gebhardt, T. Maiwald, R. Heinrich, J. Timmer, F. von Weizsacker and J. G. Hengstler (2006) Primary mouse hepatocytes for systems biology approaches: a standardized in vitro system for modelling of signal transduction pathways Syst Biol (Stevenage) 153, 433-47.

T. Wegierski, K. Hill, M. Schaefer and G. Walz (2006) The HECT ubiquitin ligase AIP4 regulates the cell surface expression of select TRP channels EMBO J 25, 5659-69.

B. Bausch; C. C. Boedeker; A. Berlis; I. Brink; M. Cybulla; M. K. Walz; A. Januszewicz; C. Letizia; G. Opocher; C. Eng; H. P. Neumann (2006) Genetic and clinical investigation of pheochromocytoma: a 22-year experience, from Freiburg, Germany to international effort Ann N Y Acad Sci 1073, 122-37.

B. Schermer, C. Ghenoiu, M. Bartram, R. U. Muller, F. Kotsis, M. Hohne, W. Kuhn, M. Rapka, R. Nitschke, H. Zentgraf, M. Fliegauf, H. Omran, G. Walz and T. Benzing (2006) The von Hippel-Lindau tumor suppressor protein controls ciliogenesis by orienting microtubule growth J Cell Biol 175, 547-54.

N. Reisch; M. Peczkowska; A. Januszewicz; H. P. Neumann (2006) Pheochromocytoma: presentation, diagnosis and treatment J Hypertens 24, 2331-9.

T. B. Huber, B. Schermer, R. U. Muller, M. Hohne, M. Bartram, A. Calixto, H. Hagmann, C. Reinhardt, F. Koos, K. Kunzelmann, E. Shirokova, D. Krautwurst, C. Harteneck, M. Simons, H. Pavenstadt, D. Kerjaschki, C. Thiele, G. Walz, M. Chalfie and T. Benzing (2006) Podocin and MEC-2 bind cholesterol to regulate the activity of associated ion channels Proc Natl Acad Sci U S A 103, 17079-86.

P. S. van de Weyer, M. Muehlfeit, C. Klose, J. V. Bonventre, G. Walz and E. W. Kuehn (2006) A highly conserved tyrosine of Tim-3 is phosphorylated upon stimulation by its ligand galectin-9 Biochem Biophys Res Commun 351, 571-6.

M. Simons (2006) Nephrologists sans frontieres: On the metamorphosis of turning into a fly geneticist Kidney Int 70, 1387-8.

T. Obara, S. Mangos, Y. Liu, J. Zhao, S. Wiessner, A. G. Kramer-Zucker, F. Olale, A. F. Schier and I. A. Drummond (2006) Polycystin-2 immunolocalization and function in zebrafish J Am Soc Nephrol 17, 2706-18.

M. Cybulla; M. Kleber; K. N. Walter; S. M. Kroeber; H. P. Neumann; M. Engelhardt (2006) Is Fabry disease associated with leukaemia? Br J Haematol 135, 264-5.

R. Baumeister, E. Schaffitzel and M. Hertweck (2006) Endocrine signaling in Caenorhabditis elegans controls stress response and longevity J Endocrinol 190, 191-202.

C. Bergmann, V. Frank, F. Kupper, C. Schmidt, J. Senderek and K. Zerres (2006) Functional analysis of PKHD1 splicing in autosomal recessive polycystic kidney disease J Hum Genet 51, 788-93.

M. Fliegauf; J. Horvath; C. von Schnakenburg; H. Olbrich; D. Muller; J. Thumfart; B. Schermer; G. J. Pazour; H. P. Neumann; H. Zentgraf; T. Benzing; H. Omran (2006) Nephrocystin specifically localizes to the transition zone of renal and respiratory cilia and photoreceptor connecting cilia J Am Soc Nephrol 17, 2424-33.

A. M. Muller; A. Geibel; H. P. Neumann; A. Kuhnemund; A. Schmitt-Graff; J. Bohm; M. Engelhardt (2006) Primary (AL) amyloidosis in plasma cell disorders Oncologist 11, 824-30.

P. Gerke, T. Benzing, M. Hohne, A. Kispert, M. Frotscher, G. Walz and O. Kretz (2006) Neuronal expression and interaction with the synaptic protein CASK suggest a role for Neph1 and Neph2 in synaptogenesis J Comp Neurol 498, 466-75.

M. Simons and G. Walz (2006) Polycystic kidney disease: cell division without a c(l)ue? Kidney Int 70, 854-64.

B. Bausch; W. Borozdin; H. P. Neumann (2006) Clinical and genetic characteristics of patients with neurofibromatosis type 1 and pheochromocytoma N Engl J Med 354, 2729-31.

B. Bausch; A. C. Koschker; M. Fassnacht; J. Stoevesandt; M. M. Hoffmann; C. Eng; B. Allolio; H. P. Neumann (2006) Comprehensive mutation scanning of NF1 in apparently sporadic cases of pheochromocytoma J Clin Endocrinol Metab 91, 3478-81.

K. M. Kreusel; N. E. Bechrakis; L. Krause; H. P. Neumann; M. H. Foerster (2006) Retinal angiomatosis in von Hippel-Lindau disease: a longitudinal ophthalmologic study Ophthalmology 113, 1418-24.

S. J. Arnold, S. Maretto, A. Islam, E. K. Bikoff and E. J. Robertson (2006) Dose-dependent Smad1, Smad5 and Smad8 signaling in the early mouse embryo Dev Biol 296, 104-18.

X. Fang, M. B. Zeisel, J. Wilpert, B. Gissler, R. Thimme, C. Kreutz, T. Maiwald, J. Timmer, W. V. Kern, J. Donauer, M. Geyer, G. Walz, E. Depla, F. von Weizsacker, H. E. Blum and T. F. Baumert (2006) Host cell responses induced by hepatitis C virus binding Hepatology 43, 1326-36.

A. Nebel, E. Schaffitzel and M. Hertweck (2006) Aging at the interface of stem cell renewal, apoptosis, senescence, and cancer Sci Aging Knowledge Environ 2006, pe14.

S. Bruck, T. B. Huber, R. J. Ingham, K. Kim, H. Niederstrasser, P. M. Allen, T. Pawson, J. A. Cooper and A. S. Shaw (2006) Identification of a novel inhibitory actin-capping protein binding motif in CD2-associated protein J Biol Chem 281, 19196-203.

C. A. Koch; F. M. Brouwers; A. O. Vortmeyer; A. Tannapfel; S. K. Libutti; Z. Zhuang; K. Pacak; H. P. Neumann; R. Paschke (2006) Somatic VHL gene alterations in MEN2-associated medullary thyroid carcinoma BMC Cancer 6, 131.

G. Walz (2006) Therapeutic approaches in autosomal dominant polycystic kidney disease (ADPKD): is there light at the end of the tunnel? Nephrol Dial Transplant 21, 1752-7.

C. Fuentes; E. Menendez; J. Pineda; J. P. Martinez De Esteban; E. Anda; M. J. Goni; B. Bausch; H. P. Neumann (2006) The malignant potential of a succinate dehydrogenase subunit B germline mutation J Endocrinol Invest 29, 350-2.

J. A. Sayer, E. A. Otto, J. F. O'Toole, G. Nurnberg, M. A. Kennedy, C. Becker, H. C. Hennies, J. Helou, M. Attanasio, B. V. Fausett, B. Utsch, H. Khanna, Y. Liu, I. Drummond, I. Kawakami, T. Kusakabe, M. Tsuda, L. Ma, H. Lee, R. G. Larson, S. J. Allen, C. J. Wilkinson, E. A. Nigg, C. Shou, C. Lillo, D. S. Williams, B. Hoppe, M. J. Kemper, T. Neuhaus, M. A. Parisi, I. A. Glass, M. Petry, A. Kispert, J. Gloy, A. Ganner, G. Walz, X. Zhu, D. Goldman, P. Nurnberg, A. Swaroop, M. R. Leroux and F. Hildebrandt (2006) The centrosomal protein nephrocystin-6 is mutated in Joubert syndrome and activates transcription factor ATF4 Nat Genet 38, 674-81.

M. Prelog, C. Bergmann, M. J. Ausserlechner, H. Fischer, R. Margreiter, I. Gassner, A. Brunner, T. C. Jungraithmayr, K. Zerres, C. Sergi and L. B. Zimmerhackl (2006) Successful transplantation in a child with rapid progression of autosomal recessive polycystic kidney disease associated with a novel mutation Pediatr Transplant 10, 362-6.

S. Teschner, M. Geyer, J. Wilpert, E. Schwertfeger, T. Schenk, G. Walz and J. Donauer (2006) Remission of polyomavirus-induced graft nephropathy treated with low-dose leflunomide Nephrol Dial Transplant 21, 2039-40.

E. Ellertsdottir, J. Ganz, K. Durr, N. Loges, F. Biemar, F. Seifert, A. K. Ettl, A. K. Kramer-Zucker, R. Nitschke and W. Driever (2006) A mutation in the zebrafish Na,K-ATPase subunit atp1a1a.1 provides genetic evidence that the sodium potassium pump contributes to left-right asymmetry downstream or in parallel to nodal flow Dev Dyn 235, 1794-808.

T. B. Huber, C. Kwoh, H. Wu, K. Asanuma, M. Godel, B. Hartleben, K. J. Blumer, J. H. Miner, P. Mundel and A. S. Shaw (2006) Bigenic mouse models of focal segmental glomerulosclerosis involving pairwise interaction of CD2AP, Fyn, and synaptopodin J Clin Invest 116, 1337-45.

J. Donauer, J. Wilpert, M. Geyer, E. Schwertfeger, G. Kirste, O. Drognitz, G. Walz and P. Pisarski (2006) ABO-incompatible kidney transplantation using antigen-specific immunoadsorption and rituximab: a single center experience Xenotransplantation 13, 108-10.

M. K. Walz; P. F. Alesina; F. A. Wenger; J. A. Koch; H. P. Neumann; S. Petersenn; K. W. Schmid; K. Mann (2006) Laparoscopic and retroperitoneoscopic treatment of pheochromocytomas and retroperitoneal paragangliomas: results of 161 tumors in 126 patients World J Surg 30, 899-908.

T. Benzing and G. Walz (2006) Cilium-generated signaling: a cellular GPS? Curr Opin Nephrol Hypertens 15, 245-9.

E. Schaffitzel and M. Hertweck (2006) Recent aging research in Caenorhabditis elegans Exp Gerontol 41, 557-63.

J. M. Shillingford, N. S. Murcia, C. H. Larson, S. H. Low, R. Hedgepeth, N. Brown, C. A. Flask, A. C. Novick, D. A. Goldfarb, A. Kramer-Zucker, G. Walz, K. B. Piontek, G. G. Germino and T. Weimbs (2006) The mTOR pathway is regulated by polycystin-1, and its inhibition reverses renal cystogenesis in polycystic kidney disease Proc Natl Acad Sci U S A 103, 5466-71.

G. Schieren, B. Rumberger, M. Klein, C. Kreutz, J. Wilpert, M. Geyer, D. Faller, J. Timmer, I. Quack, L. C. Rump, G. Walz and J. Donauer (2006) Gene profiling of polycystic kidneys Nephrol Dial Transplant 21, 1816-24.

K. M. Kreusel; N. E. Bechrakis; H. P. Neumann; M. H. Foerster (2006) Pars plana vitrectomy for juxtapapillary capillary retinal angioma Am J Ophthalmol 141, 587-9.

M. Horndasch, S. Lienkamp, E. Springer, A. Schmitt, H. Pavenstadt, G. Walz and J. Gloy (2006) The C/EBP homologous protein CHOP (GADD153) is an inhibitor of Wnt/TCF signals Oncogene 25, 3397-407.

M. F. Bek, M. Bayer, B. Muller, S. Greiber, D. Lang, A. Schwab, C. August, E. Springer, R. Rohrbach, T. B. Huber, T. Benzing and H. Pavenstadt (2006) Expression and function of C/EBP homology protein (GADD153) in podocytes Am J Pathol 168, 20-32.

I. Brink; O. Schaefer; M. Walz; H. P. Neumann (2006) Fluorine-18 DOPA PET imaging of paraganglioma syndrome Clin Nucl Med 31, 39-41.

V. I. Vougioukas; S. Glasker; U. Hubbe; A. Berlis; H. Omran; H. P. Neumann; V. Van Velthoven (2006) Surgical treatment of hemangioblastomas of the central nervous system in pediatric patients Childs Nerv Syst 22, 1149-53.

D. Schmidt; H. P. Neumann (2005) Spontaneous regression of retinal angiomatous lesions in v. Hippel-Lindau disease (VHL) Eur J Med Res 10, 532-4.

B. Schermer, K. Hopker, H. Omran, C. Ghenoiu, M. Fliegauf, A. Fekete, J. Horvath, M. Kottgen, M. Hackl, S. Zschiedrich, T. B. Huber, A. Kramer-Zucker, H. Zentgraf, A. Blaukat, G. Walz and T. Benzing (2005) Phosphorylation by casein kinase 2 induces PACS-1 binding of nephrocystin and targeting to cilia EMBO J 24, 4415-24.

F. Schiavi; C. C. Boedeker; B. Bausch; M. Peczkowska; C. F. Gomez; T. Strassburg; C. Pawlu; M. Buchta; M. Salzmann; M. M. Hoffmann; A. Berlis; I. Brink; M. Cybulla; M. Muresan; M. A. Walter; F. Forrer; M. Valimaki; A. Kawecki; Z. Szutkowski; J. Schipper; M. K. Walz; P. Pigny; C. Bauters; J. E. Willet-Brozick; B. E. Baysal; A. Januszewicz; C. Eng; G. Opocher; H. P. Neumann (2005) Predictors and prevalence of paraganglioma syndrome associated with mutations of the SDHC gene JAMA 294, 2057-63.

C. Bergmann, F. Kupper, C. P. Schmitt, U. Vester, T. J. Neuhaus, J. Senderek and K. Zerres (2005) Multi-exon deletions of the PKHD1 gene cause autosomal recessive polycystic kidney disease (ARPKD) J Med Genet 42, e63.

A. G. Kramer-Zucker, S. Wiessner, A. M. Jensen and I. A. Drummond (2005) Organization of the pronephric filtration apparatus in zebrafish requires Nephrin, Podocin and the FERM domain protein Mosaic eyes Dev Biol 285, 316-29.

G. Walz (2005) Slit or pore? A mutation of the ion channel TRPC6 causes FSGS Nephrol Dial Transplant 20, 1777-9.

C. Pawlu; B. Bausch; N. Reisch; H. P. Neumann (2005) Genetic testing for pheochromocytoma-associated syndromes Ann Endocrinol (Paris) 66, 178-85.

J. A. Grunkemeyer, C. Kwoh, T. B. Huber and A. S. Shaw (2005) CD2-associated protein (CD2AP) expression in podocytes rescues lethality of CD2AP deficiency J Biol Chem 280, 29677-81.

M. Kottgen and G. Walz (2005) Subcellular localization and trafficking of polycystins Pflugers Arch 451, 286-93.

C. Pawlu; B. Bausch; H. P. Neumann (2005) Mutations of the SDHB and SDHD genes Fam Cancer 4, 49-54.

M. Cybulla; E. Schaefer; S. Wendt; H. Ling; S. M. Krober; U. Hovelborn; S. Schandelmaier; R. Rohrbach; H. P. Neumann (2005) Chronic renal failure and proteinuria in adulthood: Fabry disease predominantly affecting the kidneys Am J Kidney Dis 45, e82-9.

M. K. Walz; S. Petersenn; J. A. Koch; K. Mann; H. P. Neumann; K. W. Schmid (2005) Endoscopic treatment of large primary adrenal tumours Br J Surg 92, 719-23.

M. Simons, J. Gloy, A. Ganner, A. Bullerkotte, M. Bashkurov, C. Kronig, B. Schermer, T. Benzing, O. A. Cabello, A. Jenny, M. Mlodzik, B. Polok, W. Driever, T. Obara and G. Walz (2005) Inversin, the gene product mutated in nephronophthisis type II, functions as a molecular switch between Wnt signaling pathways Nat Genet 37, 537-43.

P. Gerke, L. Sellin, O. Kretz, D. Petraschka, H. Zentgraf, T. Benzing and G. Walz (2005) NEPH2 is located at the glomerular slit diaphragm, interacts with nephrin and is cleaved from podocytes by metalloproteinases J Am Soc Nephrol 16, 1693-702.

H. P. Neumann; M. Cybulla; H. Shibata; M. Oya; M. Naruse; E. Higashihara; T. Terachi; H. Ling; H. Takami; T. Shuin; M. Murai (2005) New genetic causes of pheochromocytoma: current concepts and the clinical relevance Keio J Med 54, 15-21.

T. Nambirajan; K. Leeb; H. P. Neumann; U. B. Graubner; G. Janetschek (2005) Laparoscopic adrenal surgery for recurrent tumours in patients with hereditary phaeochromocytoma Eur Urol 47, 622-6.

T. B. Huber and T. Benzing (2005) The slit diaphragm: a signaling platform to regulate podocyte function Curr Opin Nephrol Hypertens 14, 211-6.

P. S. Goerttler, C. Kreutz, J. Donauer, D. Faller, T. Maiwald, E. Marz, B. Rumberger, T. Sparna, A. Schmitt-Graff, J. Wilpert, J. Timmer, G. Walz and H. L. Pahl (2005) Gene expression profiling in polycythaemia vera: overexpression of transcription factor NF-E2 Br J Haematol 129, 138-50.

A. G. Kramer-Zucker, F. Olale, C. J. Haycraft, B. K. Yoder, A. F. Schier and I. A. Drummond (2005) Cilia-driven fluid flow in the zebrafish pronephros, brain and Kupffer's vesicle is required for normal organogenesis Development 132, 1907-21.

C. D. Margetts; D. Astuti; D. C. Gentle; W. N. Cooper; A. Cascon; D. Catchpoole; M. Robledo; H. P. Neumann; F. Latif; E. R. Maher (2005) Epigenetic analysis of HIC1, CASP8, FLIP, TSP1, DCR1, DCR2, DR4, DR5, KvDMR1, H19 and preferential 11p15.5 maternal-allele loss in von Hippel-Lindau and sporadic phaeochromocytomas Endocr Relat Cancer 12, 161-72.

E. Schafer; K. Baron; U. Widmer; P. Deegan; H. P. Neumann; G. Sunder-Plassmann; J. O. Johansson; C. Whybra; M. Ries; G. M. Pastores; A. Mehta; M. Beck; A. Gal (2005) Thirty-four novel mutations of the GLA gene in 121 patients with Fabry disease Hum Mutat 25, 412.

M. Joerger; D. Koeberle; H. P. Neumann; S. Gillessen (2005) Von Hippel-Lindau disease--a rare disease important to recognize Onkologie 28, 159-63.

C. C. Boedeker; H. P. Neumann; G. J. Ridder; W. Maier; J. Schipper (2005) Paragangliomas in patients with mutations of the SDHD gene Otolaryngol Head Neck Surg 132, 467-70.

C. Bergmann, J. Senderek, E. Windelen, F. Kupper, I. Middeldorf, F. Schneider, C. Dornia, S. Rudnik-Schoneborn, M. Konrad, C. P. Schmitt, T. Seeman, T. J. Neuhaus, U. Vester, J. Kirfel, R. Buttner and K. Zerres (2005) Clinical consequences of PKHD1 mutations in 164 patients with autosomal-recessive polycystic kidney disease (ARPKD) Kidney Int 67, 829-48.

M. Kottgen, T. Benzing, T. Simmen, R. Tauber, B. Buchholz, S. Feliciangeli, T. B. Huber, B. Schermer, A. Kramer-Zucker, K. Hopker, K. C. Simmen, C. C. Tschucke, R. Sandford, E. Kim, G. Thomas and G. Walz (2005) Trafficking of TRPP2 by PACS proteins represents a novel mechanism of ion channel regulation EMBO J 24, 705-16.

C. Bergmann, J. Senderek and E. Windelen (2005) Clinical consequences of PKHD1 mutations in 164 patients with autosomal recessive polycystic kidney disease (ARPKD) Kidney Int, 829-48.

C. Bergmann, F. Küpper and C. Dornia (2005) Algorithm for efficient PKHD1 mutation screening in autosomal recessive polycystic kidney disease (ARPKD) Hum Mutat, 225-31.

O. Beck; W. J. Fassbender; P. Beyer; S. Kriener; H. P. Neumann; T. Klingebiel; T. Lehrnbecher (2004) Pheochromocytoma in childhood: implication for further diagnostic procedures Acta Paediatr 93, 1630-4.

M. K. Walz; K. Peitgen; D. Diesing; S. Petersenn; O. E. Janssen; T. Philipp; K. A. Metz; K. Mann; K. W. Schmid; H. P. Neumann (2004) Partial versus total adrenalectomy by the posterior retroperitoneoscopic approach: early and long-term results of 325 consecutive procedures in primary adrenal neoplasias World J Surg 28, 1323-9.

D. Astuti; M. Morris; C. Krona; F. Abel; D. Gentle; T. Martinsson; P. Kogner; H. P. Neumann; R. Voutilainen; C. Eng; P. Rustin; F. Latif; E. R. Maher (2004) Investigation of the role of SDHB inactivation in sporadic phaeochromocytoma and neuroblastoma Br J Cancer 91, 1835-41.

H. Ling; M. Cybulla; O. Schaefer; C. Arnold; M. Schories; H. P. Neumann (2004) When to look for Von Hippel-Lindau disease in gastroenteropancreatic neuroendocrine tumors? Neuroendocrinology 80 Suppl 1, 39-46.

C. C. Boedeker; G. J. Ridder; H. P. Neumann; W. Maier; J. Schipper (2004) [Diagnosis and management of cervical paragangliomas: the Freiburg experience] Laryngorhinootologie 83, 585-92.

Z. Allibhai; G. Rodrigues; E. Brecevic; H. P. Neumann; E. Winquist (2004) Malignant pheochromocytoma associated with germline mutation of the SDHB gene J Urol 172, 1409-10.

G. Eisenhofer; S. R. Bornstein; F. M. Brouwers; N. K. Cheung; P. L. Dahia; R. R. de Krijger; T. J. Giordano; L. A. Greene; D. S. Goldstein; H. Lehnert; W. M. Manger; J. M. Maris; H. P. Neumann; K. Pacak; B. L. Shulkin; D. I. Smith; A. S. Tischler; W. F. Young, Jr. (2004) Malignant pheochromocytoma: current status and initiatives for future progress Endocr Relat Cancer 11, 423-36.

H. P. Neumann; C. Pawlu; M. Peczkowska; B. Bausch; S. R. McWhinney; M. Muresan; M. Buchta; G. Franke; J. Klisch; T. A. Bley; S. Hoegerle; C. C. Boedeker; G. Opocher; J. Schipper; A. Januszewicz; C. Eng (2004) Distinct clinical features of paraganglioma syndromes associated with SDHB and SDHD gene mutations JAMA 292, 943-51.

B. Buchholz, R. Tauber, D. Steffl, G. Walz and M. Kottgen (2004) An inwardly rectifying whole cell current induced by Gq-coupled receptors Biochem Biophys Res Commun 322, 177-85.

J. Schipper; C. C. Boedeker; W. Maier; H. P. Neumann (2004) [Paragangliomas of the head and neck. Part 2: Therapy and follow-up] HNO 52, 651-60; quiz 661.

J. Schipper; C. C. Boedeker; W. Maier; H. P. Neumann (2004) [Paragangliomas in the head-/neck region. I: Classification and diagnosis] HNO 52, 569-74; quiz 575.

C. Bergmann, J. Senderek, F. Schneider, C. Dornia, F. Kupper, T. Eggermann, S. Rudnik-Schoneborn, J. Kirfel, M. Moser, R. Buttner and K. Zerres (2004) PKHD1 mutations in families requesting prenatal diagnosis for autosomal recessive polycystic kidney disease (ARPKD) Hum Mutat 23, 487-95.

C. Bergmann, J. Senderek, F. Kupper, F. Schneider, C. Dornia, E. Windelen, T. Eggermann, S. Rudnik-Schoneborn, J. Kirfel, L. Furu, L. F. Onuchic, S. Rossetti, P. C. Harris, S. Somlo, L. Guay-Woodford, G. G. Germino, M. Moser, R. Buttner and K. Zerres (2004) PKHD1 mutations in autosomal recessive polycystic kidney disease (ARPKD) Hum Mutat 23, 453-63.

K. Rath; K. Taxis; G. Walz; C. H. Gleiter; S. M. Li; L. Heide (2004) Pharmacokinetic study of artemisinin after oral intake of a traditional preparation of Artemisia annua L. (annual wormwood) Am J Trop Med Hyg 70, 128-32.

F. Jochimsen, W. Gruening, T. Arnould, M. S. Segal, M. S. Kruskall, R. Colgrove, Jr. and G. Walz (2004) Thrombotic microangiopathy associated with unusual viral sequences in HIV-1-positive patients Nephrol Dial Transplant 19, 1129-35.

J. Hoefele; E. Otto; H. Felten; K. Kuhn; T. A. Bley; I. Zauner; F. Hildebrandt; H. P. Neumann (2004) Clinical and histological presentation of 3 siblings with mutations in the NPHP4 gene Am J Kidney Dis 43, 358-64.

S. Vanharanta; M. Buchta; S. R. McWhinney; S. K. Virta; M. Peczkowska; C. D. Morrison; R. Lehtonen; A. Januszewicz; H. Jarvinen; M. Juhola; J. P. Mecklin; E. Pukkala; R. Herva; M. Kiuru; N. N. Nupponen; L. A. Aaltonen; H. P. Neumann; C. Eng (2004) Early-onset renal cell carcinoma as a novel extraparaganglial component of SDHB-associated heritable paraganglioma Am J Hum Genet 74, 153-9.

O. Gimm; C. A. Koch; A. Januszewicz; G. Opocher; H. P. Neumann (2004) The genetic basis of pheochromocytoma Front Horm Res 31, 45-60.

M. Leverkus; H. P. Neumann; E. B. Brocker; H. Hamm; J. Mayer (2003) Soft nodules at the tip of the tongue of a 26-year-old man Arch Dermatol 139, 1647-52.

S. N. Piper; G. Haisch; B. Kumle; G. A. Walz; T. Breining; P. Mattinger; J. Boldt (2003) [Effects of esmolol- and sodium nitroprusside-induced controlled hypotension on hepatocellular integrity in patients undergoing endonasal sinus surgery] Anasthesiol Intensivmed Notfallmed Schmerzther 38, 781-6.

V. Van Velthoven; P. C. Reinacher; J. Klisch; H. P. Neumann; S. Glasker (2003) Treatment of intramedullary hemangioblastomas, with special attention to von Hippel-Lindau disease Neurosurgery 53, 1306-13; discussion 1313-4.

A. Berlis; M. Schumacher; J. Spreer; H. P. Neumann; V. van Velthoven (2003) Subarachnoid haemorrhage due to cervical spinal cord haemangioblastomas in a patient with von Hippel-Lindau disease Acta Neurochir (Wien) 145, 1009-13; discussion 1013.

T. Leung, I. Soll, S. J. Arnold, R. Kemler and W. Driever (2003) Direct binding of Lef1 to sites in the boz promoter may mediate pre-midblastula-transition activation of boz expression Dev Dyn 228, 424-32.

T. B. Huber, M. Simons, B. Hartleben, L. Sernetz, M. Schmidts, E. Gundlach, M. A. Saleem, G. Walz and T. Benzing (2003) Molecular basis of the functional podocin-nephrin complex: mutations in the NPHS2 gene disrupt nephrin targeting to lipid raft microdomains Hum Mol Genet 12, 3397-405.

G. Walz (2003) [Pathogenetic aspectics of nephrotic syndrome] Internist (Berl) 44, 1075-82.

P. F. Zipfel; H. P. Neumann; M. Jozsi (2003) Genetic screening in haemolytic uraemic syndrome Curr Opin Nephrol Hypertens 12, 653-7.

S. R. McWhinney; G. Boru; P. K. Binkley; M. Peczkowska; A. A. Januszewicz; H. P. Neumann; C. Eng (2003) Intronic single nucleotide polymorphisms in the RET protooncogene are associated with a subset of apparently sporadic pheochromocytoma and may modulate age of onset J Clin Endocrinol Metab 88, 4911-6.

M. T. Wolf; B. E. Mucha; M. Attanasio; I. Zalewski; S. M. Karle; H. P. Neumann; N. Rahman; B. Bader; C. A. Baldamus; E. Otto; R. Witzgall; A. Fuchshuber; F. Hildebrandt (2003) Mutations of the Uromodulin gene in MCKD type 2 patients cluster in exon 4, which encodes three EGF-like domains Kidney Int 64, 1580-7.

T. B. Huber and T. Benzing (2003) [Molecular genetics in nephrology. Genetic kidney diseases provide clues for understanding the pathogenesis of proteinuria] Ther Umsch 60, 435-7.

H. P. Neumann; M. Salzmann; B. Bohnert-Iwan; T. Mannuelian; C. Skerka; D. Lenk; B. U. Bender; M. Cybulla; P. Riegler; A. Konigsrainer; U. Neyer; A. Bock; U. Widmer; D. A. Male; G. Franke; P. F. Zipfel (2003) Haemolytic uraemic syndrome and mutations of the factor H gene: a registry-based study of German speaking countries J Med Genet 40, 676-81.

J. Donauer, B. Rumberger, M. Klein, D. Faller, J. Wilpert, T. Sparna, G. Schieren, R. Rohrbach, P. Dern, J. Timmer, P. Pisarski, G. Kirste and G. Walz (2003) Expression profiling on chronically rejected transplant kidneys Transplantation 76, 539-47.

L. Furu, L. F. Onuchic, A. Gharavi, X. Hou, E. L. Esquivel, Y. Nagasawa, C. Bergmann, J. Senderek, E. Avner, K. Zerres, G. G. Germino, L. M. Guay-Woodford and S. Somlo (2003) Milder presentation of recessive polycystic kidney disease requires presence of amino acid substitution mutations J Am Soc Nephrol 14, 2004-14.

E. A. Otto, B. Schermer, T. Obara, J. F. O'Toole, K. S. Hiller, A. M. Mueller, R. G. Ruf, J. Hoefele, F. Beekmann, D. Landau, J. W. Foreman, J. A. Goodship, T. Strachan, A. Kispert, M. T. Wolf, M. F. Gagnadoux, H. Nivet, C. Antignac, G. Walz, I. A. Drummond, T. Benzing and F. Hildebrandt (2003) Mutations in INVS encoding inversin cause nephronophthisis type 2, linking renal cystic disease to the function of primary cilia and left-right axis determination Nat Genet 34, 413-20.

H. Olbrich, M. Fliegauf, J. Hoefele, A. Kispert, E. Otto, A. Volz, M. T. Wolf, G. Sasmaz, U. Trauer, R. Reinhardt, R. Sudbrak, C. Antignac, N. Gretz, G. Walz, B. Schermer, T. Benzing, F. Hildebrandt and H. Omran (2003) Mutations in a novel gene, NPHP3, cause adolescent nephronophthisis, tapeto-retinal degeneration and hepatic fibrosis Nat Genet 34, 455-9.

S. M. Arnold; R. Strecker; K. Scheffler; J. Spreer; J. Schipper; H. P. Neumann; J. Klisch (2003) Dynamic contrast enhancement of paragangliomas of the head and neck: evaluation with time-resolved 2D MR projection angiography Eur Radiol 13, 1608-11.

K. Zerres, S. Rudnik-Schoneborn, J. Senderek, T. Eggermann and C. Bergmann (2003) Autosomal recessive polycystic kidney disease (ARPKD) J Nephrol 16, 453-8.

T. B. Huber, B. Hartleben, J. Kim, M. Schmidts, B. Schermer, A. Keil, L. Egger, R. L. Lecha, C. Borner, H. Pavenstadt, A. S. Shaw, G. Walz and T. Benzing (2003) Nephrin and CD2AP associate with phosphoinositide 3-OH kinase and stimulate AKT-dependent signaling Mol Cell Biol 23, 4917-28.

K. M. Kreusel; N. E. Bechrakis; H. P. Neumann; M. H. Foerster (2003) A sporadic case of von Hippel-Lindau disease with a secondary maculopathy as the presenting sign Acta Ophthalmol Scand 81, 309-10.

T. Manuelian; J. Hellwage; S. Meri; J. Caprioli; M. Noris; S. Heinen; M. Jozsi; H. P. Neumann; G. Remuzzi; P. F. Zipfel (2003) Mutations in factor H reduce binding affinity to C3b and heparin and surface attachment to endothelial cells in hemolytic uremic syndrome J Clin Invest 111, 1181-90.

P. Gerke, T. B. Huber, L. Sellin, T. Benzing and G. Walz (2003) Homodimerization and heterodimerization of the glomerular podocyte proteins nephrin and NEPH1 J Am Soc Nephrol 14, 918-26.

S. Hoegerle; N. Ghanem; C. Altehoefer; J. Schipper; I. Brink; E. Moser; H. P. Neumann (2003) 18F-DOPA positron emission tomography for the detection of glomus tumours Eur J Nucl Med Mol Imaging 30, 689-94.

E. Deuerling, H. Patzelt, S. Vorderwulbecke, T. Rauch, G. Kramer, E. Schaffitzel, A. Mogk, A. Schulze-Specking, H. Langen and B. Bukau (2003) Trigger Factor and DnaK possess overlapping substrate pools and binding specificities Mol Microbiol 47, 1317-28.

M. J. Bek, S. Wahle, B. Muller, T. Benzing, T. B. Huber, M. Kretzler, C. Cohen, A. Busse-Grawitz and H. Pavenstadt (2003) Stra13, a prostaglandin E2-induced gene, regulates the cellular redox state of podocytes FASEB J 17, 682-4.

T. B. Huber, M. Schmidts, P. Gerke, B. Schermer, A. Zahn, B. Hartleben, L. Sellin, G. Walz and T. Benzing (2003) The carboxyl terminus of Neph family members binds to the PDZ domain protein zonula occludens-1 J Biol Chem 278, 13417-21.

C. Bergmann, J. Senderek, B. Sedlacek, I. Pegiazoglou, P. Puglia, T. Eggermann, S. Rudnik-Schoneborn, L. Furu, L. F. Onuchic, M. De Baca, G. G. Germino, L. Guay-Woodford, S. Somlo, M. Moser, R. Buttner and K. Zerres (2003) Spectrum of mutations in the gene for autosomal recessive polycystic kidney disease (ARPKD/PKHD1) J Am Soc Nephrol 14, 76-89.

L. Sellin, T. B. Huber, P. Gerke, I. Quack, H. Pavenstadt and G. Walz (2003) NEPH1 defines a novel family of podocin interacting proteins FASEB J 17, 115-7.

G. Walz (2002) [Pathogenesis of cystic kidney diseases] Verh Dtsch Ges Pathol 86, 138-44.

K. G. Fischer, T. B. Huber, A. Henger, E. Fink, E. Schwertfeger, L. C. Rump and H. Pavenstadt (2002) Eluate derived by extracorporal antibody-based immunoadsorption elevates the cytosolic Ca2+ concentration in podocytes via B2 kinin receptors Kidney Blood Press Res 25, 384-93.

E. W. Kuehn, K. M. Park, S. Somlo and J. V. Bonventre (2002) Kidney injury molecule-1 expression in murine polycystic kidney disease American journal of physiology. Renal physiology 283, F1326-36

Y. Nagasawa, S. Matthiesen, L. F. Onuchic, X. Hou, C. Bergmann, E. Esquivel, J. Senderek, Z. Ren, R. Zeltner, L. Furu, E. Avner, M. Moser, S. Somlo, L. Guay-Woodford, R. Buttner, K. Zerres and G. G. Germino (2002) Identification and characterization of Pkhd1, the mouse orthologue of the human ARPKD gene J Am Soc Nephrol 13, 2246-58.

H. P. Neumann (2002) Imaging vs biochemical testing for pheochromocytoma JAMA 288, 314-5; author reply 315.

T. Benzing, M. Kottgen, M. Johnson, B. Schermer, H. Zentgraf, G. Walz and E. Kim (2002) Interaction of 14-3-3 protein with regulator of G protein signaling 7 is dynamically regulated by tumor necrosis factor-alpha J Biol Chem 277, 32954-62.

T. B. Huber, H. C. Reinhardt, M. Exner, J. A. Burger, D. Kerjaschki, M. A. Saleem and H. Pavenstadt (2002) Expression of functional CCR and CXCR chemokine receptors in podocytes J Immunol 168, 6244-52.

M. K. Walz; K. Peitgen; H. P. Neumann; O. E. Janssen; T. Philipp; K. Mann (2002) Endoscopic treatment of solitary, bilateral, multiple, and recurrent pheochromocytomas and paragangliomas World J Surg 26, 1005-12.

M. Peczkowska; J. Gessek; A. Januszewicz; H. P. Neumann; M. Januszewicz; H. Janaszek-Sitkowska; A. Prejbisz; M. Kabat; J. Skierski; W. Ciesla; M. Szostek (2002) Pheochromocytoma of the urinary bladder coexisting with another extra-adrenal tumour--case report of a 19-year-old male patient Blood Press 11, 101-5.

J. Reiser; G. von Gersdorff; M. Simons; K. Schwarz; C. Faul; L. Giardino; T. Heider; M. Loos; P. Mundel (2002) Novel concepts in understanding and management of glomerular proteinuria Nephrol Dial Transplant 17, 951-5.

H. P. Neumann; B. Bausch; S. R. McWhinney; B. U. Bender; O. Gimm; G. Franke; J. Schipper; J. Klisch; C. Altehoefer; K. Zerres; A. Januszewicz; C. Eng; W. M. Smith; R. Munk; T. Manz; S. Glaesker; T. W. Apel; M. Treier; M. Reineke; M. K. Walz; C. Hoang-Vu; M. Brauckhoff; A. Klein-Franke; P. Klose; H. Schmidt; M. Maier-Woelfle; M. Peczkowska; C. Szmigielski (2002) Germ-line mutations in nonsyndromic pheochromocytoma N Engl J Med 346, 1459-66.

P. Reichardt; T. W. Apel; M. Domula; R. B. Trobs; I. Krause; U. Bierbach; H. P. Neumann; W. Kiess (2002) Recurrent polytopic chromaffin paragangliomas in a 9-year-old boy resulting from a novel germline mutation in the von Hippel-Lindau gene J Pediatr Hematol Oncol 24, 145-8.

H. P. Neumann; S. Hoegerle; T. Manz; K. Brenner; O. Iliopoulos (2002) How many pathways to pheochromocytoma? Semin Nephrol 22, 89-99.

C. Nickel, T. Benzing, L. Sellin, P. Gerke, A. Karihaloo, Z. X. Liu, L. G. Cantley and G. Walz (2002) The polycystin-1 C-terminal fragment triggers branching morphogenesis and migration of tubular kidney epithelial cells J Clin Invest 109, 481-9.

W. O. Lui; J. Chen; S. Glasker; B. U. Bender; C. Madura; S. K. Khoo; E. Kort; C. Larsson; H. P. Neumann; B. T. Teh (2002) Selective loss of chromosome 11 in pheochromocytomas associated with the VHL syndrome Oncogene 21, 1117-22.

S. Hoegerle; E. Nitzsche; C. Altehoefer; N. Ghanem; T. Manz; I. Brink; M. Reincke; E. Moser; H. P. Neumann (2002) Pheochromocytomas: detection with 18F DOPA whole body PET--initial results Radiology 222, 507-12.

R. Greger, R. Schreiber, M. Mall, A. Wissner, A. Hopf, M. Briel, M. Bleich, R. Warth and K. Kunzelmann (2001) Cystic fibrosis and CFTR Pflugers Arch 443 Suppl 1, S3-7.

K. Schwarz; M. Simons; J. Reiser; M. A. Saleem; C. Faul; W. Kriz; A. S. Shaw; L. B. Holzman; P. Mundel (2001) Podocin, a raft-associated component of the glomerular slit diaphragm, interacts with CD2AP and nephrin J Clin Invest 108, 1621-9.

H. Patzelt, S. Rudiger, D. Brehmer, G. Kramer, S. Vorderwulbecke, E. Schaffitzel, A. Waitz, T. Hesterkamp, L. Dong, J. Schneider-Mergener, B. Bukau and E. Deuerling (2001) Binding specificity of Escherichia coli trigger factor Proc Natl Acad Sci U S A 98, 14244-9.

D. Astuti; A. Agathanggelou; S. Honorio; A. Dallol; T. Martinsson; P. Kogner; C. Cummins; H. P. Neumann; R. Voutilainen; P. Dahia; C. Eng; E. R. Maher; F. Latif (2001) RASSF1A promoter region CpG island hypermethylation in phaeochromocytomas and neuroblastoma tumours Oncogene 20, 7573-7.

H. P. Neumann; P. Riegler; W. Huber; R. Corradini; A. Sessa; D. Fontana; U. Wetterauer; G. Janetschek (2001) The challenge of kidney lesions in von Hippel-Lindau disease Contrib Nephrol, 193-207.

E. Schaffitzel, S. Rudiger, B. Bukau and E. Deuerling (2001) Functional dissection of trigger factor and DnaK: interactions with nascent polypeptides and thermally denatured proteins Biol Chem 382, 1235-43.

T. B. Huber, M. Kottgen, B. Schilling, G. Walz and T. Benzing (2001) Interaction with podocin facilitates nephrin signaling J Biol Chem 276, 41543-6.

M. Simons; K. Schwarz; W. Kriz; A. Miettinen; J. Reiser; P. Mundel; H. Holthofer (2001) Involvement of lipid rafts in nephrin phosphorylation and organization of the glomerular slit diaphragm Am J Pathol 159, 1069-77.

H. P. Neumann; M. Reincke; C. Eng (2001) Case 13-2001: genetic testing in pheochromocytoma N Engl J Med 345, 547-8.

T. Benzing, P. Gerke, K. Hopker, F. Hildebrandt, E. Kim and G. Walz (2001) Nephrocystin interacts with Pyk2, p130(Cas), and tensin and triggers phosphorylation of Pyk2 Proc Natl Acad Sci U S A 98, 9784-9.

B. U. Bender; C. Eng; M. Olschewski; D. P. Berger; J. Laubenberger; C. Altehofer; G. Kirste; M. Orszagh; V. van Velthoven; H. Miosczka; D. Schmidt; H. P. Neumann (2001) VHL c.505 T>C mutation confers a high age related penetrance but no increased overall mortality J Med Genet 38, 508-14.

S. Frenzel; T. W. Apel; P. H. Heidemann; K. Zerres; H. P. Neumann; H. G. Dorr (2001) Phaeochromocytoma associated with a de novo VHL mutation as form fruste of von Hippel-Lindau disease Eur J Pediatr 160, 421-4.

S. Glasker; B. U. Bender; T. W. Apel; V. van Velthoven; L. M. Mulligan; J. Zentner; H. P. Neumann (2001) Reconsideration of biallelic inactivation of the VHL tumour suppressor gene in hemangioblastomas of the central nervous system J Neurol Neurosurg Psychiatry 70, 644-8.

G. Janetschek; H. P. Neumann (2001) Laparoscopic surgery for pheochromocytoma Urol Clin North Am 28, 97-105.

R. K. Chatha; A. M. Johnson; P. G. Rothberg; R. R. Townsend; H. P. Neumann; P. A. Gabow (2001) Von Hippel-Lindau disease masquerading as autosomal dominant polycystic kidney disease Am J Kidney Dis 37, 852-8.

T. Manz; W. Grotz; M. Orszagh; B. Volk; G. Kirste; H. P. Neumann (2001) A patient with neurological deficits and seizures after renal transplantation Nephrol Dial Transplant 16, 631-3.

R. Schreiber, P. Kindle, T. Benzing, G. Walz and K. Kunzelmann (2001) Control of the cystic fibrosis transmembrane conductance regulator by alphaG(i) and RGS proteins Biochem Biophys Res Commun 281, 917-23.

D. H. Vandorpe, M. N. Chernova, L. Jiang, L. K. Sellin, S. Wilhelm, A. K. Stuart-Tilley, G. Walz and S. L. Alper (2001) The cytoplasmic C-terminal fragment of polycystin-1 regulates a Ca2+-permeable cation channel J Biol Chem 276, 4093-101.

O. Gimm; M. Armanios; H. Dziema; H. P. Neumann; C. Eng (2000) Somatic and occult germ-line mutations in SDHD, a mitochondrial complex II gene, in nonfamilial pheochromocytoma Cancer Res 60, 6822-5.

K. M. Kreusel; N. E. Bechrakis; T. Heinichen; L. Neumann; H. P. Neumann; M. H. Foerster (2000) Retinal angiomatosis and von Hippel-Lindau disease Graefes Arch Clin Exp Ophthalmol 238, 916-21.

B. U. Bender; M. Gutsche; S. Glasker; B. Muller; G. Kirste; C. Eng; H. P. Neumann (2000) Differential genetic alterations in von Hippel-Lindau syndrome-associated and sporadic pheochromocytomas J Clin Endocrinol Metab 85, 4568-74.

A. Januszewicz; H. P. Neumann; I. Lon; C. Szmigielski; B. Symonides; M. Kabat; T. W. Apel; B. Wocial; M. Lapinski; W. Januszewicz (2000) Incidence and clinical relevance of RET proto-oncogene germline mutations in pheochromocytoma patients J Hypertens 18, 1019-23.

L. M. Guay-Woodford, C. J. Wright, G. Walz and G. A. Churchill (2000) Quantitative trait loci modulate renal cystic disease severity in the mouse bpk model J Am Soc Nephrol 11, 1253-60.

T. Benzing, M. B. Yaffe, T. Arnould, L. Sellin, B. Schermer, B. Schilling, R. Schreiber, K. Kunzelmann, G. G. Leparc, E. Kim and G. Walz (2000) 14-3-3 interacts with regulator of G protein signaling proteins and modulates their activity J Biol Chem 275, 28167-72.

J. F. Roijers; T. Apel; H. P. Neumann; U. V. Arnim; C. J. Lips; J. W. Hoppener (2000) Internally shortened menin protein as a consequence of alternative RNA splicing due to a germline deletion in the multiple endocrine neoplasia type 1 gene Int J Mol Med 5, 611-4.

W. Kuehn (2000) Michelangelo's gouty knee Lancet 355, 1104.

D. Schmidt; E. Natt; H. P. Neumann (2000) Long-term results of laser treatment for retinal angiomatosis in von Hippel-Lindau disease Eur J Med Res 5, 47-58.

S. J. Arnold, J. Stappert, A. Bauer, A. Kispert, B. G. Herrmann and R. Kemler (2000) Brachyury is a target gene of the Wnt/beta-catenin signaling pathway Mech Dev 91, 249-58.

P. Riegler; W. Huber; R. Corradini; H. P. Neumann; S. Glaesker; A. Sessa (2000) Von Hippel-Lindau disease: the role of gene analysis in affected families Nephron 84, 95-7.

M. Simons; R. Saffrich; J. Reiser; P. Mundel (1999) Directed membrane transport is involved in process formation in cultured podocytes J Am Soc Nephrol 10, 1633-9.

T. Benzing, R. Brandes, L. Sellin, B. Schermer, S. Lecker, G. Walz and E. Kim (1999) Upregulation of RGS7 may contribute to tumor necrosis factor-induced changes in central nervous function Nat Med 5, 913-8.

E. Kim, T. Arnould, L. Sellin, T. Benzing, N. Comella, O. Kocher, L. Tsiokas, V. P. Sukhatme and G. Walz (1999) Interaction between RGS7 and polycystin Proc Natl Acad Sci U S A 96, 6371-6.

A. Hopf, R. Schreiber, M. Mall, R. Greger and K. Kunzelmann (1999) Cystic fibrosis transmembrane conductance regulator inhibits epithelial Na+ channels carrying Liddle's syndrome mutations J Biol Chem 274, 13894-9.

S. Ananth, B. Knebelmann, W. Gruning, M. Dhanabal, G. Walz, I. E. Stillman and V. P. Sukhatme (1999) Transforming growth factor beta1 is a target for the von Hippel-Lindau tumor suppressor and a critical growth factor for clear cell renal carcinoma Cancer Res 59, 2210-6.

R. Schreiber, A. Hopf, M. Mall, R. Greger and K. Kunzelmann (1999) The first-nucleotide binding domain of the cystic-fibrosis transmembrane conductance regulator is important for inhibition of the epithelial Na+ channel Proc Natl Acad Sci U S A 96, 5310-5.

T. Arnould, L. Sellin, T. Benzing, L. Tsiokas, H. T. Cohen, E. Kim and G. Walz (1999) Cellular activation triggered by the autosomal dominant polycystic kidney disease gene product PKD2 Mol Cell Biol 19, 3423-34.

W. Gruning, T. Arnould, F. Jochimsen, L. Sellin, S. Ananth, E. Kim and G. Walz (1999) Modulation of renal tubular cell function by RGS3 Am J Physiol 276, F535-43.

L. Tsiokas, T. Arnould, C. Zhu, E. Kim, G. Walz and V. P. Sukhatme (1999) Specific association of the gene product of PKD2 with the TRPC1 channel Proc Natl Acad Sci U S A 96, 3934-9.

E. W. Kuehn, H. J. Anders, J. R. Bogner, J. Obermaier, F.D. Goebel and D. Schlondorff (1999) Hypocalcaemia in HIV infection and AIDS Journal of internal medicine 245, 69-73

S. Orsulic, O. Huber, H. Aberle, S. Arnold and R. Kemler (1999) E-cadherin binding prevents beta-catenin nuclear localization and beta-catenin/LEF-1-mediated transactivation J Cell Sci 112 ( Pt 8), 1237-45.

E. Kim, T. Arnould, L. K. Sellin, T. Benzing, M. J. Fan, W. Gruning, S. Y. Sokol, I. Drummond and G. Walz (1999) The polycystic kidney disease 1 gene product modulates Wnt signaling J Biol Chem 274, 4947-53.

S. Waldegger, B. Fakler, M. Bleich, P. Barth, A. Hopf, U. Schulte, A. E. Busch, S. G. Aller, J. N. Forrest, Jr., R. Greger and F. Lang (1999) Molecular and functional characterization of s-KCNQ1 potassium channel from rectal gland of Squalus acanthias Pflugers Arch 437, 298-304.

M. J. Fan, W. Gruning, G. Walz and S. Y. Sokol (1998) Wnt signaling and transcriptional control of Siamois in Xenopus embryos Proc Natl Acad Sci U S A 95, 5626-31.

T. B. Huber, J. Gloy, A. Henger, P. Schollmeyer, R. Greger, P. Mundel and H. Pavenstadt (1998) Catecholamines modulate podocyte function J Am Soc Nephrol 9, 335-45.

T. Arnould, E. Kim, L. Tsiokas, F. Jochimsen, W. Gruning, J. D. Chang and G. Walz (1998) The polycystic kidney disease 1 gene product mediates protein kinase C alpha-dependent and c-Jun N-terminal kinase-dependent activation of the transcription factor AP-1 J Biol Chem 273, 6013-8.

L. Tsiokas, E. Kim, T. Arnould, V. P. Sukhatme and G. Walz (1997) Homo- and heterodimeric interactions between the gene products of PKD1 and PKD2 Proc Natl Acad Sci U S A 94, 6965-70.

H. Haller, U. Kunzendorf, K. Sacherer, C. Lindschau, G. Walz, A. Distler and F. C. Luft (1997) T cell adhesion to P-selectin induces tyrosine phosphorylation of pp125 focal adhesion kinase and other substrates J Immunol 158, 1061-7.

U. Kunzendorf, T. Pohl, S. Bulfone-Paus, H. Krause, M. Notter, A. Onu, G. Walz and T. Diamantstein (1996) Suppression of cell-mediated and humoral immune responses by an interleukin-2-immunoglobulin fusion protein in mice J Clin Invest 97, 1204-10.

C. Wanner, W. Bartens, G. Walz, M. Nauck and P. Schollmeyer (1995) Protein loss and genetic polymorphism of apolipoprotein(a) modulate serum lipoprotein(a) in CAPD patients Nephrol Dial Transplant 10, 75-81.

U. Kunzendorf, S. Kruger-Krasagakes, M. Notter, H. Hock, G. Walz and T. Diamantstein (1994) A sialyl-Le(x)-negative melanoma cell line binds to E-selectin but not to P-selectin Cancer Res 54, 1109-12.

U. Kunzendorf, M. Notter, H. Hock, A. Distler, T. Diamantstein and G. Walz (1993) T cells bind to the endothelial adhesion molecule GMP-140 (P-selectin) Transplantation 56, 1213-7.

C. Stevens, G. Walz, C. Singaram, M. L. Lipman, B. Zanker, A. Muggia, D. Antonioli, M. A. Peppercorn and T. B. Strom (1992) Tumor necrosis factor-alpha, interleukin-1 beta, and interleukin-6 expression in inflammatory bowel disease Dig Dis Sci 37, 818-26.

J. Markovic-Lipkovski, C. A. Muller, G. Engler-Blum, F. Strutz, W. Kuhn, T. Risler, W. Lauchart and G. A. Muller (1992) Human cytomegalovirus in rejected kidney grafts; detection by polymerase chain reaction Nephrol Dial Transplant 7, 865-70.

G. A. Muller, C. A. Muller, G. Engler-Blum, W. Kuhn, T. Risler, A. Bohle and J. Markovic-Lipkovski (1992) Human cytomegalovirus in immunoglobulin A nephropathy: detection by polymerase chain reaction Nephron 62, 389-93.

U. Kunzendorf, J. Brockmoller, U. Bickel, F. Jochimsen, G. Walz, I. Roots and G. Offermann (1991) Promotion of B cell stimulation in graft recipients through a mechanism distinct from interleukin-6 gene superinduction Transplantation 51, 1312-5.

U. Kunzendorf, G. Walz, J. Brockmoeller, H. H. Neumayer, F. Jochimsen, I. Roots, G. Offermann and T. B. Strom (1991) Effects of diltiazem upon metabolism and immunosuppressive action of cyclosporine in kidney graft recipients Transplantation 52, 280-4.

G. Walz, C. Stevens, B. Zanker, L. B. Melton, S. C. Clark, M. Suthanthiran and T. B. Strom (1991) The role of interleukin-6 in mitogenic T-cell activation: detection of interleukin-2 heteronuclear RNA by polymerase chain reaction Cell Immunol 134, 511-9.

A. Aruffo, W. Kolanus, G. Walz, P. Fredman and B. Seed (1991) CD62/P-selectin recognition of myeloid and tumor cell sulfatides Cell 67, 35-44.

P. K. Sehajpal, B. Li, B. Zanker, V. K. Murthi, A. Subramaniam, V. K. Sharma, D. Estin, E. Y. Skolnik, K. J. Wieder, G. Walz and et al. (1991) The molecular basis for the synergism between the CD3/alpha beta T cell receptor and the CD2 antigen-derived signals in promoting T-cell proliferation Transplantation 51, 468-74.

D. Camerini, G. Walz, W. A. Loenen, J. Borst and B. Seed (1991) The T cell activation antigen CD27 is a member of the nerve growth factor/tumor necrosis factor receptor gene family J Immunol 147, 3165-9.

G. Walz, B. Zanker, C. Barth, K. J. Wieder, S. C. Clark and T. B. Strom (1990) Transcriptional modulation of human IL-6 gene expression by verapamil J Immunol 144, 4242-8.

F. Keller, U. Kunzendorf, G. Walz, A. Schwarz and G. Offermann (1990) Slow accumulation of cyclosporin metabolites as measured by specific and nonspecific cyclosporin RIA Int J Clin Pharmacol Ther Toxicol 28, 167-75.

G. Walz, B. Zanker, J. R. Murphy and T. B. Strom (1990) A kinetic analysis of the effects of interleukin-2 diphtheria toxin fusion protein upon activated T cells Transplantation 49, 198-201.

B. Zanker, G. Walz, K. J. Wieder and T. B. Strom (1990) Evidence that glucocorticosteroids block expression of the human interleukin-6 gene by accessory cells Transplantation 49, 183-5.

G. Walz, U. Kunzendorf, O. Josimovic-Alasevic, L. Preuschoff, A. Schwarz, F. Keller, G. Asmus, G. Offermann, T. Diamantstein and A. Distler (1990) Soluble interleukin 2 receptor and tissue polypeptide antigen serum concentrations in end-stage renal failure Nephron 56, 157-61.

G. Walz, B. Zanker, L. B. Melton, M. Suthanthiran and T. B. Strom (1990) Possible association of the immunosuppressive and B cell lymphoma-promoting properties of cyclosporine Transplantation 49, 191-4.

K. J. Wieder, G. Walz, B. Zanker, P. Sehajpal, V. K. Sharma, E. Skolnik, T. B. Strom and M. Suthanthiran (1990) Physiologic signaling in normal human T-cells: mRNA phenotyping by northern blot analysis and reverse transcription-polymerase chain reaction Cell Immunol 128, 41-51.

G. Walz, A. Aruffo, W. Kolanus, M. Bevilacqua and B. Seed (1990) Recognition by ELAM-1 of the sialyl-Lex determinant on myeloid and tumor cells Science 250, 1132-5.

B. Zanker, G. Walz, K. J. Wieder, M. Moscovitch-Lopatin, B. R. Smith and T. B. Strom (1989) Verapamil selectively inhibits expression of interleukin-2 messenger RNA in mitogen activated mononuclear blood cells Transplant Proc 21, 85-7.

F. Keller, U. Kunzendorf, G. Walz, H. Haller and G. Offermann (1989) Saturable first-pass kinetics of propranolol J Clin Pharmacol 29, 240-5.

U. Kunzendorf, F. Keller, G. Walz, H. Haller, G. Offermann, K. Borner and H. Lode (1989) Multivariate analysis of aminoglycoside levels in hemodialysis patients Chemotherapy 35, 1-6.

U. Kunzendorf, J. Brockmoller, F. Jochimsen, F. Keller, I. Roots, G. Walz and G. Offermann (1989) Cyclosporin drug monitoring: comparison of four immunoassays and HPLC Klin Wochenschr 67, 438-41.

G. Walz, B. Zanker, K. Wieder, E. Hadro, M. Moscovitch-Lopatin, B. R. Smith and T. B. Strom (1989) Similar effects of cyclosporine and verapamil on lymphokine, interleukin 2 receptor, and proto-oncogene expression Transplantation 47, 331-4.

G. Walz, B. Zanker, K. Brand, C. Waters, F. Genbauffe, J. B. Zeldis, J. R. Murphy and T. B. Strom (1989) Sequential effects of interleukin 2-diphtheria toxin fusion protein on T-cell activation Proc Natl Acad Sci U S A 86, 9485-8.

G. Walz, U. Kunzendorf, H. Haller, F. Keller, G. Offermann, O. Josimovic-Alasevic and T. Diamantstein (1989) Factors influencing the response to hepatitis B vaccination of hemodialysis patients Nephron 51, 474-7.

G. Walz, U. Kunzendorf, A. Schwarz, R. Bauer, F. Keller and G. Offermann (1988) Elevated tissue polypeptide antigen as a risk factor for carpal tunnel syndrome in haemodialyzed patients Nephron 50, 83-4.

A. Schwarz and G. Walz (1988) [Beta 2 microglobulin. 2: Dialysis-associated amyloidosis] Fortschr Med 106, 334-7.

G. Walz and A. Schwarz (1988) [Beta 2 microglobulin. 1: Physiologic significance, behavior in kidney diseases and chronic hemodialysis] Fortschr Med 106, 331-3.

U. Kunzendorf, J. Brockmoller, F. Jochimsen, F. Keller, G. Walz and G. Offermann (1988) Cyclosporin metabolites and central-nervous-system toxicity Lancet 1, 1223.

G. Walz, U. Kunzendorf, F. Keller, R. Fitzner and G. Offermann (1988) Elevated tumor markers in hemodialysis patients Am J Nephrol 8, 187-9.

U. Kunzendorf, G. Walz, H. H. Neumayer, K. Wagner, F. Keller and G. Offermann (1987) [Effect of diltiazem on blood cyclosporin levels] Klin Wochenschr 65, 1101-3.

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